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30 recruiting trials

for Amyloidosis; Systemic

BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis NCT07151690Phase 21 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: anti-BCMA/CD3 bispecific antibody Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis NCT06022939Phase 3117 sites๐Ÿ“ Goodyear๐Ÿ“ Tucson๐Ÿ“ Tucson SWOG Cancer Research Network ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrowโ€ฆ Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: biologic sample preservation procedure, cytology specimen collection procedure Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research NCT07085559EARLY Phase 11 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Metabolically Armed BCMA CAR-T cells. Teclistamab in Previously Treated AL Amyloidosis NCT06935162Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Teclistamab (Tec) DapagliFLOzin in Renal AL Amyloidosis (FLORAL) NCT06420167Phase 21 site๐Ÿ“ Detroit Barbara Ann Karmanos Cancer Institute ยท Tests: Dapagliflozin Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis NCT06699394NA2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Teclistamab (Tec) Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients NCT07266116Phase 1, Phase 227 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing Shanghai Chia Tai Tianqing Pharmaceutical Technology Develoโ€ฆ ยท Tests: TQB2934 injection A Phase II Study to Evaluate the Efficacy and Safety of Teclistamab in Combination With Daratumumab (Tec-Dara) in Newly Diagnosed Multiple Myeloma With Concurrent Light Chain Amyloidosis (MM+AL). NCT07638683Phase 21 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Teclistamab Investigating the Pathogenic Role of N-glycosylation in AL Amyloidosis: Molecular Bases, Diagnosis, and Treatment NCT07448779n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial NCT05898646Phase 22 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Bone Marrow Aspiration, Daratumumab, Echocardiography Test, Questionnaire Administration, X-Ray Imaging A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA) NCT06205953n/a6 sites๐Ÿ“ Heidelberg๐Ÿ“ Pavia๐Ÿ“ Utrecht Fondazione IRCCS Policlinico San Matteo di Pavia Observational Epidemiological Study of Patients Suffering From Systemic Amyloidosis NCT06866912n/a1 site๐Ÿ“ Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource NCT01408225n/a1 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: tissue banking SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders NCT07850284n/a1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Non-Interventional Study The Italian Transthyretin Amyloidosis Web-Network NCT05444920n/a30 sites๐Ÿ“ Legnano๐Ÿ“ Orbassano๐Ÿ“ Ancona Fondazione IRCCS Policlinico San Matteo di Pavia Rapid dFLC Response Predict CHR in AL Amyloidosis NCT06627309n/a8 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Dara IV, Bortezomib (drug), Dexamethasone, Cyclophosphamide (CTX), Dara SC BE.Amycon Biobank & Data Registry UZ Leuven NCT07172243n/a2 sites๐Ÿ“ Leuven๐Ÿ“ Leuven Universitaire Ziekenhuizen KU Leuven Daratumumab for Patients With Light Chain Amyloidosis NCT06376214NA1 site๐Ÿ“ Nanjing Nanjing University School of Medicine ยท Tests: Dratumumab / Hyaluronidase Injection [Darzalex Faspro], Pomalidomide 4 MG, autologous stem cell transplantation (ASCT) Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis NCT07079423Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Teclistamab (Tec) Optimize First-line Treatment for AL Amyloidosis With t (11; 14) NCT06192979NA7 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Jin Lu, MD ยท Tests: Daratumumab, Bortezomib, Dexamethasone, Venetoclax [18F]FT8 PET Imaging in Immunoglobulin Light Chain Amyloidosis NCT07232459n/a3 sites๐Ÿ“ Hefei๐Ÿ“ Qingdao๐Ÿ“ Tianjin Tianjin Medical University ยท Tests: [18F]FT8 Registry of Older Patients With Cancer NCT01137825n/a7 sites๐Ÿ“ Boone๐Ÿ“ Chapel Hill๐Ÿ“ Greenville UNC Lineberger Comprehensive Cancer Center Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis NCT07250269Phase 19 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Gracell Biotechnologies (Shanghai) Co., Ltd. ยท Tests: GC012F Injection Clinical Study for AL-CM NCT04924998n/a1 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: current treatment of AL-CM One Gene, Two Diseases: the Pathologic Role of IGLV1-44 in AL Amyloidosis and POEMS NCT07448935n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis. NCT07081646Phase 1, Phase 218 sites๐Ÿ“ Phoenix๐Ÿ“ San Francisco๐Ÿ“ Tampa Alexion Pharmaceuticals, Inc. ยท Tests: AZD0120 A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion NCT06158854Phase 1, Phase 223 sites๐Ÿ“ Miami๐Ÿ“ Boston๐Ÿ“ Rochester AbbVie ยท Tests: ABBV-383 (Etentamig) Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis NCT06569147Phase 1, Phase 25 sites๐Ÿ“ New Haven๐Ÿ“ Boston๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Elranatamab Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis NCT05145816Phase 1, Phase 23 sites๐Ÿ“ Nashville๐Ÿ“ Dallas๐Ÿ“ Salt Lake City University of Texas Southwestern Medical Center ยท Tests: Belantamab mafodotin 2.5 mg/kg (8 weeks), Belantamab mafodotin 1.9 mg/kg (8 weeks), Belantamab mafodotin 1.4 mg/kg (12 โ€ฆ
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