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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for BRCA1 Mutation

Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries NCT05769517n/a1 site📍 Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: Germinal BRCA BRCA Mutation Carriers' Platform a Multicenter Study NCT07253051n/a40 sites📍 Avellino📍 Aviano📍 Bari Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: Registration of clinical datas in the platform A Bidirectional Cohort Study on Prophylactic Resection Surgery in Populations at Moderate-to-High Risk for Hereditary Ovarian Cancer NCT07532434n/a1 site📍 Beijing Peking University Third Hospital An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results NCT05420064NA8 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care Carboplatin or Olaparib for BRcA Deficient Prostate Cancer NCT04038502Phase 218 sites📍 West Los Angeles📍 Aurora📍 Washington D.C. VA Office of Research and Development · Tests: Carboplatin, Olaparib Cognitive Behavioral Therapy for Fear of Cancer Recurrence in Women With BRCA1/2 Gene NCT06817694NA1 site📍 Québec CHU de Quebec-Universite Laval · Tests: Cognitive-behavioral group therapy Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation NCT04890613Phase 18 sites📍 Santa Monica📍 Tampa📍 Boston Senhwa Biosciences, Inc. · Tests: CX-5461 Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations NCT00823654n/a8 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Blood draw and questionnaires, Blood draw and questionnaires Prophylactic Irradiation to the Contralateral Breast for BCAs Patients NCT04960839NA8 sites📍 Jiangxi📍 Shanghai📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: Prophylactic contralateral breast irradiation Pancreas Registry and High Risk Registry NCT02775461n/a2 sites📍 New York📍 New York Icahn School of Medicine at Mount Sinai Prostate Cancer Genetic Risk Evaluation and Screening Study NCT05129605n/a1 site📍 Boston Massachusetts General Hospital · Tests: Prostate cancer screening Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer NCT07436312NA3 sites📍 Avignon📍 Rennes📍 Villejuif Gustave Roussy, Cancer Campus, Grand Paris · Tests: educational workshop on nutrition + additional intervention on UPF tool and how to use it Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer NCT06580314Phase 3695 sites📍 Birmingham📍 Anchorage📍 Anchorage NRG Oncology · Tests: Bevacizumab, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Olaparib PARPi or Capecitabine Combined With PD-1 Inhibitors as Adjuvant Therapy in High-risk TNBC NCT06533384Phase 31 site📍 Guangzhou Guangdong Provincial People's Hospital · Tests: As per the germline BRCA1/2 mutation status, the selection of either Fuzuloparib or capecitabine in combination with Ca… Registry of Subjects at Risk of Pancreatic Cancer NCT04095195n/a4 sites📍 Rozzano📍 Peschiera del Garda📍 Milan Associazione Italiana per lo Studio del Pancreas · Tests: MRCP, Endoultrasonography Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer NCT06488378Phase 12 sites📍 Boston📍 Rochester Dana-Farber Cancer Institute · Tests: Axatilimab, Olaparib Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy NCT06972719NA2 sites📍 Chapel Hill📍 Durham Duke University · Tests: Experimental Arm, SOC Arm Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer NCT06380751Phase 3306 sites📍 Gilbert📍 Fountain Valley📍 Glendale AstraZeneca · Tests: Saruparib (AZD5305), Camizestrant, Abemaciclib, Ribociclib, Palbociclib A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer NCT04251052NA574 sites📍 Birmingham📍 Anchorage📍 Anchorage NRG Oncology · Tests: Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection, Magnetic Resonance Imaging,… Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations NCT02705846n/a1 site📍 Sutton Institute of Cancer Research, United Kingdom · Tests: Observation of treatment outcomes via Questionnaire Development and Validation of an Ovarian Cancer Risk Prediction Model for Family Members of Ovarian Cancer Probands NCT07039552n/a1 site📍 Beijing Peking University Third Hospital · Tests: risk-reducing salpingo-oophorectomy (RRSO) APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation NCT04858334Phase 2456 sites📍 Anchorage📍 Anchorage📍 Anchorage National Cancer Institute (NCI) · Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Olaparib, Placebo Administration A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors. NCT07356453Phase 18 sites📍 Palo Alto📍 San Francisco📍 Grand Rapids FoRx Therapeutics AG · Tests: FORX-428 The Cancer of the Pancreas Screening-5 CAPS5)Study NCT02000089Phase 39 sites📍 New Haven📍 Baltimore📍 Boston Johns Hopkins University · Tests: Secretin, MRI, Tumor marker gene test with CA19-9 A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance NCT07321015Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Fluzoparib Monotherapy Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk NCT02478892n/a1 site📍 Philadelphia Abramson Cancer Center at Penn Medicine · Tests: Collection of data from endoscopic ultrasound or MRI/MRCP of the abdomen, Blood sample collection for research Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation NCT05806515Phase 2133 sites📍 Anchorage📍 Anchorage📍 Anchorage SWOG Cancer Research Network · Tests: Biospecimen Collection, Carboplatin, Chest Radiography, Computed Tomography, Magnetic Resonance Imaging A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study) NCT07292246NA1 site📍 Glyfada Vasileios Kalles · Tests: Endoscopic nipple sparing mastectomy, HandX endoscopic instrument Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome NCT04431024n/a1 site📍 Bethesda National Cancer Institute (NCI) Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer. NCT05378204NA25 sites📍 Bordeaux📍 Caen📍 Clermont-Ferrand Institut Claudius Regaud · Tests: Main study:, Sub-study:
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