🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Chronic Obstructive Pulmonary Disease Severe

CLEAR Model for Predicting Ventilatory Liberation in Severe COPD NCT07579052n/a1 site📍 Asyut Assiut University Effect of HIgh-flow Therapy in Long-term Oxygen Therapy NCT06247397NA2 sites📍 Karlskrona📍 Örebro Skane University Hospital · Tests: Added high-flow oxygen therapy, Standard care Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo NCT07069829n/a36 sites📍 Buenos Aires📍 La Plata📍 Mar del Plata AstraZeneca Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation NCT06959095Phase 3281 sites📍 Bakersfield📍 Modesto📍 Newport Beach GlaxoSmithKline · Tests: Depemokimab, Placebo Deployment o the Multidisciplinary Prospective Cohort Imminent NCT04334031NA1 site📍 Lille University Hospital, Lille · Tests: Biobanking with genetic analysis, SF-12 questionnaire A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006) NCT06883305Phase 3305 sites📍 Foley📍 Mobile📍 Sheffield AstraZeneca · Tests: Tezepelumab, Placebo A Clinical Trial to Evaluate the Efficacy and Safety of HRS-9821 Inhalation Suspension in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease NCT07640451Phase 21 site📍 Shanghai Guangdong Hengrui Pharmaceutical Co., Ltd · Tests: HRS-9821 Inhalation Suspension, HRS-9821 Placebo Inhalation Suspension Multidisciplinary Management of Severe COPD NCT04860375NA1 site📍 Gothenburg Vastra Gotaland Region · Tests: Multidisciplinary patient care, Standard care Unilateral vs. Bilateral Lung Volume Reduction Surgery NCT07731958NA1 site📍 Copenhagen Copenhagen University Hospital, Rigshospitalet · Tests: Unilateral LVRS, Bilateral LVRS Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD) NCT07509606NA1 site📍 Tainan National Cheng Kung University · Tests: Whole body vibration This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization NCT07587658Phase 41 site📍 Mullica Hill Regeneron Pharmaceuticals · Tests: dupilumab, Placebo This is a Non-interventional, Study to Assess Demographic Characteristics and Patient Reported Outcomes in China Patients With SEA Treated With Benralizumab NCT06862206n/a36 sites📍 Anhui📍 Anning📍 Beijing AstraZeneca · Tests: benralizumab Evaluation of Patients With Immune Function Abnormalities NCT00128973n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) NCT07759245Phase 2127 sites📍 Birmingham📍 Newport Beach📍 San Diego Eli Lilly and Company · Tests: Brenipatide, Placebo, Standard of Care A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema NCT06152107NA9 sites📍 Zhengzhou📍 Beijing📍 Chengdu Shanghai Chest Hospital · Tests: BTVA treatment plus optimal medical therapy (GOLD guidelines) A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK) NCT07116031Phase 235 sites📍 Los Angeles📍 Washington D.C.📍 Atlanta Sanofi · Tests: Belumosudil, Belumosudil Prospective and Multicentric Cohort Study of Severe and Very Severe Chronic Obstructive Pulmonary Disease (COPD) in Brazil (SCOPe). NCT06724315n/a1 site📍 São Paulo Hospital Israelita Albert Einstein A Trial of the Implantable Artificial Bronchus 50 Flex in Patients With Severe Emphysema NCT07086339NA2 sites📍 Limoges📍 Groningen Pulmair Medical, Inc. · Tests: Implantable pulmonary stent A Phase II Study of CM326 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease NCT07418736Phase 21 site📍 Beijing CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · Tests: CM326 dose 1, CM326 dose 2, Placebo Effect of IMT in Patients After Acute Exacerbations of COPD NCT07213128NA12 sites📍 Aalst📍 Anderlecht📍 Brussels KU Leuven · Tests: Training A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius) NCT07646587Phase 232 sites📍 Los Angeles📍 Jacksonville📍 Miami Lakes Windward Bio · Tests: WIN378, Placebo Zephyr Valve Japan Post-Marketing Surveillance NCT06332885n/a17 sites📍 Aichi📍 Gifu📍 Kanagawa Pulmonx Corporation · Tests: Zephyr Endobronchial Valve A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease NCT07082738Phase 2367 sites📍 Birmingham📍 Glendale📍 Phoenix AstraZeneca · Tests: AZD6793, Placebo Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease NCT06985225n/a1 site📍 Kansas City University of Kansas Medical Center · Tests: Hyperpolarized 129 Xenon Study That Will Evaluate the Brazilian Population With COPD. NCT06780046n/a10 sites📍 Aparecida de Goiânia📍 Bahia📍 Belém AstraZeneca COPD Flare-Up Clinic After Severe Exacerbations NCT07629869NA1 site📍 Tel Aviv Tel-Aviv Sourasky Medical Center · Tests: Follow-up in a flare-up clinic Evaluate the Effect of Dietary Supplement Combined Exercise Among Patients With Sarcopenia Comorbid With Lung Disease NCT05926713NA1 site📍 Taichung Orient Europharma Co., Ltd. · Tests: Sarcojoint®, supervised exercise A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease NCT06300320Phase 212 sites📍 Hefei📍 Lanzhou📍 Guangzhou Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Tests: TQ05105 tablets A Clinical Study of Inhaled Nitric Oxide in Patients With Chronic Obstructive Pulmonary Disease NCT07382258NA1 site📍 Nanjing Novlead Inc. · Tests: Nitric Oxide Generation and Delivery System A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease NCT07363694Phase 2, Phase 3189 sites📍 Birmingham📍 Dothan📍 Mobile Pfizer · Tests: PF-07275315 dose 1, PF-07275315-dose 2, Placebo, PF-07275315-dose 3
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy