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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Esophageal Adenocarcinoma

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) A Study of MT-4561 in Patients With Various Advanced Solid Tumors NCT06943521Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Columbus Tanabe Pharma America, Inc. ยท Tests: MT-4561 AB122 Platform Study NCT04999761Phase 19 sites๐Ÿ“ Aichi๐Ÿ“ Chiba๐Ÿ“ Ehime Taiho Pharmaceutical Co., Ltd. ยท Tests: AB122, AB122, TAS-116, TAS-120, TAS-115 A Study of LY4337713 in Participants With FAP-Positive Solid Tumors NCT07213791Phase 130 sites๐Ÿ“ Newport Beach๐Ÿ“ Stanford๐Ÿ“ Miami Eli Lilly and Company ยท Tests: LY4337713 Adebrelimab Combined With Nab-paclitaxel, Oxaliplatin and Tegafur (AOS) for Perioperative Treatment of Locally Advanced Resectable GC/GEJ NCT06808971Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Adebrelimab, Nab-paclitaxel, Oxaliplatin, Tegafur Gimeracil Oteracil Potassium Capsule Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies NCT03539822Phase 1, Phase 22 sites๐Ÿ“ Westwood๐Ÿ“ Pittsburgh Anwaar Saeed ยท Tests: Cabozantinib, Durvalumab, Tremelimumab TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer NCT06532799Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamid, Fludarabine, Interleukin-2, Pembrolizumab Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors NCT04900818Phase 121 sites๐Ÿ“ Orange๐Ÿ“ Aurora๐Ÿ“ Layfayette I-Mab Biopharma US Limited ยท Tests: TJ033721 (givastomig), TJ033721 (givastomig) , nivolumab, chemotherapy, TJ033721 (givastomig), chemotherapy, TJ033721 (โ€ฆ mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma NCT05677490Phase 3798 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage Alliance for Clinical Trials in Oncology ยท Tests: Fluorouracil, Leucovorin Calcium, Oxaliplatin, Irinotecan, Nivolumab Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus) NCT05177133Phase 28 sites๐Ÿ“ Amsterdam๐Ÿ“ Amsterdam๐Ÿ“ Eindhoven Academisch Medisch Centrum - Universiteit van Amsterdam (AMโ€ฆ ยท Tests: Capecitabine, Oxaliplatin, Retifanlimab A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma NCT07818018Phase 1, Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Intratumoral 2141-V11, Nivolumab, Fluoropyrimidine DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors. NCT07903415Phase 12 sites๐Ÿ“ Grand Rapids๐Ÿ“ San Antonio Pfizer ยท Tests: PF-08098488 Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors NCT06005493Phase 1, Phase 225 sites๐Ÿ“ Jacksonville๐Ÿ“ Rochester๐Ÿ“ New York AstraZeneca ยท Tests: AZD5863, AZD2936 Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma NCT07222657Phase 21 site๐Ÿ“ Weston Case Comprehensive Cancer Center ยท Tests: Standard of care chemotherapy, LNSC Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma NCT05651594Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Fluorouracil, Leucovorin Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06) NCT06469944Phase 1, Phase 250 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Louisville Merck Sharp & Dohme LLC ยท Tests: Pembrolizumab, Sacituzumab Tirumotecan (sac-TMT), Capecitabine, Leucovorin, Levoleucovorin A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success MacroGenics ยท Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion, Pembrollizumab, vobramitamab tavatecan A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Esophageal Varices Prophylaxis in Hepatocellular Carcinoma Treated With Atezolizumab and Bevacizumab NCT06961526NA1 site๐Ÿ“ Tanta Tanta University ยท Tests: Esophageal band ligation Will a Pre-therapy Exercise Intervention Improve the Outcomes of Patients With Advanced Oesophageal Cancer? NCT07375420NA1 site๐Ÿ“ Guildford University of Surrey ยท Tests: Low intensity exercise, High intensity exercise A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers NCT06422403Phase 21 site๐Ÿ“ Singapore National University Hospital, Singapore ยท Tests: Extended Dosing Interval - A, Extended Dosing Interval - B, Extended Dosing Interval - C, Standard of Care - A, Standarโ€ฆ Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors NCT03740256Phase 11 site๐Ÿ“ Houston Baylor College of Medicine ยท Tests: CAdVEC A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers NCT07544589Phase 17 sites๐Ÿ“ Duarte๐Ÿ“ Newport Beach๐Ÿ“ Tampa Dispatch Biotherapeutics ยท Tests: DISP-10 SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors NCT07812805Phase 15 sites๐Ÿ“ Glen Burnie๐Ÿ“ Pittsburgh๐Ÿ“ Seoul SK Life Science, Inc. ยท Tests: SKL35501, SKL35502 A Study of Sigvotatug Vedotin in Advanced Solid Tumors NCT04389632Phase 1158 sites๐Ÿ“ Anchorage๐Ÿ“ Fayetteville๐Ÿ“ Rogers Seagen, a wholly owned subsidiary of Pfizer ยท Tests: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatin Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma NCT06846346Phase 24 sites๐Ÿ“ Lyon๐Ÿ“ Marseille๐Ÿ“ Reims UNICANCER ยท Tests: Ivonescimab, FOLFOX regimen, Irinotecan, Paclitaxel
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