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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Solid Tumor (Phase 1)

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation NCT06908434Phase 11 site๐Ÿ“ Shanghai Changchun GeneScience Pharmaceutical Co., Ltd. ยท Tests: GenSci128 tablets A Study of TY-2699a in Patients With Locally Advanced or Metastatic Solid Tumors NCT05866692Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Jinan TYK Medicines, Inc ยท Tests: TY-2699a VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors NCT06821048Phase 11 site๐Ÿ“ Hangzhou Weijia Fang, MD ยท Tests: Intraperitoneal infusion of FAST CEA-targeted CAR-T TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies NCT06484816Phase 11 site๐Ÿ“ Hangzhou Shenzhen TargetRx Co., Ltd. ยท Tests: TGRX-1942 A Study of MT-4561 in Patients With Various Advanced Solid Tumors NCT06943521Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Columbus Tanabe Pharma America, Inc. ยท Tests: MT-4561 A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies NCT07195916Phase 122 sites๐Ÿ“ Duarte๐Ÿ“ La Jolla๐Ÿ“ Ann Arbor Incyte Corporation ยท Tests: INCA036873 Study of GS-2426 in Participants With Advanced Solid Tumors NCT07601243Phase 16 sites๐Ÿ“ Boston๐Ÿ“ Grand Rapids๐Ÿ“ East Brunswick Gilead Sciences ยท Tests: GS-2426 A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors NCT06311578Phase 110 sites๐Ÿ“ New York๐Ÿ“ Philadelphia๐Ÿ“ Pittsburgh Johnson & Johnson Enterprise Innovation Inc. ยท Tests: JNJ-87704916, Cetrelimab, Standard of Care PD(L)-1 NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors NCT05881525Phase 11 site๐Ÿ“ Chongqing TCRCure Biopharma Ltd. ยท Tests: TC-N201 cells, IL-2, Fludarabine, Cyclophosphamide, Nab-paclitaxel DXP-106 in Solid Tumor Patients. NCT07532018Phase 14 sites๐Ÿ“ Harbin๐Ÿ“ Shanghai๐Ÿ“ Taiyuan Singlomics Biopharmaceuticals Zhuhai Co., Ltd. ยท Tests: DXP-106 Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors NCT07288359Phase 1, Phase 216 sites๐Ÿ“ Atlanta๐Ÿ“ Nashville๐Ÿ“ San Antonio Novartis Pharmaceuticals ยท Tests: GVV858, Fulvestrant, Letrozole A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors NCT05584670Phase 1, Phase 222 sites๐Ÿ“ Newark๐Ÿ“ Iowa City๐Ÿ“ Westwood Sanofi ยท Tests: SAR445877, Cetuximab, ADG126, Bevacizumab, Nivolumab A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours NCT06682780Phase 1, Phase 21 site๐Ÿ“ Shanghai LaNova Medicines Limited ยท Tests: LM-2417, Docetaxel, Toripalimab/Tirelizumab, Carboplatin, Niraparib A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors NCT05932862Phase 116 sites๐Ÿ“ Fountain Valley๐Ÿ“ Jacksonville๐Ÿ“ Orlando Exelixis ยท Tests: XL309, Olaparib A Study of HS-20110 in Participants With Advanced Solid Tumors NCT06892379Phase 18 sites๐Ÿ“ Tamarac๐Ÿ“ Fort Wayne๐Ÿ“ Huntersville Hansoh BioMedical R&D Company ยท Tests: HS-20110 (Phase Ia๏ผšDose escalation ), HS-20110 (Phase Ib:Dose expansion ) Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors NCT06974110Phase 115 sites๐Ÿ“ Phoenix๐Ÿ“ San Diego๐Ÿ“ Tampa MOMA Therapeutics ยท Tests: MOMA-341, Irinotecan, Immunotherapy A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors NCT07469982Phase 11 site๐Ÿ“ Shanghai Shouyao Holdings (Beijing) Co. LTD ยท Tests: SY-9453 Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment NCT07036133Phase 14 sites๐Ÿ“ Cerritos๐Ÿ“ Chicago๐Ÿ“ Detroit Acrotech Biopharma Inc. ยท Tests: Pralatrexate Injection A Clinical Study of SYS6023 in Patients With Advanced Solid Tumors NCT07110883Phase 12 sites๐Ÿ“ Harbin๐Ÿ“ Shanghai CSPC Megalith Biopharmaceutical Co.,Ltd. ยท Tests: SYS6023 Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors NCT06532565Phase 16 sites๐Ÿ“ Palo Alto๐Ÿ“ Boston๐Ÿ“ San Antonio Gilead Sciences ยท Tests: GS-2121, Zimberelimab PM534 Administered Intravenously to Patients With Advanced Solid Tumors NCT05835609Phase 13 sites๐Ÿ“ Barcelona๐Ÿ“ Madrid๐Ÿ“ Madrid PharmaMar ยท Tests: PM534 Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies NCT07098299Phase 110 sites๐Ÿ“ Bay City๐Ÿ“ Clarkston๐Ÿ“ Detroit Barbara Ann Karmanos Cancer Institute ยท Tests: Metformin A Phase 1 Study to Investigate FP008 in Subjects With Advanced Solid Tumors NCT06990698Phase 16 sites๐Ÿ“ Guangzhou๐Ÿ“ Wuhan๐Ÿ“ Nanchang Zhuhai Fapon Biopharma Co., Ltd. ยท Tests: FP008 for injection A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Evaluating the Safety, Tolerability, and Preliminary Anti-tumor Activity of MB0151 in Adult Subjects With Advanced Solid Tumors Expressing Somatostatin Receptors NCT06840821Phase 1, Phase 21 site๐Ÿ“ Jinan Mainline Biosciences (Shanghai) Co., Ltd ยท Tests: MB0151 for injection A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors NCT07814248Phase 13 sites๐Ÿ“ Maumee๐Ÿ“ Portland๐Ÿ“ Fairfax TwoStep Therapeutics, Inc. ยท Tests: TS-104 A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Duarte Seagen, a wholly owned subsidiary of Pfizer ยท Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Shanghai GV20 Therapeutics ยท Tests: GV20-0251 Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001 NCT06410092Phase 13 sites๐Ÿ“ Beijing๐Ÿ“ Chongqing๐Ÿ“ Chengdu Sound Biopharmaceuticals Ltd. ยท Tests: FTL001
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