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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Adenocarcinoma of the Rectum

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer NCT05672524Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Trastuzumab, Tucatinib Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps NCT05080673NA493 sites📍 Fairbanks📍 Goodyear📍 Kingman NRG Oncology · Tests: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 NCT07595874Phase 211 sites📍 Goodyear📍 Corona📍 Duarte City of Hope Medical Center · Tests: Balstilimab, Biospecimen Collection, Botensilimab, Computed Tomography, Magnetic Resonance Imaging Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits NCT03303547NA1 site📍 London Imperial College London · Tests: MRI mapping to guide pathological sampling of extranodal tumour deposits Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518Phase 1, Phase 23 sites📍 Beijing📍 Beijing📍 Shanghai GV20 Therapeutics · Tests: GV20-0251 Beyond TME Origins NCT02292641NA4 sites📍 Oslo📍 Harrow📍 Oxford Imperial College London · Tests: New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pe… Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy NCT06569368Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Metronidazole A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430Phase 1, Phase 213 sites📍 Los Angeles📍 Denver📍 New Haven GV20 Therapeutics · Tests: GV20-0251, GV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDA®], GV20-0251 and Pembrolizumab [KEYTRUDA®] The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors NCT04624555n/a1 site📍 Cleveland Case Comprehensive Cancer Center The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma NCT06266832Phase 21 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Adebrelimab, Oxaliplatin, Capecitabine, Short-course Radiation, Biopsy Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) NCT05663775Phase 21 site📍 Edmonton AHS Cancer Control Alberta · Tests: Mesalamine PET-imaging of Two Vartumabs in Patients With Solid Tumors NCT06645808EARLY Phase 11 site📍 Groningen Var2 Pharmaceuticals · Tests: 89Zr-DFO-N-Suc-F8scFv, 89Zr-DFO-N-Suc-C9scFv, PET/CT scan Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems NCT03961776n/a2 sites📍 Los Angeles📍 Marseille Institut Paoli-Calmettes · Tests: MRI-guided radiotherapy by on-board DWI sequences Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer NCT02107105n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Quality-of-Life Assessment, Questionnaire Administration A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial) NCT07669220Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Short-course Radiotherapy, SCRT, Toripalimab ADAR1 Expression Level in Rectal Cancer NCT07108348n/a1 site📍 Konya Necmettin Erbakan University · Tests: Adenosine deaminase acting on RNA1 SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC NCT07198165Phase 21 site📍 Shanghai Ruijin Hospital · Tests: PD-1 inhibitor based immunotherapy mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC NCT06791512Phase 31 site📍 Guangzhou Jun Huang · Tests: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody, mFOLFOX6 Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA) NCT06991465Phase 21 site📍 Montreal Neil Kopek · Tests: Radiation Therapy, FOLFOX regimen, Capecitabine Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer NCT04703101Phase 11 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Capecitabine, Fluorouracil, Intensity-Modulated Radiation Therapy, Leucovorin, Oxaliplatin A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum NCT07811193Phase 2122 sites📍 Tucson📍 Ann Arbor📍 Detroit Vividion Therapeutics, Inc. · Tests: VVD-133214, Pembrolizumab Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement NCT07104604Phase 22 sites📍 Shantou📍 Shantou Affiliated Cancer Hospital of Shantou University Medical Co… · Tests: Liposomal Irinotecan+Tislelizumab+Capecitabine+Rradiotherapy Dose Escalated Radiotherapy for Rectal Cancers Using MR-guided Radiotherapy NCT06854679NA1 site📍 Sutton Royal Marsden NHS Foundation Trust · Tests: Radiotherapy dose escalation Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates NCT07292298Phase 23 sites📍 Aurora📍 Rochester📍 Portland University of Colorado, Denver · Tests: High Rare Dose Rectal Brachytherapy Boost Asian Watch-and-Wait Database (AWWD) NCT06631443n/a1 site📍 Mumbai Tata Memorial Centre Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer NCT06197425Phase 31 site📍 Dijon Centre Hospitalier Universitaire Dijon · Tests: "FOLFIRI" cures, Trifluridine cures, BIOLOGICAL ASSESSMENT, Questionnaires, Thoracic-abdomino-pelvic scan or … Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer NCT07200141Phase 21 site📍 Beijing Peking Union Medical College Hospital · Tests: GTV 58.75 Gy/25 fractions(Simultaneous Integrated Boost), GTV 50 Gy/25 fractions(Simultaneous Integrated Boost), Concur… Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer. NCT07407465Phase 228 sites📍 Lyon📍 Marseille📍 Paris Gruppo Oncologico del Nord-Ovest · Tests: Trastuzumab-Deruxtecan (T-DXd), Capecitabine, Bevacizumab A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer NCT06637462NA6 sites📍 Middletown📍 Montvale📍 Commack Memorial Sloan Kettering Cancer Center · Tests: Endoscopy RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer NCT07735624Phase 23 sites📍 Boston📍 Boston📍 Boston Dana-Farber Cancer Institute · Tests: Botensilimab, Balstilimab
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