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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Malignant Solid Neoplasm

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors NCT07408258Phase 13 sites๐Ÿ“ New York๐Ÿ“ Philadelphia๐Ÿ“ Houston OncoC4, Inc. ยท Tests: ONC-783 Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors NCT06821048Phase 11 site๐Ÿ“ Hangzhou Weijia Fang, MD ยท Tests: Intraperitoneal infusion of FAST CEA-targeted CAR-T An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou๐Ÿ“ Hangzhou Beijing Tide Pharmaceutical Co., Ltd ยท Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies NCT06484816Phase 11 site๐Ÿ“ Hangzhou Shenzhen TargetRx Co., Ltd. ยท Tests: TGRX-1942 A Study of AK109 Combined With AK104 in Patients With Advanced Solid Tumors NCT05142423Phase 1, Phase 21 site๐Ÿ“ Hangzhou Akeso ยท Tests: AK109+AK104 An Exploratory Study of Individualized Neo-antigen mRNA Cancer Vaccine InnoPCV in Advanced Solid Tumor Treatment NCT06497010EARLY Phase 11 site๐Ÿ“ Guiyang The Affiliated Hospital Of Guizhou Medical University ยท Tests: Biological: PD-1, Biological: InnoPCV Plasmodium Immunotherapy for Advanced Malignant Solid Tumors NCT04165590Phase 1, Phase 21 site๐Ÿ“ Kunming CAS Lamvac Biotech Co., Ltd. ยท Tests: Plasmodium immunotherapy A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours NCT06682780Phase 1, Phase 21 site๐Ÿ“ Shanghai LaNova Medicines Limited ยท Tests: LM-2417, Docetaxel, Toripalimab/Tirelizumab, Carboplatin, Niraparib A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors NCT07250386Phase 11 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: CEA-targeted CAR-T (Intravenous), CEA-targeted CAR-T (Intrapleural) A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. NCT04116541Phase 213 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Caen Centre Leon Berard ยท Tests: HDM201, Ribociclib, Cabozantinib, Alectinib, Regorafenib Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: MRI and advanced MRI sequences A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors NCT05932862Phase 116 sites๐Ÿ“ Fountain Valley๐Ÿ“ Jacksonville๐Ÿ“ Orlando Exelixis ยท Tests: XL309, Olaparib Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors NCT07174661NA1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors NCT06974110Phase 115 sites๐Ÿ“ Phoenix๐Ÿ“ San Diego๐Ÿ“ Tampa MOMA Therapeutics ยท Tests: MOMA-341, Irinotecan, Immunotherapy Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment NCT07036133Phase 14 sites๐Ÿ“ Cerritos๐Ÿ“ Chicago๐Ÿ“ Detroit Acrotech Biopharma Inc. ยท Tests: Pralatrexate Injection A Clinical Study of SYS6023 in Patients With Advanced Solid Tumors NCT07110883Phase 12 sites๐Ÿ“ Harbin๐Ÿ“ Shanghai CSPC Megalith Biopharmaceutical Co.,Ltd. ยท Tests: SYS6023 Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies NCT07098299Phase 110 sites๐Ÿ“ Bay City๐Ÿ“ Clarkston๐Ÿ“ Detroit Barbara Ann Karmanos Cancer Institute ยท Tests: Metformin A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site๐Ÿ“ San Francisco Rahul Aggarwal ยท Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection XTX301 in Patients With Advanced Solid Tumors NCT05684965Phase 1, Phase 212 sites๐Ÿ“ Sacramento๐Ÿ“ New Haven๐Ÿ“ Saint Louis Park Xilio Development, Inc. ยท Tests: XTX301 A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour NCT06383871Phase 11 site๐Ÿ“ Tianjin Shandong Suncadia Medicine Co., Ltd. ยท Tests: HRS-7058 capsule/ HRS-7058 tablet A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors NCT06764771Phase 18 sites๐Ÿ“ Hackensack๐Ÿ“ Allentown๐Ÿ“ Germantown Bristol-Myers Squibb ยท Tests: BMS-986488, Adagrasib, Cetuximab, Nivolumab TR64 in Patients With Advanced Solid Tumors NCT05649345Phase 12 sites๐Ÿ“ Bengbu๐Ÿ“ Shenyang Tarapeutics Science Inc. ยท Tests: TR64 Single Microdose Trial- CXCR4 PET Tracer - Pharmacokinetics and Pharmacodynamics of [68Ga]Ga-R54, a Radiopharmaceutical Directed Toward CXCR4 in Patients With Advanced Solid Neoplasia. NCT07577206EARLY Phase 11 site๐Ÿ“ Naples National Cancer Institute, Naples ยท Tests: [68Ga]Ga-R54 PET/CT A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Chongqing Precision Biotech Co., Ltd ยท Tests: CEA-targeted CAR-T cells A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPฮฑ-CD47 Pathway, in Solid or Hematological Tumors NCT05892718Phase 18 sites๐Ÿ“ Port Saint Lucie๐Ÿ“ Huntersville๐Ÿ“ Greenville FBD Biologics Limited ยท Tests: HCB101 A Clinical Study of SPH7485 Tablets in the Treatment of Advanced Solid Tumors. NCT06487455Phase 16 sites๐Ÿ“ Changsha๐Ÿ“ Fuzhou๐Ÿ“ Hangzhou Shanghai Pharmaceuticals Holding Co., Ltd ยท Tests: SPH7485 JMT106 Injection in the Treatment of Advanced Solid Tumors NCT07275073Phase 11 site๐Ÿ“ Zhejiang Shanghai JMT-Bio Inc. ยท Tests: JMT106 Injection STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study NCT07269080Phase 11 site๐Ÿ“ Chicago University of Illinois Chicago ยท Tests: Ablative radiation treatment
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