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30 recruiting trials

for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma NCT06606028n/a1 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Blood Specimen Collection, Tumor Tissue Collection, Medical Record Review A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan Towards Cure Via Only Ultra-short ICB in CSCC NCT06823479Phase 25 sites๐Ÿ“ Maastricht๐Ÿ“ Amsterdam๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: Nivolumab, Ipilumimab A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430Phase 1, Phase 213 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ New Haven GV20 Therapeutics ยท Tests: GV20-0251, GV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDAยฎ], GV20-0251 and Pembrolizumab [KEYTRUDAยฎ] Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab (89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma NCT05747625Phase 11 site๐Ÿ“ Nashville Eben Rosenthal ยท Tests: Panitumumab, Zirconium Zr 89 Panitumumab, Positron Emission Tomography, Computed Tomography, Electronic Health Record Rโ€ฆ Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors NCT04119024Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Stanford Anusha Kalbasi ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Phosphate Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site๐Ÿ“ Atlanta Emory University ยท Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib A Study of IDP-001 in Advanced or Metastatic Solid Tumors NCT07602842Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ Indianapolis InduPro, Inc. ยท Tests: IDP-001 Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment NCT06589804Phase 3202 sites๐Ÿ“ Little Rock๐Ÿ“ Marysville๐Ÿ“ Palo Alto National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab Cemiplimab and Quad Shot Radiation for Cutaneous Squamous Cell Carcinoma in the Head and Neck NCT07869823EARLY Phase 11 site๐Ÿ“ St Louis Vanderbilt-Ingram Cancer Center ยท Tests: Cemiplimab, Radiation Therapy A Study of VET3-TGI in Patients With Solid Tumors NCT06444815Phase 17 sites๐Ÿ“ Los Angeles๐Ÿ“ Orange๐Ÿ“ Miami KaliVir Immunotherapeutics ยท Tests: VET3-TGI, Atezolizumab A Study of Sigvotatug Vedotin in Advanced Solid Tumors NCT04389632Phase 1158 sites๐Ÿ“ Anchorage๐Ÿ“ Fayetteville๐Ÿ“ Rogers Seagen, a wholly owned subsidiary of Pfizer ยท Tests: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatin A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers NCT05910827Phase 1, Phase 220 sites๐Ÿ“ Sydney๐Ÿ“ Westmead๐Ÿ“ Brisbane Hummingbird Bioscience ยท Tests: HMBD-001, Docetaxel, Cetuximab Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites๐Ÿ“ Gilbert๐Ÿ“ Peoria๐Ÿ“ Phoenix NRG Oncology ยท Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer NCT07094685Phase 21 site๐Ÿ“ Ann Arbor University of Michigan Rogel Cancer Center ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Ivonescimab, Magnetic Resonance Imaging A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas NCT07217171Phase 116 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco EvolveImmune United, Inc ยท Tests: EVOLVE104, EVOLVE104 At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer NCT05969860Phase 22 sites๐Ÿ“ Jacksonville๐Ÿ“ Grand Forks Mayo Clinic ยท Tests: Clinical Encounter, Home Health Encounter, Quality-of-Life Assessment, Questionnaire Administration Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia NCT04534127NA1 site๐Ÿ“ Jerusalem Alpha Tau Medical LTD. ยท Tests: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT) Thermotherapy in Addition to SOC Palliative Radiotherapy NCT06659146NA2 sites๐Ÿ“ London๐Ÿ“ London King's College London ยท Tests: Superficial hyperthermia Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy NCT04892849n/a1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School ยท Tests: Conventional Therapy acc. to prevailing clincal approved schemes Intratumoral N17350 in Advanced Solid Tumors NCT07339176Phase 1, Phase 29 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ San Diego Onchilles Pharma Inc ยท Tests: N17350 Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck NCT05108090NA1 site๐Ÿ“ Indianapolis Indiana University ยท Tests: sentinel lymph node biopsy (SLNB) Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors NCT04068155NA2 sites๐Ÿ“ Grenoble๐Ÿ“ Lyon Alpha Tau Medical LTD. ยท Tests: DaRT- Diffusing Alpha-emitters Radiation Therapy Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection Evaluation of Skin Tests in Biotherapy Allergies NCT06971848NA1 site๐Ÿ“ Angers University Hospital, Angers ยท Tests: Drug skin tests (investigating hypersensitivity to a biotherapy)
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