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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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14 recruiting trials

for Advanced Solid Tumors With KRAS G12C Mutations

A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour NCT06383871Phase 11 site๐Ÿ“ Tianjin Shandong Suncadia Medicine Co., Ltd. ยท Tests: HRS-7058 capsule/ HRS-7058 tablet A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation NCT05410145Phase 1, Phase 252 sites๐Ÿ“ Orange๐Ÿ“ Palo Alto๐Ÿ“ Denver D3 Bio (Wuxi) Co., Ltd ยท Tests: D3S-001, Pembrolizumab, Cisplatin, Carboplatin, Pemetrexed Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation NCT05288205Phase 1, Phase 227 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Allist Pharmaceuticals, Inc. ยท Tests: JAB-21822, JAB-3312 A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation. NCT06008288Phase 231 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Allist Pharmaceuticals, Inc. ยท Tests: JAB-21822 JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration NCT06973564Phase 1, Phase 24 sites๐Ÿ“ Rochester๐Ÿ“ St Louis๐Ÿ“ Cleveland Jacobio Pharmaceuticals Co., Ltd. ยท Tests: JAB-23E73, Cetuximab A Phase I/IIa Study of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration NCT06959615Phase 1, Phase 232 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Jacobio Pharmaceuticals Co., Ltd. ยท Tests: JAB-23E73, JAB-23E73 A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors NCT06244771Phase 1, Phase 226 sites๐Ÿ“ La Jolla๐Ÿ“ Orange๐Ÿ“ San Francisco Frontier Medicines Corporation ยท Tests: FMC-376 A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation NCT07172919Phase 211 sites๐Ÿ“ Fort Myers๐Ÿ“ Houston๐Ÿ“ Randwick Amgen ยท Tests: Sotorasib, Panitumumab A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies NCT06720987Phase 111 sites๐Ÿ“ Phoenix๐Ÿ“ Denver๐Ÿ“ Jacksonville Kumquat Biosciences Inc. ยท Tests: KQB365, Cetuximab, KQB198 Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC NCT06162221Phase 1, Phase 298 sites๐Ÿ“ Gilbert๐Ÿ“ Duarte๐Ÿ“ Irvine Revolution Medicines, Inc. ยท Tests: RMC-6291, RMC-6236, Pembrolizumab, Cisplatin, Carboplatin A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations NCT07629960Phase 1, Phase 216 sites๐Ÿ“ Sarasota๐Ÿ“ Tampa๐Ÿ“ Baton Rouge Blueprint Medicines Corporation ยท Tests: BLU-924 A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation NCT06659341Phase 111 sites๐Ÿ“ Albury๐Ÿ“ Macquarie Park๐Ÿ“ Frankston Bayer ยท Tests: BAY3498264 Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors NCT06128551Phase 1, Phase 256 sites๐Ÿ“ Duarte๐Ÿ“ Orange๐Ÿ“ Sacramento Revolution Medicines, Inc. ยท Tests: Elironrasib, Daraxonrasib
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