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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Malignant Neoplasm

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors NCT06821048Phase 11 site๐Ÿ“ Hangzhou Weijia Fang, MD ยท Tests: Intraperitoneal infusion of FAST CEA-targeted CAR-T Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel NCT06483555Phase 1, Phase 21 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: Gemcitabine, Nab paclitaxel, Erlotinib, NALIRIFOX, Folfirinox An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou๐Ÿ“ Hangzhou Beijing Tide Pharmaceutical Co., Ltd ยท Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma NCT05595408n/a1 site๐Ÿ“ Shanghai RenJi Hospital ยท Tests: Adjuvant chemotherapy, adjuvant immunotherapy A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors NCT04686682Phase 1, Phase 21 site๐Ÿ“ Tianjin Jacobio Pharmaceuticals Co., Ltd. ยท Tests: JAB-8263, JAB-8263 NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC NCT06405490Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Nanoliposomal Irinotecan+Oxaliplatin +Capecitabine+Cadonilimab Plasmodium Immunotherapy for Advanced Malignant Solid Tumors NCT04165590Phase 1, Phase 21 site๐Ÿ“ Kunming CAS Lamvac Biotech Co., Ltd. ยท Tests: Plasmodium immunotherapy A Pilot Randomized Controlled Trial of a Social Network Intervention NCT07393529NA1 site๐Ÿ“ Rochester University of Rochester ยท Tests: SONATA Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance NCT07483983Phase 27 sites๐Ÿ“ Villejuif๐Ÿ“ Bordeaux๐Ÿ“ Dijon Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: ASP3082 Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology NCT05756569Phase 24 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Biospecimen Collection, Computed Tomography, Enfortumab Vedotin, Magnetic Resonance Imaging, Pembrolizumab SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization NCT06389097n/a1 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Radium-223, 177Lu-DOTATATE, 177Lu-PSMA-617 T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer NCT02133196Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Aldesleukin, Fludarabine, Cyclophosphamide, Young TIL Care Coach-led Integrated Palliative Surgical Oncology and Rehabilitation Care Model for Advanced Cancer Patients NCT07133269NA2 sites๐Ÿ“ Singapore๐Ÿ“ Singapore Singapore General Hospital ยท Tests: Care Coach-led Palliative Surgical Oncology (PSO), Rehabilitation A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors NCT07250386Phase 11 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: CEA-targeted CAR-T (Intravenous), CEA-targeted CAR-T (Intrapleural) A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. NCT04116541Phase 213 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Caen Centre Leon Berard ยท Tests: HDM201, Ribociclib, Cabozantinib, Alectinib, Regorafenib Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: MRI and advanced MRI sequences AB122 Platform Study NCT04999761Phase 19 sites๐Ÿ“ Aichi๐Ÿ“ Chiba๐Ÿ“ Ehime Taiho Pharmaceutical Co., Ltd. ยท Tests: AB122, AB122, TAS-116, TAS-120, TAS-115 Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors NCT07174661NA1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Tucson QuantumLeap Healthcare Collaborative ยท Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Trasโ€ฆ Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors NCT06974110Phase 115 sites๐Ÿ“ Phoenix๐Ÿ“ San Diego๐Ÿ“ Tampa MOMA Therapeutics ยท Tests: MOMA-341, Irinotecan, Immunotherapy A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site๐Ÿ“ San Francisco Rahul Aggarwal ยท Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ Clinical Trial of TQB2922 for Injection in Patients With Advanced Cancers NCT06188624Phase 117 sites๐Ÿ“ Chongqing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharโ€ฆ ยท Tests: TQB2922 for injection Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) NCT06757634Phase 3239 sites๐Ÿ“ Jonesboro๐Ÿ“ Little Rock๐Ÿ“ Duarte Celcuity Inc ยท Tests: Arm A: Gedatolisib + Palbociclib + Fulvestrant, Arm B: Ribociclib + Fulvestrant, Arm C: Gedatolisib + Palbociclib + Letโ€ฆ Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT) NCT07312292Phase 21 site๐Ÿ“ Utrecht Niek Wijnen ยท Tests: Angiotensin II (Giaprezaยฎ), Yttrium-90 radioembolization Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION) NCT05475171Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Lorigerlimab A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour NCT06383871Phase 11 site๐Ÿ“ Tianjin Shandong Suncadia Medicine Co., Ltd. ยท Tests: HRS-7058 capsule/ HRS-7058 tablet A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors NCT06764771Phase 18 sites๐Ÿ“ Hackensack๐Ÿ“ Allentown๐Ÿ“ Germantown Bristol-Myers Squibb ยท Tests: BMS-986488, Adagrasib, Cetuximab, Nivolumab
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