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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Emphysema

Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD) NCT07326592Phase 42 sites๐Ÿ“ Aalborg๐Ÿ“ Vejle CSL Behring ยท Tests: CE1226 A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD) NCT07227207Phase 1, Phase 28 sites๐Ÿ“ Jacksonville๐Ÿ“ Boston๐Ÿ“ Rochester Tessera Therapeutics, Inc. ยท Tests: TSRA-196 A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD NCT06405633Phase 1, Phase 29 sites๐Ÿ“ Fitzroy๐Ÿ“ Halifax๐Ÿ“ Toronto Wave Life Sciences USA, Inc. ยท Tests: WVE-006 Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment NCT06025500n/a1 site๐Ÿ“ Groningen University Medical Center Groningen ยท Tests: 31P-Magnetic Resonance Spectroscopy (31P-MRS) Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD NCT07059637NA1 site๐Ÿ“ Cleveland The Cleveland Clinic ยท Tests: Multidisciplinary clinic evaluation, COPD standard of care Change in Task-related Oxygen Uptake After EBV Treatment NCT06702072n/a1 site๐Ÿ“ Groningen University Medical Center Groningen ยท Tests: Endobronchial valve treatment Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction NCT05257681NA1 site๐Ÿ“ Boston Beth Israel Deaconess Medical Center ยท Tests: Interlobar fissure completion and pleural adhesiolysis Unilateral vs. Bilateral Lung Volume Reduction Surgery NCT07731958NA1 site๐Ÿ“ Copenhagen Copenhagen University Hospital, Rigshospitalet ยท Tests: Unilateral LVRS, Bilateral LVRS Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction NCT07152834n/a1 site๐Ÿ“ MuฤŸla MuฤŸla Sฤฑtkฤฑ Koรงman University ยท Tests: Blood Sampling Emphysema Research Registry and Biosample Repository NCT00307281n/a1 site๐Ÿ“ Pittsburgh University of Pittsburgh Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema NCT04801108NA1 site๐Ÿ“ Boston Beth Israel Deaconess Medical Center ยท Tests: Robotic or VATS lobar fissure completion, Endobronchial valves placement Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure NCT03500731Phase 1, Phase 22 sites๐Ÿ“ Pittsburgh๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: CD3/CD19 negative hematopoietic stem cells, Rituximab, Alemtuzumab, Fludarabine, Thiotepa The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema NCT06655428NA7 sites๐Ÿ“ Vienna๐Ÿ“ Vienna๐Ÿ“ Berlin Morair Medtech, LLC ยท Tests: Endobronchial Therman Liquid Ablation (ETLA) A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) NCT07759245Phase 2127 sites๐Ÿ“ Birmingham๐Ÿ“ Newport Beach๐Ÿ“ San Diego Eli Lilly and Company ยท Tests: Brenipatide, Placebo, Standard of Care A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD) NCT07431112Phase 113 sites๐Ÿ“ Melbourne๐Ÿ“ Tbilisi๐Ÿ“ Tbilisi AIRNA Corporation ยท Tests: AIR-001 SAD dose level 1, AIR-001 SAD dose level 2, AIR-001 SAD dose level 3, AIR-001 SAD dose level 4, AIR-001 MD doseโ€ฆ A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema NCT06152107NA9 sites๐Ÿ“ Zhengzhou๐Ÿ“ Beijing๐Ÿ“ Chengdu Shanghai Chest Hospital ยท Tests: BTVA treatment plus optimal medical therapy (GOLD guidelines) A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems NCT06512454n/a8 sites๐Ÿ“ Gainesville๐Ÿ“ Charleston๐Ÿ“ Nashville Takeda ยท Tests: No Intervention The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study NCT00500123n/a1 site๐Ÿ“ Gainesville University of Florida ยท Tests: Alpha-1 Antitrypsin Genotype Surgical Compared to Bronchoscopic Lung Volume Reduction in Patients With Severe Emphysema NCT04537182NA6 sites๐Ÿ“ Vienna๐Ÿ“ Leuven๐Ÿ“ Copenhagen Isabelle Opitz, Professor, MD ยท Tests: Lung volume reduction surgery, Bronchoscopic lung volume reduction with valves Kingston Chronic Obstructive Pulmonary Disease (COPD) Multidimensional Long Term Follow up Cohort NCT04200079n/a1 site๐Ÿ“ Kingston Dr. Juan Pablo de Torres Tajes Clinical-ultrasonographic Assessment of Pulmonary Emphysema NCT06533371NA4 sites๐Ÿ“ Acquaviva delle Fonti๐Ÿ“ Naples๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: Relationship between lung ultrasound and computed tomographic scan Characterizing Matrix Metalloproteinase-12 (MMP12) in Sputum NCT04761393n/a1 site๐Ÿ“ Hamilton McMaster University ยท Tests: Hyperpolarized 129Xe (Xenon) diffusion-weighted MRI A Trial of the Implantable Artificial Bronchus 50 Flex in Patients With Severe Emphysema NCT07086339NA2 sites๐Ÿ“ Limoges๐Ÿ“ Groningen Pulmair Medical, Inc. ยท Tests: Implantable pulmonary stent Endobronchial Silicone Valve for Patients With Emphysema NCT07097896NA1 site๐Ÿ“ Beijing China-Japan Friendship Hospital ยท Tests: ESV, Optimal Medical Management (OMM) COPD Patient-Powered Research Network NCT02803242n/a1 site๐Ÿ“ Washington D.C. COPD Foundation ยท Tests: Patient Reported Outcomes Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap NCT03263130n/a2 sites๐Ÿ“ Lakewood๐Ÿ“ Lakewood Gelb, Arthur F., M.D. ยท Tests: As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) NCT06001645n/a4 sites๐Ÿ“ Cagliari๐Ÿ“ Milan๐Ÿ“ Pisa Universitร  Vita-Salute San Raffaele ยท Tests: Blood and bronchoalveolar fluid collection and analysis, Chest CT scan Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath NCT06528418n/a1 site๐Ÿ“ Guangzhou ChromX Health ยท Tests: Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (ฮผGC-PID) system Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs NCT01851642n/a1 site๐Ÿ“ Gainesville University of Florida ยท Tests: History and physical exam., Blood draw., Pulmonary function testing., Albuterol inhaler. Alpha-1 Research Registry NCT04157049n/a1 site๐Ÿ“ Coral Gables Alpha-1 Foundation
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