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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for ALK+ Non-Small-Cell Lung Carcinoma

A Real World Study of Ensartinib in Advanced ALK-positive NSCLC NCT05498064n/a1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Ensartinib A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer NCT06868277Phase 3304 sites๐Ÿ“ La Mesa๐Ÿ“ Los Alamitos๐Ÿ“ Newark AstraZeneca ยท Tests: Rilvegostomig, Pembrolizumab A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC NCT06627647Phase 3301 sites๐Ÿ“ Mobile๐Ÿ“ Chandler๐Ÿ“ Phoenix AstraZeneca ยท Tests: Rilvegostomig, Pembrolizumab, Carboplatin, Cisplatin, Pemetrexed Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC NCT05950139Phase 1, Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Peptide vaccine A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib NCT06378892Phase 29 sites๐Ÿ“ Aviano๐Ÿ“ Florence๐Ÿ“ Lido di Camaiore Centro di Riferimento Oncologico - Aviano ยท Tests: Lorlatinib Efficacy of Platinum-based Chemotherapy Plus Immune Checkpoint Inhibitors for EGFR/ALK/ROS1 Mutant Lung Cancer NCT05284539Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Pemetrexed, Cisplatin, Bevacizumab Plus Pembrolizumab Savolitinib Plus Docetaxel as 2L in EGFR/ALK/ROS1/MET ex14m-wildtype NSCLC With MET Overexpression NCT05777278Phase 1, Phase 21 site๐Ÿ“ Guangzhou The First Affiliated Hospital of Guangzhou Medical Universiโ€ฆ ยท Tests: Savolitinib, Docetaxel ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma NCT05014464Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Crizotinib ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC NCT06426511Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab+Chemotherapy, Toripalimab+Chemotherapy followed by consolidation toripalimab Post Marketing Surveillance(PMS) Study of Lorviqua in Korea NCT05599412n/a1 site๐Ÿ“ Seoul Pfizer ยท Tests: Lorviqua Gilteritinib for the Treatment of ALK NSCLC NCT06225427Phase 13 sites๐Ÿ“ Los Angeles๐Ÿ“ Washington D.C.๐Ÿ“ Ann Arbor University of Michigan Rogel Cancer Center ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Echocardiography, Gilteritinib Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels NCT05525338Phase 48 sites๐Ÿ“ Villejuif๐Ÿ“ Nijmegen๐Ÿ“ Maastricht University Medical Center Groningen ยท Tests: Alectinib QL1706 Combined With Chemotherapy in the Treatment of Immune-mediated NSCLC NCT07330596Phase 21 site๐Ÿ“ Hefei Anhui Provincial Cancer Hospital ยท Tests: QL1706 combined with Chemotherapy, Chemotherapy A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements NCT03093116Phase 1, Phase 2165 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ La Jolla Turning Point Therapeutics, Inc. ยท Tests: Oral repotrectinib (TPX-0005) Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels NCT07360743Phase 24 sites๐Ÿ“ Bordeaux๐Ÿ“ Boulogne-Billancourt๐Ÿ“ Nice UNICANCER ยท Tests: Pembrolizumab, Cemiplimab Neoadjuvant WX-0593 in Resectable ALK-positive or ROS1-positive Non-small Cell Lung Cancer NCT05765877Phase 21 site๐Ÿ“ Jinan Pingping Song ยท Tests: WX-0593 Tablets Analysis of the Effectiveness and Safety of Lorlatinib in Untreated ALK-Positive NSCLC Patients in a French Real-World Context NCT06487078NA32 sites๐Ÿ“ Toulouse๐Ÿ“ Paris๐Ÿ“ Aix-en-Provence Pfizer ยท Tests: Lorlatinib A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma NCT05456256Phase 216 sites๐Ÿ“ Beverly Hills๐Ÿ“ Fountain Valley๐Ÿ“ Los Alamitos Lantern Pharma Inc. ยท Tests: LP-300, Pemetrexed, Carboplatin Lorlatinib as the First-line Treatment in China Advanced ALK+ NSCLC NCT06092086Phase 21 site๐Ÿ“ Guangzhou Guangdong Association of Clinical Trials ยท Tests: Loratinib Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer NCT05142189Phase 145 sites๐Ÿ“ Lexington๐Ÿ“ Louisville๐Ÿ“ Baltimore BioNTech SE ยท Tests: BNT116, Cemiplimab, Docetaxel, Carboplatin, Paclitaxel A Study on Exploring the Abscopal Effect Induced by Different Radioimmunotherapy Combination Patterns in the Treatment of Non-Small Cell Lung Cancer With Multiple Metastases NCT06947694Phase 21 site๐Ÿ“ Chongqing Xinqiao Hospital of Chongqing ยท Tests: chemotherapy + PD-1 inhibitors, chemotherapy + PD-1 inhibitors, chemotherapy + PD-1 inhibitors, chemotherapy + PD-1 inhโ€ฆ Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC NCT06765109Phase 3159 sites๐Ÿ“ Glendale๐Ÿ“ Newport Beach๐Ÿ“ Orange Nuvalent Inc. ยท Tests: Neladalkib (NVL-655), Alectinib Efficacy and Safety of Ivonescimab Monotherapy as First-Line Treatment for PD-L1-Positive, Driver Gene-Negative, Locally Advanced or Metastatic NSCLC: A Multicenter, Prospective, Real-World Cohort Study NCT07696832n/a1 site๐Ÿ“ Guangzhou Guangdong Association of Clinical Trials ยท Tests: Ivonescimab Injection Alectinib Followed by Concomitant Consolidation Radiation Therapy in Advanced NSCLC With ALK-rearrangement (A-SAB) NCT05724004NA1 site๐Ÿ“ Stockholm Karolinska University Hospital ยท Tests: SBRT/SRS/radiation therapy Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy NCT03042221n/a1 site๐Ÿ“ Aurora University of Colorado, Denver Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT NCT05236946Phase 31 site๐Ÿ“ Mumbai Tata Memorial Hospital ยท Tests: Stereotactic radiosurgery/whole brain radiotherapy, Tyrosine kinase inhibitor Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation NCT04322890Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Osimertinib, Alectinib 150 MG, Crizotinib 250 MG, Savolitinib, Crizotinib., Chemotherapy Study on the Optimal Combination Pattern of the Combined Treatment of Radiotherapy and Immunotherapy for the Abscopal Effect in Non-Small Cell Lung Cancer (NSCLC) With Multiple Metastases NCT06953843Phase 21 site๐Ÿ“ Chongqing Xinqiao Hospital of Chongqing ยท Tests: Benmelstobart combined with chemotherapy, Benmelstobart combined with chemotherapy, Benmelstobart combined with chemothโ€ฆ Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer NCT05241028Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Ensartinib
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