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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for First in Man Study to Evaluate Initial Safety

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation NCT06908434Phase 11 site📍 Shanghai Changchun GeneScience Pharmaceutical Co., Ltd. · Tests: GenSci128 tablets Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B NCT06680232Phase 17 sites📍 Boston📍 Clichy📍 Hong Kong Precision BioSciences, Inc. · Tests: PBGENE-HBV A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors NCT04686682Phase 1, Phase 21 site📍 Tianjin Jacobio Pharmaceuticals Co., Ltd. · Tests: JAB-8263, JAB-8263 Study of AT-587 in Healthy Subjects NCT07728487Phase 11 site📍 Edegem Atea Pharmaceuticals, Inc. · Tests: AT-587, Placebo A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants NCT06576271Phase 128 sites📍 Scottsdale📍 Aurora📍 Las Vegas GlaxoSmithKline · Tests: GSK4527363, Placebo matching GSK4527363, Belimumab A Study of VV-14303 for the Treatment of Metabolic Dysfunction-associated Steatohepatitis (MASH) NCT07732400Phase 1, Phase 23 sites📍 Chandler📍 Lady Lake📍 Auckland Kriya Therapeutics, Inc. · Tests: VV-14303 Sutra Hemi-valve First-in-Human Study NCT06552689NA1 site📍 Hamilton Sutra Medical, Inc. · Tests: Sutra Hemi-valve Transcatheter Mitral Valve Replacement (TMVR) System A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases NCT07284797Phase 11 site📍 Melbourne Xencor, Inc. · Tests: XmAb657 Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001 NCT06410092Phase 13 sites📍 Beijing📍 Chongqing📍 Chengdu Sound Biopharmaceuticals Ltd. · Tests: FTL001 A Phase 1 Study of PVT401 in Healthy Subjects NCT07423000Phase 11 site📍 Melbourne Parvus Therapeutics, Inc. · Tests: PVT401, Normal Saline (0.9% NaCl) Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors NCT06666270Phase 12 sites📍 Zhengzhou📍 Shanghai Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd · Tests: SYN818 Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors NCT06384352Phase 121 sites📍 Aurora📍 Denver📍 North Haven MediLink Therapeutics (Suzhou) Co., Ltd. · Tests: YL211, YL211+Pembrolizumab, YL211 + Pembro or Pembro+ Pemetrexed + (Carboplatin or Cisplatin) A Phase 1, First-in-Human Study of CITY-RBP4 in Healthy Volunteers and STGD1 Participants NCT07836452Phase 11 site📍 Melbourne City Therapeutics · Tests: CITY-RBP4, Placebo A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04243785Phase 13 sites📍 Duarte📍 New York📍 Houston Edgewood Oncology Inc. · Tests: BTX-A51, Azacitidine CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors NCT07335497Phase 1, Phase 234 sites📍 Birmingham📍 Los Angeles📍 Denver Crescent Biopharma, Inc. · Tests: CR-001, Paclitaxel, trifluridine and tipiracil, Pemetrexed, Carboplatin A Study to Assess the Safety, Tolerability and How Single Ascending Doses of ABBV-859 Moves Through the Body of Healthy Adult Participants NCT07736638Phase 12 sites📍 Anaheim📍 Grayslake AbbVie · Tests: ABBV-859, Placebo for ABBV-859, ABBV-859, Placebo for ABBV-859 First-in-Human Investigation of JMT108 Injection in Participants With Advanced Malignant Tumors NCT06877650Phase 1, Phase 21 site📍 Shanghai Shanghai JMT-Bio Inc. · Tests: JMT108, Pembrolizumab, Ivonescimab SAD and MAD Study of AKB-9090 in Healthy Adult Participants NCT07429006Phase 11 site📍 Auckland Akebia Therapeutics · Tests: AKB-9090, Placebo Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites📍 Seoul📍 Seoul📍 Seoul Yuhan Corporation · Tests: YH32364 First-in-Human Single and Multiple Dose of HL-400 NCT06997484Phase 11 site📍 Baltimore Highlightll Pharmaceutical (USA) LLC · Tests: HL-400, Placebo The Bispecific PSMAxCD3 Antibody CC-1 in Patients with Castration Resistant Prostate Carcinoma NCT04104607Phase 12 sites📍 Tübingen📍 Heidelberg University Hospital Tuebingen · Tests: CC-1, PSMAxCD3 A Study of DXC014 in Patients With Advanced Solid Tumors. NCT07177937Phase 15 sites📍 Beijing📍 Changsha📍 Nanchang Hangzhou DAC Biotechnology Co., Ltd. · Tests: DXC014 A First-in-Human Study to Evaluate Implantable Iontophoresis Chemotherapy Delivery Device With Gemcitabine Once Weekly or Twice Weekly in Participants With Pancreatic Cancer NCT07481383Phase 12 sites📍 Ann Arbor📍 Morgantown Continuity Biosciences, LLC · Tests: ACT Implantable Iontophoresis Chemotherapy Delivery Device with Gemcitabine (ACT-IOP-003) A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma NCT06121843Phase 119 sites📍 Birmingham📍 Phoenix📍 Duarte Juno Therapeutics, Inc., a Bristol-Myers Squibb Company · Tests: BMS-986393, Alnuctamab, Mezigdomide, Iberdomide, Elranatamab A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors NCT07600476Phase 13 sites📍 Munich📍 Würzburg📍 Münster Kupando GmbH · Tests: KUP-101A A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours NCT06868199Phase 1, Phase 26 sites📍 Ryde📍 Ryde📍 Wollongong LaNova Medicines Limited · Tests: LM-168, Toripalimab GenSci139 in Patients With Advanced Solid Tumors NCT07230977Phase 11 site📍 Jinan Changchun GeneScience Pharmaceutical Co., Ltd. · Tests: GenSci139 Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC NCT04686305Phase 191 sites📍 Duarte📍 Newport Beach📍 Orange AstraZeneca · Tests: T-DXd, Durvalumab, Cisplatin, Carboplatin, Pemetrexed Single Ascending and Multiple Ascending Dose Study of LCA-0061 NCT07701954Phase 11 site📍 Mississauga Lycia Therapeutics, Inc. · Tests: LCA-0061, Placebo A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects NCT05942625Phase 11 site📍 Nanjing Hansoh BioMedical R&D Company · Tests: HS-10390 tablet, Placebo tablet
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