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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced or Recurrent Solid Tumors

A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies. NCT07389239Phase 1, Phase 21 site๐Ÿ“ Chicago University of Chicago ยท Tests: Decitabine, Cyclophosphamide Conditioning, NY-ESO-1 TCR/ dnTGFฮฒRII, Aldesleukin Study of ACR-2316 in Specific Advanced Solid Tumors NCT06667141Phase 1, Phase 215 sites๐Ÿ“ Phoenix๐Ÿ“ Beverly Hills๐Ÿ“ Newport Beach Acrivon Therapeutics ยท Tests: ACR-2316 Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors NCT06132503Phase 11 site๐Ÿ“ West Valley City Lantern Pharma Inc. ยท Tests: LP-284 Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors NCT06320405Phase 1, Phase 21 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Axatilimab, Biopsy, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors NCT07022002Phase 21 site๐Ÿ“ Hangzhou Shenyang Sunshine Pharmaceutical Co., LTD. ยท Tests: SSGJ-705, PD-1/L1 inhibitor combined with chemotherapy, SSGJ-705 combined with chemotherapy A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors NCT06465069Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Eli Lilly and Company ยท Tests: LY4052031, Pembrolizumab Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment NCT02029001Phase 27 sites๐Ÿ“ Bordeaux๐Ÿ“ Lyon๐Ÿ“ Lyon Centre Leon Berard ยท Tests: Nilotinib (400 mg BID), Everolimus (10 mg QD), Sorafenib (400 mg BID), Lapatinib (1500 mg QD), Pazopanib (800 mg QD) A Phase I/IIa Study of AL8326 Combined With Toripalimab in the Treatment of Advanced Solid Tumors. NCT07392736Phase 1, Phase 215 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Hunan Advenchen Laboratories, LLC ยท Tests: AL8326 tablets, Toripalimab A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors NCT05270213Phase 114 sites๐Ÿ“ Scottsdale๐Ÿ“ Tucson๐Ÿ“ Palo Alto Riboscience, LLC. ยท Tests: RBS2418, Pembrolizumab, Other approved anti-cancer therapy Safety and Modulation of Adaptive Immunity by Iscadorยฎ Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors NCT06408688Phase 44 sites๐Ÿ“ Baden๐Ÿ“ Basel๐Ÿ“ Liestal University Hospital, Basel, Switzerland ยท Tests: Immune checkpoint inhibitors plus Iscadorยฎ Qu., Immune Checkpoint Inhibitors Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors NCT06234098Phase 1, Phase 29 sites๐Ÿ“ Scottsdale๐Ÿ“ Bakersfield๐Ÿ“ El Segundo Alyssum Therapeutics ยท Tests: AT-1965 Liposome Injection A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors NCT04775485Phase 235 sites๐Ÿ“ San Francisco๐Ÿ“ Washington D.C.๐Ÿ“ Chicago Day One Biopharmaceuticals, Inc. ยท Tests: Tovorafenib First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer NCT06799065Phase 1, Phase 211 sites๐Ÿ“ Aurora๐Ÿ“ Sarasota๐Ÿ“ Detroit Accent Therapeutics ยท Tests: ATX-295, ATX-295 and bevacizumab (or biosimilar) Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial NCT05564377Phase 2484 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Anchorage National Cancer Institute (NCI) ยท Tests: Alpelisib, Binimetinib, Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration Combination of CAR-DC Vaccine and ICIs in Malignant Tumors NCT05631886Phase 11 site๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: TP53-EphA-2-CAR-DC, Abraxane, Cyclophosphamide, anti-PD-1 antibody, Anti-CTLA4 Monoclonal Antibody NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes NCT04945330n/a1 site๐Ÿ“ Multiple Locations Bayer ยท Tests: Larotrectinib (Vitrakvi, BAY2757556) A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST NCT06687070Phase 11 site๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG -2449, PLD A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors NCT06880549Phase 14 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ San Antonio ModernaTX, Inc. ยท Tests: mRNA-4106, Pembrolizumab, mRNA-4200 COAST Therapy in Advanced Solid Tumors and Prostate Cancer NCT05036226Phase 1, Phase 21 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Hydroxychloroquine, Metformin, Sirolimus, Hydroxychloroquine, Metformin, Sirolimus, Dasatanib, Hydroxychloroquine, Metfโ€ฆ Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis NCT05059678NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Best Practice, Educational Intervention, Questionnaire Administration IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer NCT06184035Phase 1, Phase 22 sites๐Ÿ“ Adelaide๐Ÿ“ Melbourne Spago Nanomedical AB ยท Tests: [177Lu]Lu-SN201 Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial NCT04693468Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Axitinib, Crizotinib, Palbociclib Isethionate, Talazoparib Tosylate Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor EVM16 Injection as a Single and Combination With Tislelizumab in Solid Tumors NCT06541639Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Shanghai Peking University ยท Tests: EVM16, Tislelizumab ML-016 in Advanced Cancer With Lung and/or Liver Involvement NCT07723482Phase 1, Phase 23 sites๐Ÿ“ Miranda๐Ÿ“ Wollongong๐Ÿ“ Buderim BrYet US, Inc. ยท Tests: ML-016 Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Baltimore Calico Life Sciences LLC ยท Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deatโ€ฆ A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors NCT06952010Phase 111 sites๐Ÿ“ San Francisco๐Ÿ“ New Haven๐Ÿ“ Tampa Exelixis ยท Tests: XB628, Zanzalintinib
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