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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Refractory Solid Tumors

TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies NCT06484816Phase 11 site๐Ÿ“ Hangzhou Shenzhen TargetRx Co., Ltd. ยท Tests: TGRX-1942 A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Shanghai GV20 Therapeutics ยท Tests: GV20-0251 A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPฮฑ-CD47 Pathway, in Solid or Hematological Tumors NCT05892718Phase 18 sites๐Ÿ“ Port Saint Lucie๐Ÿ“ Huntersville๐Ÿ“ Greenville FBD Biologics Limited ยท Tests: HCB101 Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors NCT07145255Phase 1, Phase 27 sites๐Ÿ“ San Francisco๐Ÿ“ Grand Rapids๐Ÿ“ East Brunswick MBrace Therapeutics ยท Tests: ADC Trial of DFP-14927 in Advanced Solid Tumors NCT03943004Phase 12 sites๐Ÿ“ Los Angeles๐Ÿ“ Houston Delta-Fly Pharma, Inc. ยท Tests: DFP-14927 Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors NCT04803318Phase 21 site๐Ÿ“ Guangzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: Combination of three inhibitors Trametinib, Everolimus and Lenvatinib Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours NCT06430502NA1 site๐Ÿ“ Wuxi Wuxi People's Hospital ยท Tests: Tumor Treatment Vaccine; PD-1/L1 inhibitors Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors NCT06132503Phase 11 site๐Ÿ“ West Valley City Lantern Pharma Inc. ยท Tests: LP-284 JL19001 Injection Alone or in Combination With Standard Therapy in Patients With Advanced Solid Tumors or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma NCT07603479Phase 11 site๐Ÿ“ Beijing Jecho Biopharmaceuticals Co., Ltd. ยท Tests: JL19001, subcutaneous injection, 1 ฮผg/kg, JL19001, subcutaneous injection, 5 ฮผg/kg, JL19001, subcutaneous injection,10 โ€ฆ A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430Phase 1, Phase 213 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ New Haven GV20 Therapeutics ยท Tests: GV20-0251, GV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDAยฎ], GV20-0251 and Pembrolizumab [KEYTRUDAยฎ] Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) NCT05579366Phase 1, Phase 266 sites๐Ÿ“ Phoenix๐Ÿ“ Tucson๐Ÿ“ Los Angeles Genmab ยท Tests: Rina-S, Carboplatin, Bevacizumab, Pembrolizumab, Erythromycin Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors NCT06014658Phase 1, Phase 217 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta MBrace Therapeutics ยท Tests: Antibody-Drug Conjugate GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul GeneMedicine Co., Ltd. ยท Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies NCT07309770Phase 21 site๐Ÿ“ Shanghai Sheng Zhang ยท Tests: SHR-A1811, Trastuzumab Rezetecan Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors NCT06320405Phase 1, Phase 21 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Axatilimab, Biopsy, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging Evaluation of XYA02 in Patients With Advanced Solid Tumors NCT07670312Phase 1, Phase 25 sites๐Ÿ“ Sydney๐Ÿ“ Sydney๐Ÿ“ Melbourne XYone Therapeutics, Inc ยท Tests: XYA02 A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies NCT04678648Phase 13 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ Nashville RasCal Therapeutics, Inc. ยท Tests: RSC-1255 Dose Escalation, RSC-1255 Dose Expansion Prospective Multicenter Study Evaluating Feasibility and Efficacy of Tumor Organoid-based Precision Medicine in Patients With Advanced Refractory Cancers NCT05267912NA11 sites๐Ÿ“ Bordeaux๐Ÿ“ Lille๐Ÿ“ Lyon Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: Biopsy A Study of HDM2005 in Patients With Relapsed/Refractory B-cell Lymphoma and Advanced Solid Tumor NCT06615193Phase 18 sites๐Ÿ“ Zhengzhou๐Ÿ“ Suzhou๐Ÿ“ Suzhou Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. ยท Tests: HDM2005 A Phase I, First in Human Study of CBA-1535, T Cell Engager(5T4/CD3/5T4) in Patients With Advanced Solid Tumors. NCT07016997Phase 12 sites๐Ÿ“ Nagaizumicho๐Ÿ“ Chuo-Ku Chiome Bioscience Inc. ยท Tests: CBA-1535, CBA-1535+Pembrolizumab CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors NCT05410717Phase 11 site๐Ÿ“ Guangzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: Claudin6, GPC3, Mesothelin, or AXL targeting CAR-NK cells A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma NCT05341557Phase 14 sites๐Ÿ“ Chaoyang๐Ÿ“ Cangzhou๐Ÿ“ Tianjin Betta Pharmaceuticals Co., Ltd. ยท Tests: BPI-371153 Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors NCT06234098Phase 1, Phase 29 sites๐Ÿ“ Scottsdale๐Ÿ“ Bakersfield๐Ÿ“ El Segundo Alyssum Therapeutics ยท Tests: AT-1965 Liposome Injection An Engineered Sirpฮฑ Fused to Anti-Pd-L1 And Tgf-ฮฒ Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors NCT06487624Phase 17 sites๐Ÿ“ Greenville๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou FBD Biologics Limited ยท Tests: HCB301 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors NCT07189871Phase 1, Phase 25 sites๐Ÿ“ Dothan๐Ÿ“ Grand Rapids๐Ÿ“ Omaha Radiopharm Theranostics, Ltd ยท Tests: 177Lu-BetaBart, BetaBart + unlabeled BetaBart AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors NCT06911333Phase 1, Phase 23 sites๐Ÿ“ Seongnam-si๐Ÿ“ Seoul๐Ÿ“ Seoul Avelos Therapeutics Inc. ยท Tests: AD1208 First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer NCT06799065Phase 1, Phase 211 sites๐Ÿ“ Aurora๐Ÿ“ Sarasota๐Ÿ“ Detroit Accent Therapeutics ยท Tests: ATX-295, ATX-295 and bevacizumab (or biosimilar) Individualized Neoantigen Therapy with Unusual Radiotherapy Enhancement (iNATURE) NCT06314087Phase 22 sites๐Ÿ“ Shenzhen๐Ÿ“ Shenzhen The University of Hong Kong-Shenzhen Hospital ยท Tests: Placebo + conventional treatment including radiotherapy, Radiation: Radiation Therapy๏ผ›Biological: Personalized tumor peโ€ฆ A Phase I Study of LXP1788 Injection with Advanced Solid Tumors. NCT06883539Phase 12 sites๐Ÿ“ Taichung๐Ÿ“ Tainan LaunXP Biomedical Co., Ltd. ยท Tests: LXP1788 is administered intravenously via Port-A
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