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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Early-stage Breast Cancer

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs) NCT07743190Phase 22 sites๐Ÿ“ Syracuse๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Carboplatin, Paclitaxcel, Pembrolizumab The Application of "HUAXI Hole 1" in Reverse-sequence Endoscopic Nipple-sparing Mastectomy With Direct-to-implant Breast Reconstruction NCT06995118NA20 sites๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou๐Ÿ“ Anyang Du Zhenggui ยท Tests: HUAXI hole 1 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC NCT06245889Phase 22 sites๐Ÿ“ Baltimore๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Paclitaxel, Carboplatin, Pembrolizumab, Doxorubicin, Cyclophosphamide Pucotenlimab and Anlotinib in Combination With Chemotherapy NCT07896668Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: LP Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer NCT01766297Phase 29 sites๐Ÿ“ Scottsdale๐Ÿ“ San Diego๐Ÿ“ Warrenville Proton Collaborative Group ยท Tests: Proton Radiotherapy I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Tucson QuantumLeap Healthcare Collaborative ยท Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Trasโ€ฆ Evaluation of the Effect of Regular Physical Exercise in Breast Cancer. NCT07893327NA1 site๐Ÿ“ San Sebastiรกn de los Reyes Fundaciรณn Investigaciรณn E Innovaciรณn Biomรฉdica Hospital Uniโ€ฆ ยท Tests: Supervised exercise program A Study to Determine the Efficacy of a Digital Self-management Support Tool to Improve the Quality of Life During Adjuvant HOrmonal Therapy for Patients With Early Breast Cancer NCT06781996Phase 31 site๐Ÿ“ Villejuif Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: multimodal Resilienceยฉ digital companion, Standard supportive care Optimization of Cardiac Imaging in Women With Early-Stage Breast Cancer NCT07630402NA1 site๐Ÿ“ Rochester University of Rochester ยท Tests: Echocardiogram The DBCG Proton Trial: Photon Versus Proton Radiation Therapy for Early Breast Cancer NCT04291378NA8 sites๐Ÿ“ Aalborg๐Ÿ“ Aarhus๐Ÿ“ Copenhagen Danish Breast Cancer Cooperative Group ยท Tests: Proton versus photon radiation therapy Study to Evaluate the Impact of the Use of Alternative and Complementary Therapies on Therapeutic Adherence in Patients Treated With taMoxifen for Early Stage Breast Cancer NCT04740697NA1 site๐Ÿ“ Toulouse Institut Claudius Regaud ยท Tests: Treatment requiring adjuvant Hormonal Therapy (HT) with tamoxifen. Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy NCT07386444NA1 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: Inspiratory muscle training Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer NCT06606730Phase 32 sites๐Ÿ“ Brussels๐Ÿ“ Villejuif UNICANCER ยท Tests: Pembrolizumab, Deescalation Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies NCT07211178n/a16 sites๐Ÿ“ Birmingham๐Ÿ“ Whittier๐Ÿ“ Weston Tempus AI ยท Tests: There are no interventions in this observational study. Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer NCT07373782Phase 2, Phase 31 site๐Ÿ“ Leuven Universitaire Ziekenhuizen KU Leuven ยท Tests: Continuous Positive Airway Pressure (CPAP) Phase II Trial of Anti-HER2 Treatment in HER2-enriched Early Breast Cancer Identified by PAM50 (HER2E-PAM, PAMILIA Study) NCT04817540Phase 21 site๐Ÿ“ Seoul Gangnam Severance Hospital ยท Tests: Herzuma JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year NCT06930521NA1 site๐Ÿ“ Toronto Women's College Hospital ยท Tests: Intervention - Low Risk Group OR Intermediate Risk Group "The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients" NCT06679387Phase 21 site๐Ÿ“ Cairo Ain Shams University ยท Tests: Memantine-HCl, Placebo Oral Tablet Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer NCT03936478Phase 21 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: MRIdian Radiation Treatment Unit Study Of Capecitabine Combined With Camrelizumab For Non-pCR TNBC With TLS After Neoadjuvant Chemoterapy NCT06313463Phase 31 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Carrellizumab + Capecitabine, Placebo + Capecitabine Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy NCT05978648Phase 21 site๐Ÿ“ Guangzhou wang shusen ยท Tests: Trilaciclib, Epirubicin, Cyclophosphamide, Paclitaxel, Docetaxel Evaluation of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT for Predicting Pathological Complete Response After Neoadjuvant Chemotherapy in HER2 Positive Early Breast Cancer NCT07593976Phase 21 site๐Ÿ“ Rouen Centre Henri Becquerel ยท Tests: [68Ga]Ga-NOTA-anti-HER2-sdAb Positron Emission Tomography Dalpicilib-Enhanced vs. Standard Endocrine Therapy in ER+ HER2- Early Breast Cancer NCT06637150Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Dalpicilib, endocrine therapy Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations NCT00823654n/a8 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Blood draw and questionnaires, Blood draw and questionnaires Effects of Physical Activity in Early Stage Hormone Receptor Positive Breast Cancer Patients NCT07539038n/a1 site๐Ÿ“ Aviano Centro di Riferimento Oncologico - Aviano A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer NCT06508216Phase 1, Phase 21 site๐Ÿ“ Villejuif Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: Dato-DXd, Durvalumab A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer NCT07054190Phase 237 sites๐Ÿ“ Los Angeles๐Ÿ“ Orange๐Ÿ“ Germantown Hoffmann-La Roche ยท Tests: Inavolisib, Ribociclib, Letrozole, Giredestrant Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC NCT06500208Phase 21 site๐Ÿ“ Shanghai Shanghai Jiao Tong University School of Medicine ยท Tests: Adebrelimab combined with nab-paclitaxel, epirubicin and cyclophosphamide Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab NCT05877859n/a1 site๐Ÿ“ Atlanta Emory University A Study to Assess Treatment Patterns and Treatment Adherence in Early HER2-positive Breast Cancer Participants After Treatment Decentralization NCT07527741n/a10 sites๐Ÿ“ Loznica๐Ÿ“ Poลพarevac๐Ÿ“ Bor Hoffmann-La Roche
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