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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for ESCC

Efficacy and Safety of Anlotinib Combined With Bemocizumab for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma(ESCC) NCT07627347NA1 site📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: anlotinib+bevacizumab Camrelizumab in Combination With Apatinib Mesylate Plus Short-course Chemotherapy for Advanced ESCC NCT05738434Phase 21 site📍 Zhengzhou The First Affiliated Hospital of Zhengzhou University · Tests: Camrelizumab+Apatinib+Chemotherapy→Camrelizumab+Apatinib, Camrelizumab+Chemotherapy→Camrelizumab A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors NCT04686682Phase 1, Phase 21 site📍 Tianjin Jacobio Pharmaceuticals Co., Ltd. · Tests: JAB-8263, JAB-8263 A Phase II Study of Anlotinib + PD-1 Inhibitor vs. PD-1 Inhibitor Maintenance After First-Line Chemoimmunotherapy in Advanced ESCC (Esophageal Squamous Cell Carcinoma) NCT07863141Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: anlotinib + PD-1 inhibitor, PD-1 inhibitor Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCC NCT07403136Phase 21 site📍 Shanghai Fudan University · Tests: Vebrekotuzumab, PD-1 antibody Induction Chemo-Immunotherapy + Radiotherapy vs Concurrent Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma NCT07559045Phase 21 site📍 Zunyi Second Affiliated Hospital of Zunyi Medical University · Tests: Paclitaxel plus Cisplatin or Carboplatin (Induction Chemotherapy), Weekly Paclitaxel plus Cisplatin or Carboplatin (Con… Consolidation of Toripalimab and Capecitabine After Chemoradiotherapy in ESCC NCT07177794Phase 31 site📍 Guangzhou Sun Yat-sen University · Tests: toripalimab, capecitabine Hypofractionated vs. Conventional Chemoradiotherapy After Induction Chemo-immunotherapy for Unresectable Esophageal Squamous Cell Carcinoma NCT06912074Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Induction chemoimmunotherapy, Hypofractionated Radiation Therapy, Conventional Fractionated Radiation Therapy, Concurre… Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC NCT07038629Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: S1, Iparomlimab, Radiation Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma NCT07266363n/a1 site📍 Monrovia City of Hope Medical Center · Tests: Small RNA sequencing of exo- and cf-miRNAs, RT-qPCR quantification of cf- and exo-miRNAs (SYNERGY assay), PCR-based val… A Study Evaluating the Safety and Efficacy of JS212 Combination Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma NCT07484724Phase 21 site📍 Beijing Shanghai Junshi Bioscience Co., Ltd. · Tests: JS212, JS001, 5-FU Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC NCT06510660Phase 21 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: adebrelimab Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites📍 Seoul📍 Seoul📍 Seoul Yuhan Corporation · Tests: YH32364 PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY NCT06354140Phase 21 site📍 Chongqing Daping Hospital and the Research Institute of Surgery of th… · Tests: Tegafur Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer NCT04415853Phase 31 site📍 Beijing Sunshine Lake Pharma Co., Ltd. · Tests: Lerotinib, Irinotecan/Tegafur Sacituzumab Govitecan Combined With Tislelizumab for Locally Advanced/Metastatic Esophageal Cancer NCT07811752Phase 22 sites📍 Shanghai📍 Shanghai Shanghai Chest Hospital · Tests: Sacituzumab Tirumotecan (SKB264) plus Tislelizumab Trilaciclib for the Prevention of Chemoradiotherapy-Induced Myelosuppression in Esophageal Squamous Cell Carcinoma NCT06698692n/a1 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Trilaciclib Injection [Cosela] Adebrelimab Combined With Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma NCT07595770Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: • Adebrelimab and nab-paclitaxel, carboplatin in Combination With radiotherapy A Study of DB-1310 in Advanced/Metastatic Solid Tumors NCT05785741Phase 1, Phase 224 sites📍 Sacramento📍 Santa Monica📍 Coral Gables DualityBio Inc. · Tests: DB-1310, Trastuzumab, Osimertinib, capecitabine A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site📍 Miami Aktis Oncology, Inc. · Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC NCT04973306Phase 2, Phase 31 site📍 Shanghai Shanghai Zhongshan Hospital · Tests: Neoadjuvant Chemoradiotherapy, Tislelizumab, Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended) A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) NCT06709417Phase 21 site📍 Shanghai Shanghai Chest Hospital · Tests: Sintilimab, Chemotherapy, radiotherapy KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer NCT07481058Phase 21 site📍 Beijing Beijing Konruns Pharmaceutical Co., Ltd. · Tests: KC1036, Toripalimab, Paclitaxel, Cisplatin, KC1036 An Observational Study on the Safety and Efficacy of Immunotherapy Combined With Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma NCT07080437n/a1 site📍 Chongqing Three Gorges Hospital of Chongqing University · Tests: Immunotherapy Therapy Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma NCT06675201Phase 21 site📍 Chengdu Sichuan University · Tests: neoantigen-loaded dendritic cell vaccine (NeoDC-Vac) TDLN-sparing RT Plus Immunotherapy and Chemotherapy in Locally Advanced ESCC NCT06676449Phase 31 site📍 Shanghai Fudan University · Tests: Immunotherapy, chemotherapy: Paclitaxel/Cisplatin or other guideline recommended regimens, TDLN-sparing RT A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy NCT06769113Phase 21 site📍 Jinan Shanghai Henlius Biotech · Tests: HLX43 Adebrelimab Neoadjuvant Treatment for Resectable ESCC: 2 vs 4 Cycles Study NCT06663059Phase 21 site📍 Xi'an Tang-Du Hospital · Tests: Adebrelimab combined with albumin-bound paclitaxel and cisplatin 2 cycle, Adebrelimab combined with albumin-bound pacli… Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma NCT06122493Phase 21 site📍 Shanghai Ruijin Hospital · Tests: Tirelizumab, Nab paclitaxel, Carboplatin, Radiotherapy 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors NCT07189871Phase 1, Phase 25 sites📍 Dothan📍 Grand Rapids📍 Omaha Radiopharm Theranostics, Ltd · Tests: 177Lu-BetaBart, BetaBart + unlabeled BetaBart
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