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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Cholangiocarcinoma

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Tampa Elevar Therapeutics ยท Tests: Lirafugratinib A Study of LY4337713 in Participants With FAP-Positive Solid Tumors NCT07213791Phase 130 sites๐Ÿ“ Newport Beach๐Ÿ“ Stanford๐Ÿ“ Miami Eli Lilly and Company ยท Tests: LY4337713 A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Chongqing Precision Biotech Co., Ltd ยท Tests: CEA-targeted CAR-T cells Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma NCT05874414Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Orlando Genfit ยท Tests: GNS561 + Trametinib A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4ฮฑ srRNA in Treating Advanced ICC Patients NCT06583993EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: HNF4ฮฑ srRNA A Study of MGC028 in Participants With Advanced Solid Tumors NCT06723236Phase 17 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Boston MacroGenics ยท Tests: MGC028 Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion NCT06439485Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Pemigatinib, Atezolizumab, Bevacizumab Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract Cancer NCT07025174Phase 21 site๐Ÿ“ Hangzhou First Affiliated Hospital of Zhejiang University ยท Tests: PD-1/CTLA-4 Dual Functional Antibody, Gemcitabine, Cisplatin, Anlotinib, Oxaliplatin + 5-Fluorouracil/Leucovorin Clinical Study of VG161 in Advanced Intrahepatic Cholangiocarcinoma NCT06746480Phase 21 site๐Ÿ“ Hangzhou CNBG-Virogin Biotech (Shanghai) Ltd. ยท Tests: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell)) BOLD-100 in Combination With FOLFOX With or Without Bevacizumab for the Treatment of Advanced, Solid Tumours NCT04421820Phase 1, Phase 228 sites๐Ÿ“ Santa Monica๐Ÿ“ Tampa๐Ÿ“ Edmonton Bold Therapeutics, Inc. ยท Tests: BOLD-100 ยฑ FOLFOX ยฑ Bevacizumab Chemotherapy (Arm VII), BOLD-100 in combination with FOLFOX Chemotherapy (Arms I-VI) Lenvatinib, Tislelizumab Combined with Gemcitabine and Cisplatin (GPLET) in the Treatment of Advanced Cholangiocarcinoma NCT05823311Phase 31 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Lenvatinib, tislelizumab, gemcitabine and cisplatin, Gemcitabine and cisplatin Cryoablation Combined with Anti-PD-1 Antibody in Patients with Advanced Intrahepatic Cholangiocarcinoma NCT04299581Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Camrelizumab, US/CT-guided Percutaneous Cryoablation A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9 NCT07186842Phase 1, Phase 218 sites๐Ÿ“ Denver๐Ÿ“ Orlando๐Ÿ“ Detroit BioNTech SE ยท Tests: BNT329, CA19-9-targeting monoclonal antibody Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer NCT07641036Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-HC01 dual-target CARNK cells, Fludarabine, Cyclophosphamide Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study NCT05342194Phase 31 site๐Ÿ“ Shanghai Shanghai Junshi Bioscience Co., Ltd. ยท Tests: Toripalimab, Lenvatinib mesylate capsules, Placebo IV, Oral placebo, Oxaliplatin for injection Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial) NCT06859684Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: Durvalumab, hepatic arterial infusion chemotherapy (HAIC), Lenvatinib A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation NCT07458347Phase 19 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ Tampa Kestrel Therapeutics, Inc. ยท Tests: KST-6051, Gemcitabine/nab-paclitaxel, Cetuximab, Pembrolizumab, mFOLFOX6 HAIC Combined With Camrelizumab Plus Rivoceranib for Advanced Mixed Hepatocellular-cholangiocarcinoma (HCC-CCA) NCT07105748Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Camrelizumab, Rivoceranib (Apatinib), HAIC HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma NCT06858735Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Durvalumab, Gemcitabine, Cisplatin Perioperative Retlirafusp Alfa(Anti-PD-L1/TGF-ฮฒ Bifunctional Fusion Protein) Plus Famitinib and GEMOX-Based Hepatic Arterial Infusion Chemotherapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Multicenter, Single-Arm, Exploratory Phase II Trial NCT07847710Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Retlirafusp alfa, Famitinib malate, Gemcitabine & oxaliplatin, Capecitabine, S-1 Personalized Tumor Neoantigen mRNA Therapy for Advanced Intrahepatic Cholangiocarcinoma NCT06956716Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: individualized anti-tumor new antigen iNeo-Vac-R01 injection, Gemcitabine + cisplatin (GP), Sintilimab injection Lenvatinib, Tislelizumab Plus Gemcitabine and Cisplatin (GPLET) in Patients with Advanced Cholangiocarcinoma NCT05532059Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Lenvatinib, tislelizumab, gemcitabine and cisplatin, gemcitabine and cisplatin Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Cholangiocarcinoma NCT07070700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: QL1706 (bispecific antibody targeting PD-1 and CLTA-4), Lenvatinib, cryoablation HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma NCT04353375Phase 2, Phase 31 site๐Ÿ“ Beijing Hutchmed ยท Tests: HMPL-453 A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors NCT05150691Phase 1, Phase 2102 sites๐Ÿ“ Cerritos๐Ÿ“ Los Angeles๐Ÿ“ San Diego DualityBio Inc. ยท Tests: DB-1303/BNT323, Pertuzumab Injection, Ritonavir, Itraconazole A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement NCT05727176Phase 265 sites๐Ÿ“ La Jolla๐Ÿ“ Tampa๐Ÿ“ Detroit Taiho Oncology, Inc. ยท Tests: TAS-120 Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949Phase 21 site๐Ÿ“ Boston Beth Israel Deaconess Medical Center ยท Tests: Gemcitabine, Cisplatin, Durvalumab, Yttrium-90 A Study of GV20-0251 in Advanced or Refractory Solid Tumors NCT07106827Phase 11 site๐Ÿ“ Chengdu West China Hospital ยท Tests: GV20-0251 A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN) NCT06028724n/a1 site๐Ÿ“ Aviano Centro di Riferimento Oncologico - Aviano
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