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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Advanced Metastatic Breast Cancer

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment. NCT07062965Phase 3433 sites๐Ÿ“ Anchorage๐Ÿ“ Chandler๐Ÿ“ Gilbert Pfizer ยท Tests: PF-07248144, Fulvestrant, Everolimus, Exemestane Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors NCT07288359Phase 1, Phase 216 sites๐Ÿ“ Atlanta๐Ÿ“ Nashville๐Ÿ“ San Antonio Novartis Pharmaceuticals ยท Tests: GVV858, Fulvestrant, Letrozole PG2 Injection for the Treatment of moderate-to Severe Fatigue in Breast Cancer Patients NCT05440227Phase 21 site๐Ÿ“ Taipei PhytoHealth Corporation ยท Tests: PG2 Lyo. Injection 500mg, Placebo 0.9% normal saline A Study on the Efficacy and Safety of Switching Between Two Targeted Strategies, HP+Chemotherapy and HPy+Chemotherapy, After Treatment Progression in HER-2 Positive Advanced or Metastatic Breast Cancer NCT07455188n/a1 site๐Ÿ“ Zhejiang Zhejiang Cancer Hospital ยท Tests: Antitumor treatment plan A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer. NCT07340424EARLY Phase 11 site๐Ÿ“ Jinan Xiaorong Sun ยท Tests: 225Ac-TR2205 Injection FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer NCT05304962Phase 18 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ Port Saint Lucie Regor Pharmaceuticals Inc. ยท Tests: RGT-419B, RGT-419B in combination with hormonal therapy Study of BEBT-209 in Combination With Fulvestrant Versus Placebo in Combination With Fulvestrant in Patients With HR+/HER2- Locally Advanced or Metastatic Breast Cancer Who Have Progressed After Prior Endocrine Therapy NCT06998108Phase 31 site๐Ÿ“ Beijing BeBetter Med Inc ยท Tests: BEBT-209 capsules, BEBT-209 Placebo capluses, Fulvestrant Injection ARX788 in HER2-positive Metastatic Breast Cancer Patients NCT06663748Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: ARX788 Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer NCT06982521Phase 3243 sites๐Ÿ“ Gilbert๐Ÿ“ Beverly Hills๐Ÿ“ Duarte Relay Therapeutics, Inc. ยท Tests: Zovegalisib, Capivasertib, Fulvestrant The COMPASSION Study NCT06507930NA1 site๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Telehealth Hospice Visits Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) NCT06757634Phase 3239 sites๐Ÿ“ Jonesboro๐Ÿ“ Little Rock๐Ÿ“ Duarte Celcuity Inc ยท Tests: Arm A: Gedatolisib + Palbociclib + Fulvestrant, Arm B: Ribociclib + Fulvestrant, Arm C: Gedatolisib + Palbociclib + Letโ€ฆ First-Line Sacituzumab Govitecan in Advanced Untreated Triple-Negative Breast Cancer Patients. NCT07299409Phase 21 site๐Ÿ“ Vancouver Nathalie Levasseur ยท Tests: Sacituzumab Govitecan (SG) AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer NCT06767527Phase 31 site๐Ÿ“ Beijing Akeso ยท Tests: AK112, Nab-paclitaxel, Placebo A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005Phase 17 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ St Louis Angiex, Inc. ยท Tests: AGX101 Phase II/III Study of SPH4336 Combined With Letrozole vs Placebo Combined With Letrozole in First-line Treatment of Breast Cancer NCT05744687Phase 2, Phase 39 sites๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou๐Ÿ“ Guiyang Shanghai Pharmaceuticals Holding Co., Ltd ยท Tests: SPH4336 Tablets 400mg, SPH4336 Tablets Placebo A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Chongqing Precision Biotech Co., Ltd ยท Tests: CEA-targeted CAR-T cells Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors NCT06666270Phase 12 sites๐Ÿ“ Zhengzhou๐Ÿ“ Shanghai Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd ยท Tests: SYN818 Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients NCT06690840Phase 25 sites๐Ÿ“ Monza๐Ÿ“ Roma๐Ÿ“ Roma European Institute of Oncology ยท Tests: Atezolizumab in combination with Cyclophosphamide and Vinorelbine PARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer NCT05759546Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Fluzoparib, Dalpiciclib, Fulvestrant/AI RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study NCT07030569n/a1 site๐Ÿ“ Milan Fondazione IRCCS Istituto Nazionale dei Tumori, Milano ยท Tests: Trastuzumab deruxtecan (DS-8201a) Entinostat Plus Pyrotinib and Endocrine Therapy in Advanced Triple-Positive Breast Cancer After Trastuzumab Failure NCT07708194Phase 1, Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: entinostat, Pyrotinib, endocrine therapy A Study of BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors NCT06493864Phase 11 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B16D1 A Study of GB491 in Combination With Letrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancer NCT05851014Phase 352 sites๐Ÿ“ Bengbu๐Ÿ“ Hefei๐Ÿ“ Hefei Genor Biopharma Co., Ltd. ยท Tests: GB491 combined with Letrozole, Placebo combined with Letrozole A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors NCT06533332Phase 15 sites๐Ÿ“ Ryde๐Ÿ“ Sydney๐Ÿ“ Westmead EtiraRx Australia Pty Ltd ยท Tests: ERX-315 A Study of MR001 in Patients With Locally Recurrent or Metastatic Advanced Triple-Negative Breast Cancer (TNBC) NCT07208149Phase 1, Phase 21 site๐Ÿ“ Beijing Shenzhen Majory Biotechnology Co., Ltd. ยท Tests: MR001 Bispecific Antibody for Injection A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer NCT07558733Phase 1, Phase 27 sites๐Ÿ“ Los Angeles๐Ÿ“ Lone Tree๐Ÿ“ Springfield Faeth Therapeutics ยท Tests: Serabelisib, Sapanisertib, Fulvestrant A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel The Efficacy and Safety of Utidelone Plus Tirelizumab and Bevacizumab for Advanced or Metastatic Triple-negative Breast Cancer (UTILIZABLE) ๏ผšSingle-arm, Prospective, Open Clinical Study NCT06125080Phase 21 site๐Ÿ“ Wuhan Huihua Xiong ยท Tests: Utidelone, Tirelizumab, Bevacizumab Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer NCT06105684Phase 21 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: Capecitabine Pill
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