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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Leukemia of Ambiguous Lineage

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy NCT03959085Phase 3231 sites📍 Birmingham📍 Mobile📍 Anchorage Children's Oncology Group · Tests: Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration, Bone Marrow Biopsy, Bone Scan Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04047641Phase 1, Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Cladribine, Cytarabine, Idarubicin, Quizartinib Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites📍 San Francisco📍 Aurora📍 Atlanta Andrew E. Place, MD · Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies NCT03802695Phase 112 sites📍 Duarte📍 Sacramento📍 Stanford Orca Biosystems, Inc. · Tests: OrcaGraft (Orca-Q) Personalized NK Cell Therapy in CBT NCT02727803Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan, Clofarabine, Cyclophosphamide Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms NCT04797767Phase 1, Phase 21 site📍 Seattle University of Washington · Tests: Cladribine, Cytarabine, Mitoxantrone, Recombinant Granulocyte Colony-Stimulating Factor, Venetoclax Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant Feasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic Stem Cell Transplantation NCT07256210Phase 21 site📍 Moscow Federal Research Institute of Pediatric Hematology, Oncolog… · Tests: Donor-derived Natural Killer Cell Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL NCT04872478Phase 13 sites📍 Atlanta📍 Atlanta📍 New York Meryx, Inc. · Tests: MRX-2843 Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer NCT07046078Phase 21 site📍 Seattle Fred Hutchinson Cancer Center · Tests: Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy,… Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation NCT03683433Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Azacitidine, Enasidenib Mesylate Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) NCT06533579Phase 1, Phase 211 sites📍 Duarte📍 Los Angeles📍 Denver Vironexis Biotherapeutics Inc. · Tests: Dose Level 1, VNX-101, Dose Level 2, VNX-101, Dose Level 3, VNX-101, Dose Level 4, VNX-101 Subcutaneous Blinatumomab for Treatment of Adult Patients With CD19-Positive Mixed Phenotype Acute Leukemia (MPAL) NCT07222579Phase 21 site📍 Morgantown West Virginia University · Tests: Subcutaneous Blinatumomab Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage NCT04440267Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: vincristine, daunorubicin, cyclophosphamide, L-Asparaginase, prednisone The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study NCT04726241Phase 1, Phase 2184 sites📍 Birmingham📍 Mobile📍 Anchorage PedAL BCU, LLC · Tests: Biospecimen Collection Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) NCT06390319Phase 24 sites📍 San Diego📍 Charlotte📍 Tulsa St. Jude Children's Research Hospital · Tests: Dexamethasone, Vincristine, Daunorubicin, Calaspargase pegol, Dasatinib Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia NCT06177067Phase 110 sites📍 San Diego📍 Aurora📍 Atlanta St. Jude Children's Research Hospital · Tests: Revumenib, Venetoclax, Azacitidine, intrathecal (IT) chemotherapy, Cytarabine Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant NCT06575296Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Echocardiography, Electronic Health Record Review Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) NCT05322850Phase 1, Phase 24 sites📍 Gainesville📍 Miami📍 Miami University of Florida · Tests: Orca-Q Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT NCT06551584Phase 11 site📍 Palo Alto Stanford University · Tests: ORCA-T Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis NCT06756152Phase 2, Phase 31 site📍 Moscow Federal Research Institute of Pediatric Hematology, Oncolog… · Tests: Conditioning regimen: Treosulfan 42 g/m2/course or total body irradiation 12 Gray/course, Etoposide 60 mg/kg , Fludarab… 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome NCT03670966Phase 1, Phase 21 site📍 Seattle Fred Hutchinson Cancer Center · Tests: Astatine At 211 Anti-CD45 Monoclonal Antibody BC8-B10, Cyclophosphamide, Total-Body Irradiation, Peripheral Blood Stem … Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies NCT05476770Phase 131 sites📍 Los Angeles📍 Orange📍 San Francisco Therapeutic Advances in Childhood Leukemia Consortium · Tests: Tagraxofusp, Fludarabine, Cytarabine, Dexamethasone, Vincristine Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial NCT06355583Phase 28 sites📍 Birmingham📍 Leeds📍 London Imperial College London · Tests: EBX-102, Placebo MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing NCT05794880NA1 site📍 Milwaukee Medical College of Wisconsin · Tests: Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi) Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome NCT07216443Phase 26 sites📍 Los Angeles📍 Tampa📍 Hackensack Orca Biosystems, Inc. · Tests: Orca-T HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site📍 Seattle Fred Hutchinson Cancer Center · Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site📍 Seattle Fred Hutchinson Cancer Center · Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine Vitamin A and D Supplementation in Allogeneic HCT NCT06508099Phase 21 site📍 Saint Petersburg St. Petersburg State Pavlov Medical University · Tests: Vitamin A, Vitamin D3 BeFluBu vs FluBuRux Conditioning in Haploidentical HCT NCT06477549Phase 21 site📍 Saint Petersburg St. Petersburg State Pavlov Medical University · Tests: Bendamustine Hydrochloride, Ruxolitinib
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