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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Beta Thalassemia Major Anemia

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants NCT03937817n/a1 site๐Ÿ“ Bethesda National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT NCT01962415Phase 21 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: Hydroxyurea, Alemtuzumab, Fludarabine, Melphalan, Thiotepa Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease NCT02675959Phase 24 sites๐Ÿ“ Los Angeles๐Ÿ“ Gainesville๐Ÿ“ Valhalla New York Medical College ยท Tests: Defibrotide Long-term Follow-up Study of BRL-101 for TDT NCT06298630n/a7 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Shenzhen Bioray Laboratories ยท Tests: Assessments A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials NCT04064060Phase 3143 sites๐Ÿ“ Los Angeles๐Ÿ“ Oakland๐Ÿ“ Stanford Celgene ยท Tests: Luspatercept Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (ฮฒ)-Thalassemia NCT04143724Phase 226 sites๐Ÿ“ Los Angeles๐Ÿ“ New York๐Ÿ“ Guangzhou Celgene ยท Tests: ACE-536 A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or ฮฒ-thalassemia NCT06073860n/a2 sites๐Ÿ“ Seoul๐Ÿ“ Seoul Bristol-Myers Squibb ยท Tests: Luspatercept Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe ฮฒ-Hemoglobinopathies NCT06647979Phase 11 site๐Ÿ“ Boston Daniel Bauer ยท Tests: autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoprotein, Sequenโ€ฆ AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion NCT04099966Phase 21 site๐Ÿ“ Valhalla Mitchell Cairo ยท Tests: alpha beta depletion International Registry of Patients With Alpha Thalassemia NCT04872179n/a1 site๐Ÿ“ San Francisco University of California, San Francisco Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent ฮฒ-Thalassemia and Severe Sickle Cell Disease NCT05477563Phase 36 sites๐Ÿ“ New York๐Ÿ“ Charlotte๐Ÿ“ Nashville Vertex Pharmaceuticals Incorporated ยท Tests: CTX001 Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease NCT01245179Phase 11 site๐Ÿ“ Augusta Abdullah Kutlar ยท Tests: panobinostat MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam A Study of Participants with ฮ’-Thalassemia Treated with Betibeglogene Autotemcel NCT06271512n/a6 sites๐Ÿ“ Oakland๐Ÿ“ Palo Alto๐Ÿ“ Minneapolis Genetix Biotherapeutics Inc. ยท Tests: No Intervention Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: data collection A Multiple Ascending Dose Study of 9MW3011 in Patients With Non-transfusion-dependent ฮฒ-thalassemia NCT06772766Phase 12 sites๐Ÿ“ Nanning๐Ÿ“ Haikou Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW3011, 9MW3011 placebo Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia NCT06490627Phase 21 site๐Ÿ“ Karachi National Institute of Blood and Marrow Transplant (NIBMT), โ€ฆ ยท Tests: Thalidomide, Thalidomide T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias NCT03653338Phase 1, Phase 21 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab Clinical Study of Super Transplantation in the Treatment of Severe ฮฒ-thalassemia NCT06734520NA2 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Guangzhou Women and Children's Medical Center ยท Tests: super-transplantation in 3 severe ฮฒ -thalassemia pediatric patients. A Trial Testing SP-420 in Subjects With Transfusion-dependent ฮฒ-thalassemia or Low-risk Myelodysplastic Syndromes NCT05693909Phase 21 site๐Ÿ“ Copenhagen Pharmacosmos A/S ยท Tests: SP-420 RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs) NCT06213402n/a1 site๐Ÿ“ Barcelona Hospital Universitari Vall d'Hebron Research Institute ยท Tests: Data collection from EHR. A Long-term Follow-up Study in Participants Who Received CS-101 NCT06479616NA1 site๐Ÿ“ Shanghai Children's Hospital of Fudan University ยท Tests: CS-101 A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent ฮฒ-Thalassemia [TDT] NCT05762510EARLY Phase 11 site๐Ÿ“ Nanning First Affiliated Hospital of Guangxi Medical University ยท Tests: GMCN-508B (LentiRed) A Study of Immune Suppression Treatment for People With Sickle Cell Disease or ฮฒ-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) NCT05736419Phase 26 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Fludarabine, Cyclophosphamide, Tacrolimus, Mycophenolate Mofetil, Rabbit ATG Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta Thalassemia NCT07673302NA1 site๐Ÿ“ Rawalpindi Riphah International University ยท Tests: Thalidomide, Hydroxy Urea Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors NCT07599176Phase 1, Phase 21 site๐Ÿ“ Bethesda National Heart, Lung, and Blood Institute (NHLBI) ยท Tests: Total Body Irradiation, Alemtuzumab, Abatacept, Research blood draw Transfusion-Related Changes in Oxidative Stress Biomarkers in Neonates NCT07672275n/a1 site๐Ÿ“ Graz Medical University of Graz ยท Tests: Peroxide analysis-TOC Omnignostica Forschungs GmbH, Near Infrared Imaging Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent ฮฒ-Thalassemia NCT07884773Phase 31 site๐Ÿ“ Peshawar Khyber Medical University Peshawar ยท Tests: Thalidomide, Danazol, Prednisolone Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients NCT06219239NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: KL003 cell injection Drug Product Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major NCT07112703NA1 site๐Ÿ“ Zagazig Rawan Mohammed Khairy Mostafa Elsawy ยท Tests: Incentive spirometer exercises, Diaphragmatic breathing, Pursed lip breathing:, Costal breathing exercises
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