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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Esketamine

Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study NCT07247968EARLY Phase 12 sites📍 Chongqing📍 Chongqing Min Su · Tests: Esketamine injection group (0.25 mg/kg), Saline injection group (Consistent with esketamine injection volume) Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression NCT07146503n/a5 sites📍 Genova📍 Genova📍 Chieti Riccardo Guglielmo · Tests: Esketamine (Intranasal Spray) Metabolic Profiling of Esketamine Treatment in Depressive Disorder NCT07002684n/a1 site📍 Zagreb University of Zagreb · Tests: Esketamine Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort NCT06399185Phase 42 sites📍 Beijing📍 Shenzhen Peking University First Hospital · Tests: Normal saline, Dexmedetomidine, Esketamine, Combined dexmedetomidine-esketamine Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression NCT05450432Phase 41 site📍 Boston Massachusetts General Hospital · Tests: Ketamine, Esketamine Ayahuasca, Esketamine and Premenstrual Symptoms NCT07317232NA1 site📍 Ribeirão Preto University of Sao Paulo · Tests: Ayahuasca, Esketamine Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality NCT07002723NA1 site📍 Shenzhen Peking University Shenzhen Hospital · Tests: Esketamine combined with dexmedetomidine, Normal saline Positioning of Esketamine Treatment in the Real-world Management of Depression NCT06103760Phase 41 site📍 St Leonards Royal North Shore Hospital · Tests: Esketamine Nasal Spray [Spravato] Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery NCT06778811Phase 42 sites📍 Nanjing📍 Nanjing Nanjing First Hospital, Nanjing Medical University · Tests: Intraoperative infusion of dexmedetomidine, Intraoperative infusion of esketamine, Saline control Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression NCT07422519NA1 site📍 Barcelona Hospital Universitari Vall d'Hebron Research Institute · Tests: Virtual-Reality-based mindfulness intervention, Esketamine Treatment as Usual (ESK) At-Home tDCS as Maintenance Therapy NCT07269964NA2 sites📍 München📍 München Technical University of Munich · Tests: tDCS The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia NCT07699523NA2 sites📍 Beijing📍 Beijing China-Japan Friendship Hospital · Tests: Midazolam, Dexmedetomidine, Esketamine, Propofol, Remifentanil Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia NCT06853431Phase 42 sites📍 Wenzhou📍 Wenzhou Second Affiliated Hospital of Wenzhou Medical University · Tests: dexmedetomidine, Esketamine Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants. NCT07736352NA1 site📍 Beijing China-Japan Friendship Hospital · Tests: Propofol + Remifentanil +Midazolam, Propofol + Remifentanil + Dexmedetomidine, Propofol + Remifentanil + Esketamine, Pr… The OBSERVE Protocol NCT06725277n/a8 sites📍 Milford📍 New Haven📍 Atlanta Yale University · Tests: Spravato, IV Ketamine Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT) NCT06817239NA6 sites📍 Fuzhou📍 Guangzhou📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: Esketamine, Normal saline Esketamine With or Without Integration Therapy for Treatment-Resistant Depression NCT07369102Phase 42 sites📍 San Juan📍 San Juan University of Puerto Rico · Tests: Esketamine hydrochloride (intranasal), Integration Therapy Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes NCT06087510Phase 41 site📍 Beijing Peking University First Hospital · Tests: Esketamine Esketamine Combined Pregabalin and Duloxetine for Postherpetic Neuralgia NCT06896994NA1 site📍 Beijing Beijing Tiantan Hospital · Tests: esketamine group, control group Esketamine Versus Crisis Response Planning Versus Enhanced Treatment as Usual for Suicide Prevention: A Pragmatic Randomized Trial in a Brazilian Municipality (SAVE) NCT07120477Phase 41 site📍 Indaiatuba University of Sao Paulo · Tests: Intravenous Esketamine, Crisis Response Planning (CRP), Enhanced Treatment as Usual (eTAU) Ayahuasca, Esketamine and PTSD NCT07317206Phase 21 site📍 Ribeirão Preto University of Sao Paulo · Tests: Ayahuasca, Esketamine A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression NCT07716098Phase 322 sites📍 Redlands📍 San Diego📍 Marietta Janssen Research & Development, LLC · Tests: Esketamine 56 mg, Esketamine 84 mg, Placebo Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery NCT06859892Phase 41 site📍 Beijing Peking University First Hospital · Tests: Dexmedetomidine-esketamine combination, Placebo Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia NCT06890897NA1 site📍 Beijing Beijing Tiantan Hospital · Tests: Esketamine group, PRF group The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury NCT05095857Phase 41 site📍 Copenhagen Copenhagen University Hospital, Rigshospitalet · Tests: S-ketamine, Isotonic saline (placebo) Ayahuasca, Esketamine and Body Image Perception NCT07317219NA1 site📍 Ribeirão Preto University of Sao Paulo · Tests: Ayahuasca, Esketamine Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation NCT07050212NA1 site📍 Wuhan Maternal and Child Health Hospital of Hubei Province · Tests: remimazolam group, dexmedetomidine group, esketamine group Effect of Subanesthetic Dose of Esketamine on Sleep Quality NCT06773143NA1 site📍 Nanjing Nanjing First Hospital, Nanjing Medical University · Tests: Esketamine at low dose, Normal Saline (0.9% NaCl) A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder NCT07227454Phase 344 sites📍 Birmingham📍 Washington D.C.📍 Atlanta Janssen Research & Development, LLC · Tests: Esketamine, Midazolam, Oral Placebo, Intranasal Placebo PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study NCT06713616Phase 38 sites📍 Milford📍 New Haven📍 Atlanta Yale University · Tests: Racemic ketamine, Spravato (Esketamine)
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