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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer NCT06196697Phase 21 site๐Ÿ“ Harbin Harbin Medical University ยท Tests: Cadonilimab, Ivonescimab, XELOX, SOX SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer NCT07464756Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: SHR-1701, apatinib, S-1 & Oxaliplatin Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors NCT06947291Phase 21 site๐Ÿ“ Hangzhou CSPC ZhongQi Pharmaceutical Technology Co., Ltd. ยท Tests: Glumetinib Tablets, Docetaxel for Injection (Albumin-bound) A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT07043400Phase 395 sites๐Ÿ“ Chandler๐Ÿ“ Los Alamitos๐Ÿ“ Colorado Springs BeOne Medicines ยท Tests: Subcutaneous Tislelizumab, Intravenous Tislelizumab, Cisplatin, Leucovorin, 5-fluorouracil (5-FU) First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dongying Qilu Hospital of Shandong University ยท Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin Neoadjuvant Iparomlimab and Tuvonralimab With Nab-P-SOX in Locally Advanced Gastric or Gastroesophageal Junction Cancer NCT07867392Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Iparomlimab and Tuvonralimab (QL1706), nab-P-SOX๏ผˆnab-paclitaxel, oxaliplatin, S-1๏ผ‰ A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma NCT07069712Phase 270 sites๐Ÿ“ Newark๐Ÿ“ Washington D.C.๐Ÿ“ Fairway AstraZeneca ยท Tests: Sonesitatug Vedotin, Rilvegostomig, Trastuzumab Deruxtecan (T-DXd), Capecitabine, 5-Fluorouracil (5-FU) A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC) NCT07289997Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Iparomlimab and Tuvonralimab Injection (QL1706) Adebrelimab Plus Apatinib Combined With SOX Regimen as Conversion Therapy for Gastric Cancer NCT07353684Phase 21 site๐Ÿ“ Beijing Beijing Friendship Hospital ยท Tests: Adebrelimab, Apatinib, SOX Chemotherapy SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT06649292Phase 31 site๐Ÿ“ Guangzhou Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A1904, Paclitaxel, Docetaxel, Irinotecan Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05) NCT05872685Phase 25 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou๐Ÿ“ Lishui Yu jiren ยท Tests: S1, Oxaliplatin, Serplulimab, Placebo Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer NCT07026149Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Apatinib+Camrelizumab+SOX, Preoperative Radiotherapy Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors NCT04900818Phase 121 sites๐Ÿ“ Orange๐Ÿ“ Aurora๐Ÿ“ Layfayette I-Mab Biopharma US Limited ยท Tests: TJ033721 (givastomig), TJ033721 (givastomig) , nivolumab, chemotherapy, TJ033721 (givastomig), chemotherapy, TJ033721 (โ€ฆ mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma NCT05677490Phase 3798 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage Alliance for Clinical Trials in Oncology ยท Tests: Fluorouracil, Leucovorin Calcium, Oxaliplatin, Irinotecan, Nivolumab Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma NCT07569068Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Tislelizumab, LM-302 and S-1, Tislelizumab combined with oxaliplatin and S-1 A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma. NCT07315750Phase 31 site๐Ÿ“ Beijing RemeGen Co., Ltd. ยท Tests: Disitamab Vedotin, Tislelizumab, CAPOX (oxaliplatin/capecitabine), Trastuzumab, Pembrolizumab A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen NCT06123494Phase 31 site๐Ÿ“ Shanghai Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR-A1811, Ramucirumab / Paclitaxel/ Docetaxel/ Irinotecan A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma NCT07818018Phase 1, Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Intratumoral 2141-V11, Nivolumab, Fluoropyrimidine DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Chemoradiotherapy and SHR-1701 in Patients With Unresectable Gastric Cancer NCT07689851Phase 23 sites๐Ÿ“ Shenzhen๐Ÿ“ Taiyuan๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: COPOX, Radiotherapy, SHR-1701 A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma NCT06341335Phase 31 site๐Ÿ“ Beijing Akeso ยท Tests: cadonilimab, pulocimab, paclitaxel, placebo A Study on the Safety and Efficacy of the Combination of Candenizumab, Lenvatinib, and SOX Regimen in the Treatment of HER2 Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Patients NCT06277024NA1 site๐Ÿ“ Fuzhou Fujian Medical University ยท Tests: Combination of Cardonizumab with Lenvatinib and SOX regimen Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors NCT06005493Phase 1, Phase 225 sites๐Ÿ“ Jacksonville๐Ÿ“ Rochester๐Ÿ“ New York AstraZeneca ยท Tests: AZD5863, AZD2936 Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma NCT05729646Phase 28 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou๐Ÿ“ Huzhou Yu jiren ยท Tests: Toripalimab, Oxaliplatin, S1 IBI343 in Combination With Sintilimab and SOX Regimen for Perioperative Treatment of Resectable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma NCT07483567Phase 21 site๐Ÿ“ Beijing Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI343,sintilimab,oxaliplatin,S-1, sintilimab,oxaliplatin,S-1 QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ NCT07716449Phase 31 site๐Ÿ“ Beijing Qilu Pharmaceutical Co., Ltd. ยท Tests: QLS31905, Sintilimab, Oxaliplatin, Capecitabine A Study of AK109 and AK104 in Advanced Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma NCT04982276Phase 1, Phase 21 site๐Ÿ“ Beijing Akeso ยท Tests: AK109, paclitaxel, paclitaxel, AK104
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