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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Chronic Rhinosinusitis (Diagnosis)

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy NCT06996951Phase 31 site📍 Indianapolis Indiana University · Tests: STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID, CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis NCT05935683n/a1 site📍 Rozzano Italian Academy of Rhinology · Tests: Severe Uncontrolled Chronic Rhinosinusitis patients (CRS) Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps NCT06129552n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma NCT05708300n/a2 sites📍 Thessaloniki📍 Thessaloniki Aristotle University Of Thessaloniki · Tests: Mepolizumab 100 MG [Nucala] A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782970Phase 33 sites📍 Los Angeles📍 Tulsa📍 San Juan GlaxoSmithKline · Tests: GSK5784283, Placebo, Standard of Care Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study). NCT07134686NA1 site📍 Marseille Assistance Publique Hopitaux De Marseille · Tests: Joint consultation, Mucus sampling, Nasal brushing Biologics in Chronic Rhinosinusitis With Nasal Polyposis NCT06824649Phase 43 sites📍 Gainesville📍 Portland📍 Charleston Medical University of South Carolina · Tests: Biologic Agents Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site📍 Chicago Northwestern University · Tests: Dupilumab - Standard Dose Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis NCT02038166n/a1 site📍 Birmingham University of Alabama at Birmingham Real-Life Chronic Rhinosinusitis Outcome Registry NCT04670172n/a13 sites📍 Graz📍 Vienna📍 Brussels Change Accelerator in Respiratory Care Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis NCT06986629NA1 site📍 Cairo Cairo University · Tests: pulsed electromagnetic therapy, Photobiostimulation, Self-sinus massage technique Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults NCT05157685Phase 313 sites📍 Bordeaux📍 Créteil📍 Le Kremlin-Bicêtre Centre Hospitalier Intercommunal Creteil · Tests: Azithromycin Oral Tablet, Placebo Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy NCT07125586NA1 site📍 Qingdao The Affiliated Hospital of Qingdao University · Tests: High-Sensitivity Spectroscopy with Autofluorescence for eCRSwNP Diagnosis The Nasal Microbiome and Its Importance in Disease NCT05061329n/a1 site📍 Holstebro University of Aarhus Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough NCT05110144Phase 21 site📍 Rochester Mayo Clinic · Tests: Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG, Amitriptyline 50 MG, Placebo 30 MG The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS) NCT05882903Phase 24 sites📍 Sydney📍 Brisbane📍 Adelaide Oticara Australia PTY LTD · Tests: Betamethasone Dipropionate Nasal Cream 0.0644%, Pre-filled syringe and applicator device Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms NCT07262450NA32 sites📍 Bordeaux📍 Bourg-la-Reine📍 Cabourg Laboratoire de la Mer · Tests: Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Bab… Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis NCT05427695Phase 21 site📍 Chicago University of Illinois Chicago · Tests: Lactobacillus sakei proBio65, Isotonic Saline Solution Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label NCT07689773Phase 21 site📍 Charleston Medical University of South Carolina · Tests: Trigeminal Nerve Stimulation-enhanced Smell Training Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP NCT05094570Phase 41 site📍 Charlottesville University of Virginia · Tests: Dupilumab Prefilled Syringe Establishing Personalized Phage Therapy and Its Comparative Cost in Difficult-to-treat Infections (EPHICACI) NCT06368388n/a1 site📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Prospective data collection phage therapy, Prospective data collection standard-of-care Complete Remission After Treatment With Biologics for Nasal Polyps NCT07268313Phase 46 sites📍 Copenhagen📍 Hillerød📍 Køge Copenhagen University Hospital, Rigshospitalet · Tests: DUPIXENT®, NUCALA®, Dupi discontinuation, Mepo discontinuation In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps NCT02975310NA4 sites📍 Vancouver📍 London📍 Ottawa Ottawa Hospital Research Institute · Tests: Endoscopic polypectomy in clinic (EPIC), Endoscopic Sinus Surgery (ESS), General Anesthesia, Local and topical anesthes… Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps NCT07860411n/a1 site📍 Sanliurfa Harran University · Tests: Nasal polyp tissue and blood sampling, Nasal mucosa and blood sampling Sinus Disease in Young Children With Cystic Fibrosis NCT06191640n/a6 sites📍 Aurora📍 Iowa City📍 Kansas City University of California, Los Angeles · Tests: Ivacaftor or elexacaftor/tezacaftor/ivacaftor Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis. NCT04645511NA1 site📍 Tampere Tampere University Hospital · Tests: Balloon sinuplasty of maxillary sinuses, Sham surgery Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training NCT07681973NA1 site📍 Cleveland The Cleveland Clinic · Tests: Smell Training ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia NCT07399665n/a10 sites📍 Kazan'📍 Kemerovo📍 Krasnoyarsk AstraZeneca BIOlogics in Severe Nasal POlyposis SurvEy.: a French Registry NCT06501807NA2 sites📍 Lille📍 Lille University Hospital, Lille · Tests: Biologic treatments available in Chronic Rhinosinusitis with Nasal Polyps (dupilumab, mepolizumab and benralizumab acco… Triamcinolone Nanocapsules After Endoscopic Nasal Surgery NCT07714525Phase 21 site📍 Minya Deraya University · Tests: Triamcinolone Acetonide-Loaded Polymeric Nanocapsules, Normal Saline Nasal Irrigation
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