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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for ER-positive Breast Cancer

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment. NCT07062965Phase 3433 sites📍 Anchorage📍 Chandler📍 Gilbert Pfizer · Tests: PF-07248144, Fulvestrant, Everolimus, Exemestane Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NCT07214532NA49 sites📍 Phoenix📍 Scottsdale📍 Tucson Natera, Inc. · Tests: ctDNA-Guided Treatment Strategy Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) NCT06757634Phase 3239 sites📍 Jonesboro📍 Little Rock📍 Duarte Celcuity Inc · Tests: Arm A: Gedatolisib + Palbociclib + Fulvestrant, Arm B: Ribociclib + Fulvestrant, Arm C: Gedatolisib + Palbociclib + Let… Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors NCT06028022Phase 223 sites📍 Albert Lea📍 Baxter📍 Bemidji Mayo Clinic · Tests: Mushroom Extract, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Use of Imatinib to Convert Triple Negative Breast Cancer Into ER-positive Breast Cancer (I-CONIC) NCT05722795NA1 site📍 Gothenburg Vastra Gotaland Region · Tests: Imatinib 400 MG Oral Tablet Chemotherapy Omission in ER+/HER2- Breast Cancer With 1-3 Positive Lymph Nodes Receiving Extended Adjuvant Abemaciclib NCT06341621Phase 31 site📍 Shanghai Fudan University · Tests: 3-year abemaciclib without chemo, treatment of physician's choice PRE-ISPY Phase I/II Oncology Platform Program NCT05868226Phase 1, Phase 210 sites📍 Birmingham📍 Phoenix📍 Aurora QuantumLeap Healthcare Collaborative · Tests: ALX148, Fam-Trastuzumab Deruxtecan-Nxki, Zanidatamab, Tucatinib, TTX-MC138 A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer NCT06099769Phase 212 sites📍 Birmingham📍 San Francisco📍 Chicago Memorial Sloan Kettering Cancer Center · Tests: Enzalutamide, Mifepristone, TPC Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC NCT06500208Phase 21 site📍 Shanghai Shanghai Jiao Tong University School of Medicine · Tests: Adebrelimab combined with nab-paclitaxel, epirubicin and cyclophosphamide Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) NCT05512364Phase 3113 sites📍 Anderlecht📍 Brussels📍 Brussels European Organisation for Research and Treatment of Cancer … · Tests: Elacestrant, Tamoxifen, Letrozole 2.5mg, Anastrozole 1mg, Exemestane 25 MG The MASTER Study (MAmmary Cancer STatin ER Positive Study) NCT04601116Phase 31 site📍 Aarhus Aarhus University Hospital · Tests: Atorvastatin 80 Mg Oral Tablet, Placebo oral tablet Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies NCT07340541Phase 26 sites📍 New Haven📍 Baltimore📍 Rochester UNC Lineberger Comprehensive Cancer Center · Tests: SERD* + abemaciclib, SERD* + everolimus, SERD* + everolimus or capecitabine, SOC, Antiandrogen Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery NCT06450873Phase 21 site📍 Scottsdale Mayo Clinic · Tests: Coriolus Versicolor Extract, Questionnaire Administration Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer NCT07427394Phase 26 sites📍 St Louis📍 East Providence📍 Nashville AstraZeneca · Tests: Camizestrant, Atirmociclib Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer NCT05386108Phase 1, Phase 286 sites📍 Fullerton📍 Los Angeles📍 Urbana Stemline Therapeutics, Inc. · Tests: Elacestrant, Abemaciclib Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers NCT05846789Phase 27 sites📍 Atlanta📍 Carmel📍 Indianapolis Kathy Miller · Tests: SOC Chemotherapy, Tocilizumab/Tocilizumab Biosimilar A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer NCT07524855Phase 16 sites📍 New Haven📍 Sarasota📍 Boston Janssen Research & Development, LLC · Tests: JNJ-101684362 (HLD-0117) Supporting Health Including Endocrine Treatment for Long Duration NCT07482384NA1 site📍 Boston Dana-Farber Cancer Institute · Tests: SHIELD portal Local Therapy for ER/PR-positive Oligometastatic Breast Cancer NCT04698252Phase 21 site📍 São Paulo Instituto do Cancer do Estado de São Paulo · Tests: Radiotherapy, Surgery, Radiofrequency ablation Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy NCT02945579NA8 sites📍 Gilbert📍 Jacksonville📍 Honolulu M.D. Anderson Cancer Center · Tests: Undergo EBRT, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration, Partial Breast I… Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial NCT06184750Phase 211 sites📍 Tucson📍 Chicago📍 Chicago National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Mammography, Questionnaire Administration, Tamoxifen TCb vs EC-T in High Risk ER+/HER2- Breast Cancer NCT05901428Phase 31 site📍 Shanghai Fudan University · Tests: Docetaxel, Carboplatin, Epirubicin, Cyclophosphamide Omission of Adjuvant Radiotherapy in Low- and Intermediate-Risk Ductal Carcinoma In Situ After Breast-Conserving Surgery NCT07762885Phase 31 site📍 Shanghai Fudan University · Tests: Adjuvant Radiotherapy, tamoxifen Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer NCT06525766Phase 21 site📍 Scottsdale Mayo Clinic · Tests: Biospecimen Collection, Bone Scan, Capecitabine, Computed Tomography, Magnetic Resonance Imaging S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer NCT03723928NA723 sites📍 Anchorage📍 Anchorage📍 Anchorage SWOG Cancer Research Network · Tests: Usual care disease monitoring, Serum Tumor Marker directed disease monitoring, Quality-of-Life Assessment, Anxiety Ques… Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer NCT06062498Phase 23 sites📍 Chicago📍 Chicago📍 Chicago Northwestern University · Tests: elacestrant, palbociclib, abemaciclib, ribociclib A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence NCT06492616Phase 3567 sites📍 Daphne📍 Chandler📍 Gilbert Stemline Therapeutics, Inc. · Tests: Elacestrant, Anastrozole, Letrozole, Exemestane, Tamoxifen To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer NCT04660435n/a1 site📍 Prato Fondazione Sandro Pitigliani · Tests: Thymidine kinase activity Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer NCT05020860Phase 22 sites📍 Houston📍 Houston Baylor Breast Care Center · Tests: Paclitaxel, Carboplatin, Trastuzumab, Pertuzumab, Doxorubicin Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer NCT07085767Phase 3200 sites📍 Hot Springs📍 Beverly Hills📍 La Jolla Olema Pharmaceuticals, Inc. · Tests: Palazestrant, Letrozole-matching placebo, Ribociclib, Letrozole, Palazestrant matching-placebo
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