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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung Mechanics NCT07188038NA2 sites📍 Gothenburg📍 Gothenburg Vastra Gotaland Region · Tests: Low positive end-expiratory pressure, Medium positive end-expiratory pressure, High positive end-expiratory pressure Effects of Low Tidal Volume and Airway Pressure Release Ventilation on Lung Tissue Mechanics in ARDS Patients Under Mechanical Ventilation: A Prospective Randomized Crossover Study NCT06790875NA1 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: Airway Pressure Release Ventilation (APRV) VExUS in Ards Patients and Association with AKI NCT06805409n/a1 site📍 Créteil Assistance Publique - Hôpitaux de Paris BALance: ARDS Deconvolution by Bronchoalveolar Lavage Multiomics and Radiomics NCT07633366n/a1 site📍 Vienna Medical University of Vienna · Tests: sampling blood, Lavage with physiologic saline solution CytOSorb TreatMent Of Critically Ill PatientS Registry NCT05146336n/a28 sites📍 Klagenfurt📍 Vienna📍 Aachen CytoSorbents, Inc · Tests: CytoSorb Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma NCT03368092Phase 31 site📍 Strasbourg University Hospital, Strasbourg, France · Tests: Dornase Alfa Inhalant Solution [Pulmozyme], Placebos EXTEND ARDS-J Esophageal Pressure Study NCT06734988n/a1 site📍 Sapporo Sapporo Medical University JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart NCT06701669Phase 241 sites📍 Birmingham📍 Fresno📍 Long Beach PPD Development, LP · Tests: Cohort B: paridiprubart, Cohort B: placebo Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS NCT07449572Phase 12 sites📍 Richmond📍 Richmond HTIC, Inc · Tests: HT31-1, Saline (0.9%, sterile, for infusion) Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI NCT07248995NA1 site📍 Thessaloniki Theodoros Schizodimos · Tests: Stepwise Positive End-Expiratory Pressure (PEEP) Increase Protocol Prone Position Assessed by 3D EIT NCT07083973n/a1 site📍 Beijing Peking Union Medical College Hospital · Tests: Prone position Physiologic Effects of Continuous Positive Airway Pressure and High Flow Nasal Oxygenation in Patients with Acute Respiratory Distress Syndrome. NCT06694311NA1 site📍 Barcelona Ricard Mellado Artigas · Tests: CPAP, HFNO 50 L/min Lung EIT Image Guide Ventilation in ARDS NCT07309783NA1 site📍 Beijing Peking Union Medical College Hospital · Tests: Recruitment maneuver and PEEP setting guided by EIT, PEEP setting according to routine practice, Prone positioning guid… A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+ NCT07326215NA10 sites📍 Beijing📍 Guangzhou📍 Shenzhen Vantive Health LLC · Tests: PrismaLung+, Invasive Mechanical Ventilation A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome NCT07558538EARLY Phase 11 site📍 Shanghai Shanghai Zhongshan Hospital · Tests: Recombinant Human Keratinocyte Growth Factor-2 for Inhalation (Lyophilized Powder) The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial NCT06203405NA1 site📍 Bangkok Siriraj Hospital · Tests: Titrating sedation targeting both optimal P0.1 and appropriate arousal level, Fentanyl, Midazolam, Propofol, Dexmedetom… Pleural Strain by Speckle-Tracking Ultrasound: Feasibility and Driving Pressure Associations NCT06911450n/a1 site📍 Wuhu First Affiliated Hospital of Wannan Medical College Electrical Impedance Tomography-Based Prognostic Model for ARDS NCT06967207n/a4 sites📍 Guangzhou📍 Wuhan📍 Wuhan XiaoJing Zou,MD · Tests: Not applicable- observational study JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab NCT06701682Phase 241 sites📍 Birmingham📍 Fresno📍 Long Beach PPD Development, LP · Tests: Cohort A: vilobelimab, Cohort A: placebo A Real World Study of Respiratory Critical Disease. NCT07165717n/a1 site📍 Shanghai Ming Zhong · Tests: No Intervention: Observational Cohort Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS NCT06696638NA1 site📍 Wuhan XiaoJing Zou,MD · Tests: EIT-guided Phigh settings during APRV ALI/ARDS Clinical Sub-phenotyping Study NCT06123962n/a1 site📍 Beijing China-Japan Friendship Hospital · Tests: Collect peripheral blood and bronchoalveolar lavage fluid EIT-Guided Ventilator Settings in AHRF NCT06936618NA1 site📍 Bangkok Mahidol University · Tests: Electrical Impedance Tomography (EIT), Enlight 2100 Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) NCT06001645n/a4 sites📍 Cagliari📍 Milan📍 Pisa Università Vita-Salute San Raffaele · Tests: Blood and bronchoalveolar fluid collection and analysis, Chest CT scan Free for Weaning ECMO vs Respiratory Driven Study NCT06876415NA4 sites📍 Lyon📍 Marseille📍 Nice Assistance Publique Hopitaux De Marseille · Tests: P0.1 and delta Poeso integration into the decanulation decision Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial NCT05002478NA1 site📍 Vienna Medical University of Vienna · Tests: Prone positioning Digital Early Warning System for Acute Lung Injury in Liver Surgery NCT07070362n/a4 sites📍 Beijing📍 Beijing📍 Chongqing Beijing Tsinghua Chang Gung Hospital Lung Injury is One of the Primary Causes of Morbidity and Mortality in Critically Ill Patients. These Patients Will be Monitored for: 1) Immune Cell Activation 2) Blood-based Biomarkers. In Vitro Models Derived From These Samples Will be Treated With Novel Agent PIP-2 to Evaluate Its Efficacy. NCT07125079n/a1 site📍 Philadelphia University of Pennsylvania Observational, Non-interventional Biomarker and Endotyping Study NCT07675265n/a1 site📍 Urbana Prenosis, Inc. Complications of the Alveolar Opening Maneuver in Children on Mechanical Ventilation NCT07233304n/a1 site📍 Canuelas Hospital de Alta Complejidad en Red · Tests: Alveolar Opening Maneuver and PEEP Titration (AOM+P)
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