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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for DIPG Brain Tumor

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion NCT04655404EARLY Phase 121 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Larotrectinib, Larotrectinib surgical rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG NCT04943848Phase 13 sites📍 Orange📍 Chicago📍 Boston Ann & Robert H Lurie Children's Hospital of Chicago · Tests: rHSC-DIPGVax, Balstilimab, Zalifrelimab CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults NCT06305910Phase 11 site📍 Minneapolis OX2 Therapeutics · Tests: Treatment with CD200AR-L A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma NCT04250064Phase 21 site📍 Mumbai Tata Memorial Centre · Tests: Bevacizumab Injection, Ultra-low-dose RT Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion NCT06333899EARLY Phase 118 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Lorlatinib, Lorlatinib with chemotherapy1, Lorlatinib with chemotherapy 2, Lorlatinib post Radiation C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) NCT04099797Phase 11 site📍 Houston Baylor College of Medicine · Tests: C7R-GD2.CART cells (IV and ICV infusion), C7R-GD2.CART cells (IV and ICV infusion) Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation NCT07076498Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: M032 ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas NCT06838676Phase 220 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: ACT001 Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age NCT05956821Phase 1, Phase 21 site📍 Miami University of Miami · Tests: SIACI of cetuximab and bevacizumab Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG NCT06221553Phase 11 site📍 Bangkok Chulalongkorn University · Tests: B7H3 specific CAR T cell with IL-7Ra signaling domain Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma NCT01106794n/a1 site📍 Washington D.C. Children's National Research Institute International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository NCT03101813n/a1 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Ribociclib, Everolimus, Temozolomide (TMZ) Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas NCT06465199Phase 1, Phase 214 sites📍 Birmingham📍 Little Rock📍 Hartford Milton S. Hershey Medical Center · Tests: Eflornithine (DFMO), AMXT 1501 Dicaprate Atovaquone Combined With Radiation in Children With Malignant Brain Tumors NCT06624371Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Atovaquone, Radiation Therapy Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). NCT07680439Phase 26 sites📍 Los Angeles📍 Atlanta📍 Chicago BrainChild Bio, Inc · Tests: BCB-276 GD2-CAR T Cells for Pediatric Brain Tumours NCT05298995Phase 11 site📍 Roma Bambino Gesù Hospital and Research Institute · Tests: GD2-CART01 (iC9-GD2-CAR T-cells) A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma NCT07589257Phase 21 site📍 Guangzhou Guangzhou Virotech Pharmaceutical Co., Ltd. · Tests: VRT106 for injection Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma NCT05717712Phase 11 site📍 Beijing Capital Medical University · Tests: Ad-TD-nsIL12 Combination Therapy for the Treatment of Diffuse Midline Gliomas NCT05009992Phase 232 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: ONC201, Radiation Therapy, Paxalisib, DNX-2401 NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 NCT05476939Phase 356 sites📍 Brussels📍 Leuven📍 Aarhus Gustave Roussy, Cancer Campus, Grand Paris · Tests: Everolimus, ONC201, Radiotherapy Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma NCT05717699Phase 11 site📍 Beijing Capital Medical University · Tests: Ad-TD-nsIL12 Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT) NCT07796061Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: TAA-T Cell, BBB Disruption Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma NCT05096481Phase 213 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors NCT05278208Phase 1, Phase 24 sites📍 Aurora📍 Cincinnati📍 Columbus Nationwide Children's Hospital · Tests: LUTATHERA® (Lutetium Lu 177 dotatate) CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma NCT04870944Phase 1, Phase 235 sites📍 Birmingham📍 Phoenix📍 Los Angeles Children's Oncology Group · Tests: Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy, Echocardiography Test, FACT Complex-targeting Curaxin… xPedite: A Study to Expedite DIPG and DMG Research NCT06140719n/a1 site📍 Los Altos xCures Targeted Pediatric High-Grade Glioma Therapy NCT05839379n/a22 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital
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