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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Chronic Rhinosinusitis

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy NCT06996951Phase 31 site📍 Indianapolis Indiana University · Tests: STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID, CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID Real Life Study of Biologicals in Patients With Severe CRSwNP NCT05938972n/a1 site📍 Ghent University Hospital, Ghent · Tests: Mepolizumab Efficacy and Safety of Fully Resorbable Sinus Drug-eluting Stents in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps After Surgery: A Prospective, Randomized Controlled Trial NCT07498374NA1 site📍 Xi'an Tang-Du Hospital · Tests: the fully degradable sinus stent, intranasal corticosteroids, oral corticosteroids Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis NCT05935683n/a1 site📍 Rozzano Italian Academy of Rhinology · Tests: Severe Uncontrolled Chronic Rhinosinusitis patients (CRS) Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps NCT06129552n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation A Study to Evaluate the Efficacy and Safety of HTMC0658 Tablets in the Treatment of Chronic Rhinosinusitis Without Nasal Polyps NCT07174115Phase 21 site📍 Luoyang Shanghai Yidian Pharmaceutical Technology Development Co., … · Tests: HTMC0658 Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps NCT06850805Phase 324 sites📍 Huntsville📍 Gilbert📍 Los Angeles Optinose US Inc. · Tests: OPN-375, Placebo Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR) NCT07633158n/a19 sites📍 Berlin📍 Bochum📍 Braunschweig AstraZeneca Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma NCT05708300n/a2 sites📍 Thessaloniki📍 Thessaloniki Aristotle University Of Thessaloniki · Tests: Mepolizumab 100 MG [Nucala] A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782970Phase 33 sites📍 Los Angeles📍 Tulsa📍 San Juan GlaxoSmithKline · Tests: GSK5784283, Placebo, Standard of Care CRS Questionnaire Validation Project NCT06970977n/a32 sites📍 Santa Monica📍 Chicago📍 Boston The European Forum for Research and Education in Allergy an… Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study). NCT07134686NA1 site📍 Marseille Assistance Publique Hopitaux De Marseille · Tests: Joint consultation, Mucus sampling, Nasal brushing Biologics in Chronic Rhinosinusitis With Nasal Polyposis NCT06824649Phase 43 sites📍 Gainesville📍 Portland📍 Charleston Medical University of South Carolina · Tests: Biologic Agents A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) NCT06338995Phase 3202 sites📍 Birmingham📍 Birmingham📍 Huntsville Eli Lilly and Company · Tests: LY3650150, Placebo, Standard therapy for INCS Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site📍 Chicago Northwestern University · Tests: Dupilumab - Standard Dose Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis NCT02038166n/a1 site📍 Birmingham University of Alabama at Birmingham Real-Life Chronic Rhinosinusitis Outcome Registry NCT04670172n/a13 sites📍 Graz📍 Vienna📍 Brussels Change Accelerator in Respiratory Care Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial NCT06750302Phase 1, Phase 21 site📍 Vancouver St. Paul's Hospital, Canada · Tests: Methoxyflurane - Penthrox, Placebo Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis NCT06986629NA1 site📍 Cairo Cairo University · Tests: pulsed electromagnetic therapy, Photobiostimulation, Self-sinus massage technique Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults NCT05157685Phase 313 sites📍 Bordeaux📍 Créteil📍 Le Kremlin-Bicêtre Centre Hospitalier Intercommunal Creteil · Tests: Azithromycin Oral Tablet, Placebo Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy NCT07125586NA1 site📍 Qingdao The Affiliated Hospital of Qingdao University · Tests: High-Sensitivity Spectroscopy with Autofluorescence for eCRSwNP Diagnosis The Nasal Microbiome and Its Importance in Disease NCT05061329n/a1 site📍 Holstebro University of Aarhus Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps NCT07132827Phase 31 site📍 Shanghai Guangdong Hengrui Pharmaceutical Co., Ltd · Tests: SHR-1905 Injection, SHR-1905 Placebo Injection Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). NCT07814924Phase 47 sites📍 Barakaldo📍 Jerez de la Frontera📍 Madrid Instituto de Investigación Marqués de Valdecilla · Tests: surgical arm, Mepolizumab 100 MG, combined arm Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough NCT05110144Phase 21 site📍 Rochester Mayo Clinic · Tests: Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG, Amitriptyline 50 MG, Placebo 30 MG The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS) NCT05882903Phase 24 sites📍 Sydney📍 Brisbane📍 Adelaide Oticara Australia PTY LTD · Tests: Betamethasone Dipropionate Nasal Cream 0.0644%, Pre-filled syringe and applicator device Comparative Effects of Therapeutic Ultrasound and Sinus Massage in Chronic Rhinosinusitis: a Randomized Controlled Study NCT06960876NA1 site📍 Islamabad Foundation University Islamabad · Tests: Therapeutic Ultrasound, Sinus Massage, Control group Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms NCT07262450NA32 sites📍 Bordeaux📍 Bourg-la-Reine📍 Cabourg Laboratoire de la Mer · Tests: Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Bab… Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis NCT05427695Phase 21 site📍 Chicago University of Illinois Chicago · Tests: Lactobacillus sakei proBio65, Isotonic Saline Solution Opioid-Free Anesthesia in FESS: A Prospective ERAS Study NCT07812389n/a1 site📍 Ankara Filiz Kaya · Tests: Dexmedetomidine, Remifentanil
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