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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Adult Glioblastoma

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Castro Valley GT Medical Technologies, Inc. ยท Tests: GammaTile Key Longitudinal Associations With Risk and Glioblastoma Outcomes NCT06625684n/a1 site๐Ÿ“ Durham Duke University A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastinยฎ Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients NCT06496971Phase 32 sites๐Ÿ“ Taipei๐Ÿ“ Taoyuan NaviFUS Corporation ยท Tests: Bevacizumab, Microbubble, Low-Intensity Focused Ultrasound Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma NCT04547777Phase 11 site๐Ÿ“ Durham Darell Bigner ยท Tests: D2C7-IT, 2141-V11 A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma NCT07464925Phase 13 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ New York Tetragon Biosciences Ltd ยท Tests: GLIX1 Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites๐Ÿ“ Irvine๐Ÿ“ Los Angeles๐Ÿ“ Orange NRG Oncology ยท Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma NCT05083754Phase 11 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Retifanlimab, Temozolomide, Radiation Therapy Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells NCT06186401Phase 11 site๐Ÿ“ San Francisco Hideho Okada, MD, PhD ยท Tests: E-SYNC T Cells, Cyclophosphamide (non-investigational), Fludarabine (non-investigational), Leukapheresis, Surgical reseโ€ฆ The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) NCT06118723n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Jasper Gerritsen ยท Tests: Supramaximal resection, Maximal safe resection Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma NCT07145112Phase 11 site๐Ÿ“ Sacramento University of California, Davis ยท Tests: Laser interstitial thermal therapy, Lomustine Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma NCT07100730Phase 39 sites๐Ÿ“ Gold Coast๐Ÿ“ Melbourne๐Ÿ“ Perth Telix Pharmaceuticals (Innovations) Pty Limited ยท Tests: TLX-101-Tx + Lomustine, TLX101-Tx Hypofractionated Radiotherapy NCT06740955NA1 site๐Ÿ“ Changchun The First Hospital of Jilin University ยท Tests: hypofractionated postoperative radiotherapy, Conventionally fractionated postoperative radiotherapy Simultaneous Integrated Boost FDOPA Positron Emission Tomography (PET) Guided in Patients With Partially- or Non-operated Glioblastoma NCT05653622Phase 23 sites๐Ÿ“ Nancy๐Ÿ“ Strasbourg๐Ÿ“ Vandล“uvre-lรจs-Nancy Centre Paul Strauss ยท Tests: Integrated boost technique (SIB) guided by PET FDOPA Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Chicago Nationwide Children's Hospital ยท Tests: Ribociclib, Everolimus, Temozolomide (TMZ) A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations NCT04094610Phase 1, Phase 268 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Aurora Turning Point Therapeutics, Inc. ยท Tests: Oral repotrectinib (TPX-0005) The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) NCT06283927n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Jasper Gerritsen ยท Tests: Re-resection, Temozolomide, Lomustine, Re-irradiation, Experimental therapy Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature NCT06894225Phase 21 site๐Ÿ“ Singapore National Neuroscience Institute ยท Tests: ACT001 D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients NCT05734560Phase 1, Phase 21 site๐Ÿ“ Durham Darell Bigner ยท Tests: D2C7-IT, 2141-V11 Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis NCT06047379Phase 1, Phase 28 sites๐Ÿ“ Beverly Hills๐Ÿ“ Glendale๐Ÿ“ Los Angeles Neonc Technologies, Inc. ยท Tests: NEO212 Oral Capsule, Ipilimumab, Pembrolizumab, Nivolumab, Regorafenib Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures NCT07413796NA1 site๐Ÿ“ Warsaw Medical University of Warsaw ยท Tests: Absorbable running intradermal suture, Non-absorbable interrupted transdermal suture The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) NCT06146738n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Jasper Gerritsen ยท Tests: Palliative Care, Tumor biopsy, Tumor resection hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) NCT05052957Phase 21 site๐Ÿ“ Cleveland Leland Metheny ยท Tests: P140K-MGMT, O6-benzylguanine, Photon Based Radiotherapy, temozolomide, Filgrastim A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Gainesville University of Florida ยท Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liโ€ฆ Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors NCT07411690n/a1 site๐Ÿ“ Warsaw Medical University of Warsaw Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma NCT05954858NA1 site๐Ÿ“ New York Northwell Health ยท Tests: Tissue autograft of pedicled temporoparietal fascial (TPF) or pericranial flap to bypass the blood brain barrier (BBB) Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site๐Ÿ“ Toronto Sunnybrook Health Sciences Centre ยท Tests: Focused Ultrasound Next Generation Dome Helmet, Definityยฎ Vial for (Perflutren Lipid Microsphere) Injectable Suspension Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites๐Ÿ“ Miami๐Ÿ“ New York Baptist Health South Florida ยท Tests: Ruxolitinib, Temozolomide, Radiation Therapy Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study NCT06954636n/a2 sites๐Ÿ“ Essen๐Ÿ“ Mรผnster Sied Kebir ยท Tests: olfactory testing (threshold and identification test) Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors NCT07523529Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Autologous dual-target CAR-T cells selected from the predefined target library., Fludarabine, Cyclophosphamide Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma NCT07551336Phase 11 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Dual-target CAR-NK cells, Cyclophosphamide, Intracranial catheter/reservoir for locoregional delivery, Fludarabine
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