🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Bipolar I Disorder

Exercise and Olanzapine-samidorphan NCT06740890Phase 41 site📍 New York New York State Psychiatric Institute · Tests: Olanzapine-samidorphan + exercise Children's Bipolar Network Treatment Trial I NCT05427123n/a4 sites📍 Los Angeles📍 Aurora📍 Pittsburgh University of California, Los Angeles · Tests: Medication or psychosocial treatment Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients NCT06372964Phase 368 sites📍 Dothan📍 Little Rock📍 Anaheim Intra-Cellular Therapies, Inc. · Tests: Lumateperone, Placebo Socio-cognitive and Biological Responses to Maltreatment NCT07101107n/a1 site📍 Innsbruck Medical University Innsbruck FOCUS Bipolar: Families Opening Conversations for Understanding Signs NCT07622927n/a1 site📍 Dallas University of Texas Southwestern Medical Center · Tests: Co-design Workshop (Observational Procedure), Alpha Testing (Observational Procedure), Beta Testing (Observational Proc… Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder NCT07213466Phase 41 site📍 Rochester Mayo Clinic · Tests: Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination) CLOZAPINE Response in Biotype-1 NCT04580134Phase 45 sites📍 Hartford📍 Athens📍 Chicago University of Texas Southwestern Medical Center · Tests: clozapine, risperidone NMDA Receptor Modulation for the Treatment of Bipolar I Disorder NCT05977023Phase 21 site📍 Taichung China Medical University Hospital · Tests: NMDAE, Placebo Cap ALTO-100 in Bipolar Disorder With Depression (BD-D) NCT06656416Phase 268 sites📍 Birmingham📍 Chandler📍 Phoenix Alto Neuroscience · Tests: ALTO-100, Placebo Safety and Feasibility of DBS for Bipolar Depression NCT07745374NA1 site📍 New York Icahn School of Medicine at Mount Sinai · Tests: Medtronic Percept PC DBS system A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder NCT06696755Phase 233 sites📍 Huntsville📍 Chandler📍 Tucson AbbVie · Tests: Icalcaprant, Placebo for Icalcaprant Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. NCT07494305Phase 226 sites📍 Bentonville📍 Little Rock📍 Bellflower LB Pharmaceuticals Inc. · Tests: LB-102, Placebo Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder NCT05303064Phase 347 sites📍 Dothan📍 Little Rock📍 Encino Alkermes, Inc. · Tests: OLZ/SAM, Olanzapine Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study NCT06831435NA1 site📍 Beijing Peking University · Tests: a digital product based on CBT Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services NCT06740383n/a6 sites📍 Hartford📍 Athens📍 Chicago Beth Israel Deaconess Medical Center A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) NCT06951711Phase 385 sites📍 Little Rock📍 Rogers📍 Culver City Bristol-Myers Squibb · Tests: KarXT, Placebo Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) NCT07569198Phase 21 site📍 Toronto Joshua Rosenblat · Tests: Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT NCT07211750NA1 site📍 Leuven KU Leuven · Tests: integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidi… A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder. NCT04777357Phase 381 sites📍 Bentonville📍 Anaheim📍 Beverly Hills AbbVie · Tests: Cariprazine, Placebo Decoding Emotional Dynamics in Bipolar Disorder NCT07221864NA1 site📍 Tulsa Laureate Institute for Brain Research, Inc. · Tests: Think and Regulate Affective State Task Norwegian Mental Illness Heart Health Study NCT07085923NA1 site📍 Oslo Madeleine Elisabeth Angelsen · Tests: Lifestyle Intervention A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder NCT06951698Phase 374 sites📍 Bentonville📍 Little Rock📍 Anaheim Bristol-Myers Squibb · Tests: KarXT, Placebo The Bipolar Lithium Imaging Scan Study. NCT06134349n/a1 site📍 Leiden Leiden University Medical Center · Tests: Lithium MR imaging Melatonin and Response to Lithium NCT05878730n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: urine collection, Level of Proteins, Level of mRNA and miRNA, Level of plasmatic and intraerythrocytic lithium SYNCED - SYNChronized Eating in Bipolar Depression Study NCT06560957NA1 site📍 Ottawa University of Ottawa · Tests: Time restricted eating, Eating ad libitum with nutritional counselling Feasibility and Preliminary Results of the Efficacy of Blue-Blocking Glasses on Manic Symptoms in Bipolar Disorder NCT07194278NA1 site📍 Paris Centre Hospitalier St Anne · Tests: Blue-blocking glasses An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania NCT07288320Phase 211 sites📍 Little Rock📍 Cerritos📍 Garden Grove Neurocrine Biosciences · Tests: NBI-1117568, Placebo Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II. NCT07412132Phase 31 site📍 São Paulo University of Sao Paulo · Tests: Lacosamide, Placebo Safety and Tolerability of Open-Labeled Iloperidone in Adolescents NCT05648591Phase 411 sites📍 Dothan📍 Little Rock📍 Denver Vanda Pharmaceuticals · Tests: Iloperidone Biocollection on Peripheral Inflammation NCT05934474n/a1 site📍 Nantes Nantes University Hospital · Tests: Peripheral venipuncture blood sampling, as part of standard care procedures, Interview with a psychiatrist
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy