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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Alzheimer Disease (AD)

Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's Disease NCT07803055NA1 site๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: blood sampling DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau NCT07142278Phase 11 site๐Ÿ“ Miami Lakes Nuravax, Inc. ยท Tests: DUVAX 200 ยตg, DUVAX 400 ยตg, Placebo (Adjuvant only) Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline NCT05907343NA1 site๐Ÿ“ Austin University of Texas at Austin ยท Tests: Closed-loop TBS, Open-loop TBS Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study NCT06995638NA1 site๐Ÿ“ Newark Rutgers, The State University of New Jersey ยท Tests: Web-based Cognitive Training (with strategy), Web-based Cognitive Training (without strategy) Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function NCT07289061NA1 site๐Ÿ“ Thessaloniki Aristotle University Of Thessaloniki ยท Tests: Positive Psychology Intervention, Treatment as usual (TAU) A Clinical Study Evaluating the Diagnostic Performance and Safety of PET for the Deposition of Aฮฒ Plaques in the Brain of Participants With Normal Cognitive Function, MCI and AD Using [18F]Fluorbetazine Injection NCT07764679Phase 31 site๐Ÿ“ Beijing HTA Co., Ltd. ยท Tests: [18F]Fluorbetazine injection Exploratory Study of Low-Dose Whole-Brain Radiation Therapy With HeLaXON 1X in Patients With Mild Alzheimer's Disease Dementia NCT07863011NA1 site๐Ÿ“ Cheonan ReadyCure Inc. ยท Tests: HeLaXON 1X Low-Dose Radiation Therapy, Sham HeLaXON 1X Procedure Levetiracetam for Persons at Risk for Alzheimer's Disease NCT07477431Phase 22 sites๐Ÿ“ Toronto๐Ÿ“ Toronto Sunnybrook Health Sciences Centre ยท Tests: Levetiracetam (LEV), Placebo A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease NCT07214727Phase 113 sites๐Ÿ“ Montreal๐Ÿ“ Ottawa๐Ÿ“ Toronto Alnylam Pharmaceuticals ยท Tests: ALN-5288, Placebo Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence Models NCT07906769NA1 site๐Ÿ“ Bari Istituti Clinici Scientifici Maugeri SpA ยท Tests: Speech and language Test to support clinical diagnosis ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults NCT07392723Phase 21 site๐Ÿ“ New Brunswick Michal Schnaider Beeri, Ph.D. ยท Tests: Alpha-Linolenic Acid (2.6 g/day), Placebo Control Group Repurposing Siponimod for Alzheimer's Disease NCT06639282Phase 21 site๐Ÿ“ Phoenix St. Joseph's Hospital and Medical Center, Phoenix ยท Tests: Siponimod, Placebo Adapting RDAD for DS NCT07425769NA1 site๐Ÿ“ Kansas City University of Kansas Medical Center ยท Tests: Remote Exercise Sessions, Caregiver Education Sessions The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study NCT05988385NA4 sites๐Ÿ“ Tucson๐Ÿ“ New York๐Ÿ“ New York California Pacific Medical Center Research Institute ยท Tests: Positive airway pressure, Oral appliance therapy, Positional therapy [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD NCT06120049Phase 2, Phase 32 sites๐Ÿ“ Ghent๐Ÿ“ Leuven prof. dr. Koen Van Laere ยท Tests: [18F]-MFBG PET CT, [18F]-FE-PE2I PET CT or PET MRI, [123I]-MIBG SPECT CT, [18F]-MFBG PET dosimetry scans An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease NCT07724132Phase 32 sites๐Ÿ“ Cambridge๐Ÿ“ Chertsey University College, London ยท Tests: Placebo, Atomoxetine, Metformin 1000 mg Oral Tablet Imaging Biomarkers in Preclinical and Symptomatic AD NCT04134923n/a1 site๐Ÿ“ St Louis Tammie L. S. Benzinger, MD, PhD ยท Tests: [11C] Pittsburgh Compound-B (PIB) The Effect of Urolithin A (Mitopureยฎ) on Alzheimer's Disease NCT07842146NA1 site๐Ÿ“ Prague University Hospital, Akershus ยท Tests: Urolithin A, Placebo Control Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD NCT07115238Phase 31 site๐Ÿ“ Beijing Sinotau Pharmaceutical Group ยท Tests: XTR006 A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation NCT05552157Phase 2, Phase 337 sites๐Ÿ“ Birmingham๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Washington University School of Medicine ยท Tests: Remternetug (SC), Matching Placebo (Remternetug) Moving Yourself in Space and Time: MYSTIC NCT07697664NA1 site๐Ÿ“ Atlanta Emory University ยท Tests: Complex Rhythmic Movement Sequences (CRMS) Sessions Evaluate the Concordance Between PET Imaging of [18F]-APN-1607 Injection and Postmortem Brain Tissue Tau Pathology in Individuals With HV and MCI or AD. NCT07752784Phase 31 site๐Ÿ“ Beijing JYAMS PET Research & Development Limited ยท Tests: [18F]-APN-1607 Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers NCT05395624Phase 1, Phase 23 sites๐Ÿ“ San Francisco๐Ÿ“ Stanford๐Ÿ“ Jacksonville Ashvattha Therapeutics, Inc. ยท Tests: 18F-OP-801 Predicting Pre-dementia NCT07516119n/a1 site๐Ÿ“ San Diego Prevention Research Consortium Corp. Assess Fibrin in Brains With AD/ADRD NCT05336695Phase 1, Phase 21 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: PET/MR Imaging, 64Cu-FBP8 Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease NCT07036328NA1 site๐Ÿ“ Amsterdam Willem de Haan ยท Tests: repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation Exploring the Utility of [18F]3F4AP for Demyelination Imaging NCT06999434Phase 11 site๐Ÿ“ New Haven Yale University ยท Tests: [ 18F]3F4AP, [18F]MK6240, [11C]PIB ฮด in Dementia Clinical Trials NCT05592678NA1 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Donepezil Daridorexant for Alzheimer Disease Prevention NCT07213349Phase 21 site๐Ÿ“ Montreal Douglas Mental Health University Institute ยท Tests: Daridorexant 50 mg, Placebo Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging NCT03954899NA1 site๐Ÿ“ Iowa City Natalie Denburg ยท Tests: melatonin, placebo
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