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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Brain Gliomas

Key Longitudinal Associations With Risk and Glioblastoma Outcomes NCT06625684n/a1 site📍 Durham Duke University A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion NCT04655404EARLY Phase 121 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Larotrectinib, Larotrectinib surgical Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures NCT07493447EARLY Phase 11 site📍 Nashville Eben Rosenthal · Tests: Panitumumab-IRDye800 NK Cell Therapy for Malignant Solid Brain Tumors NCT07552233NA4 sites📍 Beijing📍 Qinhuangdao📍 Zhengzhou Peking University Third Hospital · Tests: Autologous NK cells rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG NCT04943848Phase 13 sites📍 Orange📍 Chicago📍 Boston Ann & Robert H Lurie Children's Hospital of Chicago · Tests: rHSC-DIPGVax, Balstilimab, Zalifrelimab AI-driven Processing and Analysis of Glioma Imaging Data NCT07703761n/a1 site📍 Trento Università degli Studi di Trento · Tests: AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization… Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: MRI and advanced MRI sequences Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site📍 China The Third Affiliated hospital of Zhejiang Chinese Medical U… · Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors NCT07675070n/a1 site📍 Tehran NanoAlvand · Tests: temozolomide Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells NCT06059690Phase 1, Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: pH Measurement of in vivo tissue A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients NCT06496971Phase 32 sites📍 Taipei📍 Taoyuan NaviFUS Corporation · Tests: Bevacizumab, Microbubble, Low-Intensity Focused Ultrasound Vascular Signature Mapping of Brain Tumor Genotypes NCT05274919n/a2 sites📍 Leiden📍 Rotterdam Leiden University Medical Center · Tests: Philips Achieva 7T MRI, X-ray (optional), Additional contrast injection, Question list Bevacizumab Neoadjuvant Therapy for New High-grade Gliomas in the Brain NCT06747728NA1 site📍 Zhengzhou The First Affiliated Hospital of Zhengzhou University · Tests: Bevacizumab Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour NCT05230758Phase 320 sites📍 New Lambton Heights📍 Westmead📍 Adelaide Donald Mabbott · Tests: Metformin hydrochloride (HCl) 500mg tablet, Placebo Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor NCT05590689Phase 1, Phase 21 site📍 Münster Universität Münster · Tests: Gliolan, Radiodynamic therapy Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas NCT07110246Phase 212 sites📍 Birmingham📍 San Francisco📍 Washington D.C. University of California, San Francisco · Tests: Dabrafenib, Trametinib, Magnetic Resonance Imaging (MRI), Specimen Collection, Optional Lumbar puncture Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China NCT05672043n/a1 site📍 Beijing Beijing Tiantan Hospital A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma NCT07464925Phase 13 sites📍 Tampa📍 Chicago📍 New York Tetragon Biosciences Ltd · Tests: GLIX1 Modified CV Regimen in Optic Pathway Glioma NCT05278715Phase 21 site📍 Beijing Beijing Sanbo Brain Hospital · Tests: Carboplatin, Vincristine, Recombinant human endostatin Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors NCT07236840n/a1 site📍 Mumbai Tata Memorial Centre · Tests: Neurological assessment Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion NCT06333899EARLY Phase 118 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Lorlatinib, Lorlatinib with chemotherapy1, Lorlatinib with chemotherapy 2, Lorlatinib post Radiation C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) NCT04099797Phase 11 site📍 Houston Baylor College of Medicine · Tests: C7R-GD2.CART cells (IV and ICV infusion), C7R-GD2.CART cells (IV and ICV infusion) Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial NCT06319027Phase 218 sites📍 Birmingham📍 Los Angeles📍 Jacksonville ECOG-ACRIN Cancer Research Group · Tests: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, Fluciclovine F18, Gadolinium-Chelate, Magnetic Res… 000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations NCT05588141Phase 1, Phase 22 sites📍 Jacksonville📍 Bethesda National Cancer Institute (NCI) · Tests: Zotiraciclib Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients NCT03849430n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion NCT05990244NA1 site📍 Shenyang Shengjing Hospital · Tests: Magnetic Resonance Elastography, Assessment and Recording Non-invasive Glioma Characterization Through Molecular Imaging NCT03684109NA1 site📍 Miami University of Miami · Tests: 3T MRI Scanner Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site📍 New York Jeffrey N. Bruce · Tests: Topotecan
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