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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Early Breast Cancer

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs) NCT07743190Phase 22 sites📍 Syracuse📍 Charleston Medical University of South Carolina · Tests: Carboplatin, Paclitaxcel, Pembrolizumab Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health The Application of "HUAXI Hole 1" in Reverse-sequence Endoscopic Nipple-sparing Mastectomy With Direct-to-implant Breast Reconstruction NCT06995118NA20 sites📍 Fuzhou📍 Guangzhou📍 Anyang Du Zhenggui · Tests: HUAXI hole 1 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC NCT06245889Phase 22 sites📍 Baltimore📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Paclitaxel, Carboplatin, Pembrolizumab, Doxorubicin, Cyclophosphamide Pucotenlimab and Anlotinib in Combination With Chemotherapy NCT07896668Phase 21 site📍 Hangzhou Zhejiang Cancer Hospital · Tests: LP Pyrotinib Plus Trastuzumab and Chemotherapy for HER2-Positive Early Breast Cancer NCT07635342Phase 21 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: Pyrotinib Maleate, Trastuzumab (H, 8mg/kg, pegylated liposomal doxorubicin hydrochloride, Cyclophosphamide, Paclitaxel … Real-world Evaluation of Patient Outcomes and Experiences With Ribociclib Early Adopters. NCT07243002n/a1 site📍 London Novartis Pharmaceuticals Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer NCT01766297Phase 29 sites📍 Scottsdale📍 San Diego📍 Warrenville Proton Collaborative Group · Tests: Proton Radiotherapy I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites📍 Birmingham📍 Scottsdale📍 Tucson QuantumLeap Healthcare Collaborative · Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Tras… Evaluation of the Effect of Regular Physical Exercise in Breast Cancer. NCT07893327NA1 site📍 San Sebastián de los Reyes Fundación Investigación E Innovación Biomédica Hospital Uni… · Tests: Supervised exercise program A Study to Determine the Efficacy of a Digital Self-management Support Tool to Improve the Quality of Life During Adjuvant HOrmonal Therapy for Patients With Early Breast Cancer NCT06781996Phase 31 site📍 Villejuif Gustave Roussy, Cancer Campus, Grand Paris · Tests: multimodal Resilience© digital companion, Standard supportive care Optimization of Cardiac Imaging in Women With Early-Stage Breast Cancer NCT07630402NA1 site📍 Rochester University of Rochester · Tests: Echocardiogram Timing of Specific Exercise Therapy After Breast Cancer Surgery: Early Versus Delayed Initiation NCT06918184NA1 site📍 Cairo Al Hayah University In Cairo · Tests: Specific Exercise Therapy The DBCG Proton Trial: Photon Versus Proton Radiation Therapy for Early Breast Cancer NCT04291378NA8 sites📍 Aalborg📍 Aarhus📍 Copenhagen Danish Breast Cancer Cooperative Group · Tests: Proton versus photon radiation therapy The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC). NCT06217185Phase 41 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: Pyrotinib, Trastuzumab, Taxanes, Capecitabine Study to Evaluate the Impact of the Use of Alternative and Complementary Therapies on Therapeutic Adherence in Patients Treated With taMoxifen for Early Stage Breast Cancer NCT04740697NA1 site📍 Toulouse Institut Claudius Regaud · Tests: Treatment requiring adjuvant Hormonal Therapy (HT) with tamoxifen. Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NCT07214532NA49 sites📍 Phoenix📍 Scottsdale📍 Tucson Natera, Inc. · Tests: ctDNA-Guided Treatment Strategy Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy NCT07386444NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Inspiratory muscle training Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer NCT06606730Phase 32 sites📍 Brussels📍 Villejuif UNICANCER · Tests: Pembrolizumab, Deescalation Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies NCT07211178n/a16 sites📍 Birmingham📍 Whittier📍 Weston Tempus AI · Tests: There are no interventions in this observational study. Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer NCT07373782Phase 2, Phase 31 site📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Continuous Positive Airway Pressure (CPAP) NeoAdj. Therapy Comparing Sacituzumab Govitecan (SG) vs. SG+Pembrolizumab in Low-risk, Triple-neg. EBC (ADAPT-TN-III) NCT06081244Phase 343 sites📍 Baden-Baden📍 Böblingen📍 Freiburg im Breisgau Women's Cancer Study Group GmbH · Tests: Sacituzumab govitecan, Pembrolizumab A Prospective, Multicenter Registry to Observe the Treatment Patterns, Clinical Outcomes, and Decision-Making in Patients With Early Breast Cancer Eligible for EndoPredict® Testing NCT07389408n/a13 sites📍 Athens📍 Athens📍 Athens National and Kapodistrian University of Athens Phase II Trial of Anti-HER2 Treatment in HER2-enriched Early Breast Cancer Identified by PAM50 (HER2E-PAM, PAMILIA Study) NCT04817540Phase 21 site📍 Seoul Gangnam Severance Hospital · Tests: Herzuma JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year NCT06930521NA1 site📍 Toronto Women's College Hospital · Tests: Intervention - Low Risk Group OR Intermediate Risk Group "The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients" NCT06679387Phase 21 site📍 Cairo Ain Shams University · Tests: Memantine-HCl, Placebo Oral Tablet Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer NCT03936478Phase 21 site📍 Madison University of Wisconsin, Madison · Tests: MRIdian Radiation Treatment Unit Study Of Capecitabine Combined With Camrelizumab For Non-pCR TNBC With TLS After Neoadjuvant Chemoterapy NCT06313463Phase 31 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: Carrellizumab + Capecitabine, Placebo + Capecitabine Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE) NCT06445738NA9 sites📍 San Francisco📍 Houston📍 Camperdown Breast Cancer Trials, Australia and New Zealand · Tests: Arm A: Radiotherapy Omission, Arm B: Standard Treatment Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy NCT05978648Phase 21 site📍 Guangzhou wang shusen · Tests: Trilaciclib, Epirubicin, Cyclophosphamide, Paclitaxel, Docetaxel
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