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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Brain Malformation

An Exploratory Clinical Trial of VGN-R08b in Patients With Type II Gaucher Disease NCT06272149EARLY Phase 11 site๐Ÿ“ Shanghai Xinhua Hospital, Shanghai Jiao Tong University School of Meโ€ฆ ยท Tests: VGN-R08b SENIOR: Stroke Prevention in the Elderly by Patent Foramen Ovale closuRe vs Anticoagulation NCT07479147n/a3 sites๐Ÿ“ Taichung๐Ÿ“ Taipei๐Ÿ“ Taipei Taichung Veterans General Hospital ยท Tests: PFO closure, Medication An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou๐Ÿ“ Hangzhou Beijing Tide Pharmaceutical Co., Ltd ยท Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Comparing Two PFO Closure Devices in Adults With Previous Stroke or TIA NCT07380490NA1 site๐Ÿ“ Bad Oeynhausen Giuseppe Tarantini ยท Tests: PFO Closure procedure A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease NCT06328608Phase 2, Phase 312 sites๐Ÿ“ Phoenix๐Ÿ“ Atlanta๐Ÿ“ Iowa City Chiesi Farmaceutici S.p.A. ยท Tests: PRX-102 1 mg/kg every two weeks Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site๐Ÿ“ Sioux Falls Sanford Health IMarkHD: in Vivo Longitudinal Imaging of HD Pathology NCT03434548n/a1 site๐Ÿ“ London King's College London ยท Tests: PET imaging, Multi-modal MRI imaging A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD) NCT06192576n/a6 sites๐Ÿ“ Chicago๐Ÿ“ Cincinnati๐Ÿ“ Columbus Sanofi ยท Tests: Olipudase alfa 18F-DOPA II - PET Imaging Optimization NCT04706910Phase 31 site๐Ÿ“ Edmonton University of Alberta ยท Tests: 18F-DOPA, Furosemide Injection Autosomal Dominant Spinocerebellar Ataxias and Social Cognition NCT07099651NA1 site๐Ÿ“ Angers University Hospital, Angers ยท Tests: tests The FBRI VTC Neuromotor Research Clinic NCT03325946n/a1 site๐Ÿ“ Roanoke Virginia Polytechnic Institute and State University ยท Tests: ACQUIRE Therapy Ocular Characteristics in Patients With Craniosynostosis NCT06928727n/a1 site๐Ÿ“ Amiens Centre Hospitalier Universitaire, Amiens Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells NCT06967831n/a2 sites๐Ÿ“ Dรผsseldorf๐Ÿ“ Berlin Charite University, Berlin, Germany ยท Tests: skin biopsy, generation of iPSCs, blood drawing, off-label compassionate drug use A Clinical Study on the Treatment of Wilson Disease With ATP7B mRNA/LNP (DSL101) NCT07240896EARLY Phase 11 site๐Ÿ“ Hefei DSciLab Co., Ltd. ยท Tests: Group 1: DSL101 Low dose, Group 2: DSL101 Medium dose, Group 3: DSL101 High dose A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria NCT07241234Phase 15 sites๐Ÿ“ Indianapolis๐Ÿ“ Pittsburgh๐Ÿ“ Dallas Agios Pharmaceuticals, Inc. ยท Tests: AG-181 KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases NCT06451757Phase 310 sites๐Ÿ“ Boston๐Ÿ“ Cleveland๐Ÿ“ Houston Khondrion BV ยท Tests: Sonlicromanol, Placebo A Long-Term Study of JNT-517 in Participants With Phenylketonuria NCT06628128Phase 312 sites๐Ÿ“ Gainesville๐Ÿ“ Tampa๐Ÿ“ Portland Otsuka Pharmaceutical Development & Commercialization, Inc. ยท Tests: JNT-517 Natural History of Wilson Disease NCT03334292n/a6 sites๐Ÿ“ New Haven๐Ÿ“ Orlando๐Ÿ“ Houston Yale University Vasculitis Pregnancy Registry NCT02593565n/a1 site๐Ÿ“ Tampa University of Pennsylvania ยท Tests: Online questionnaires Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder NCT05499741NA1 site๐Ÿ“ Los Angeles University of California, Los Angeles ยท Tests: Forehead Temperature-Regulating Therapy Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome NCT06909656NA1 site๐Ÿ“ Bordeaux University Hospital, Bordeaux ยท Tests: Multimodal electrophysiological recordings Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia NCT06692296NA1 site๐Ÿ“ Pieve di Soligo IRCCS Eugenio Medea ยท Tests: Balance training over stabilometric platform, Balance training by means of conventional rehabilitation Taiwan Associated Genetic and Nongenetic Small Vessel Disease NCT05473637n/a1 site๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: MRI Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease NCT07154394n/a1 site๐Ÿ“ Essen University Hospital, Essen Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia NCT05302271Phase 11 site๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: AAVrh.10hFXN, serotype rh.10 adeno-associated virus (AAV) gene transfer vector expressing the cDNA coding for human FXNโ€ฆ Retinal Imaging in Neurodegenerative Disease NCT03233646n/a1 site๐Ÿ“ Durham Duke University ยท Tests: Retinal and Choroidal Imaging Longitudinal Impact of Stressors in Adults With Tourette Syndrome NCT04851678n/a1 site๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: None - observational study Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China NCT04572568n/a1 site๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: Multi-disciplinary assessment Clinical Course Of Disease In Participants With FA-CM NCT06865482n/a19 sites๐Ÿ“ La Jolla๐Ÿ“ Tampa๐Ÿ“ Indianapolis Lexeo Therapeutics Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity NCT07674290Phase 41 site๐Ÿ“ Essen Tom Hรผhne ยท Tests: Setmelanotide
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