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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Cutaneous Melanoma, Stage II

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma NCT03860883NA192 sites📍 Mobile📍 Gilbert📍 Phoenix Melanoma and Skin Cancer Trials Limited · Tests: Wide Local Excision = 1cm Margin, Wide Local Excision = 2cm Margin Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLC NCT07718243Phase 1, Phase 22 sites📍 Manchester📍 Sutton Institute of Cancer Research, United Kingdom · Tests: Bexmarilimab 1mg/kg and nivolumab 1mg/kg, Bexmarilimab 3mg/kg and nivolumab 1mg/kg, Recommended Phase II Dose Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma NCT04598009Phase 22 sites📍 La Jolla📍 San Francisco University of California, San Francisco · Tests: Binimetinib, Imatinib Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma NCT04697576Phase 11 site📍 Columbus Carlo Contreras · Tests: Ipilimumab, Nivolumab, Pembrolizumab, Quadrivalent Inactivated Influenza Vaccine, Resection Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial NCT07155317Phase 22 sites📍 Atlanta📍 Atlanta Emory University · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Ipilimumab, Magnetic Resonance Imaging A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors NCT07070232Phase 1, Phase 277 sites📍 Phoenix📍 San Francisco📍 Hartford BioNTech SE · Tests: BNT326, Pumitamig, Itraconazole, Paroxetine Axelopran and Nivolumab in PD-1-Refractory Metastatic Melanoma NCT07631325Phase 1, Phase 21 site📍 Pittsburgh John Kirkwood · Tests: Axelopran, Nivolumab Neoadjuvant Tebentafusp for Uveal Melanoma NCT06414590Phase 22 sites📍 Philadelphia📍 Philadelphia Thomas Jefferson University · Tests: Tebentafusp-Tebn Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective Trial NCT07847359Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Cryoablation, Iparomlimab and Tuvonralimab, Dacarbazine, Lenvatinib A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information NCT07621614Phase 213 sites📍 Oakland📍 Wilmington📍 Jacksonville Children's Oncology Group · Tests: Biospecimen Collection, Chest Radiography, Computed Tomography, Fludeoxyglucose F-18, Magnetic Resonance Imaging Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain NCT05588453Phase 1, Phase 21 site📍 Columbus Kari Kendra · Tests: Natural Killer Cell Therapy, Temozolomide Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) NCT03340129Phase 29 sites📍 Sydney📍 Waratah📍 Wollstonecraft Melanoma Institute Australia · Tests: Ipilimumab, Nivolumab, Stereotactic Radiotherapy, Salvage therapy Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma NCT05527795n/a1 site📍 Pierre-Bénite Hospices Civils de Lyon · Tests: Frequency and duration of response to adjuvant immunotherapy according to clinical features, Frequency of each type of … Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma NCT06240143Phase 1, Phase 26 sites📍 Amsterdam📍 Amsterdam📍 Groningen The Netherlands Cancer Institute · Tests: Ipilimumab, Nivolumab, Nivolumab Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma NCT05428007Phase 24 sites📍 Los Angeles📍 Boston📍 Boston NYU Langone Health · Tests: Sarilumab, Ipilimumab Injection, Nivolumab/Relatlimab Assessment of Short Immunotherapy After Radical Surgery of High-risk Malignant Melanoma NCT06488482Phase 326 sites📍 Helsinki📍 Kuopio📍 Tampere Uppsala University · Tests: nivolumab or pembrolizumab Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation) NCT06999980Phase 21 site📍 Wollstonecraft Melanoma Institute Australia · Tests: Ipilimumab 3mg/kg and nivolumab 1mg/kg, Ipilimumab 1mg/kg Nivolumab 480mg and relatlimab 160mg, Nivolumab 480mg and rel… Neoadjuvant SHR-1210 Plus Apatinib for Resectable Stage III-IV Acral Melanoma NCT04331093Phase 21 site📍 Changchun Di Wu · Tests: SHR-1210+Apatinib Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases NCT05026983Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Binimetinib, Encorafenib, Questionnaire Administration Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study NCT07215988n/a1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Non-Interventional Study Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary NCT02828202n/a27 sites📍 Amiens📍 Annecy📍 Besançon Assistance Publique - Hôpitaux de Paris · Tests: Biological, Tissular, Quality of life NeoLIPA: Neoadjuvant LTX-315 in Combination with Pembrolizumab in Resectable Stage III/IV Melanoma NCT06651151Phase 21 site📍 Oslo Oslo University Hospital · Tests: LTX-315 + pembrolizumab Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma. NCT07206017NA1 site📍 Groningen University Medical Center Groningen · Tests: prebiotic dried chicory root (WholeFiber) A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients NCT01638676Phase 1, Phase 21 site📍 Louisville University of Louisville · Tests: Vemurafenib, Metformin Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a Prior History of Melanoma NCT07040280Phase 21 site📍 Pittsburgh ECOG-ACRIN Cancer Research Group · Tests: Biopsy Procedure, Biospecimen Collection, Placebo Administration, Sulforaphane Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer NCT03819296Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Best Practice, Biospecimen Collection, Endoscopic Procedure, Fecal Microbiota Transplantation, Infliximab Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial NCT06965231Phase 24 sites📍 Shanghai📍 Shanghai📍 Shanghai Fudan University · Tests: Toripalimab combined with Endostar Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site📍 Jerusalem Hadassah Medical Organization · Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin
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