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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer NCT06121700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antiโ€ฆ A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab Adebrelimab Combined With Nab-paclitaxel, Oxaliplatin and Tegafur (AOS) for Perioperative Treatment of Locally Advanced Resectable GC/GEJ NCT06808971Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Adebrelimab, Nab-paclitaxel, Oxaliplatin, Tegafur Gimeracil Oteracil Potassium Capsule A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites๐Ÿ“ Clovis๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach Bristol-Myers Squibb ยท Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma NCT07023315Phase 36 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Shijiazhuang Akeso ยท Tests: Cadonilimab, SOX chemotherapy, Placebo Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer NCT07026149Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Apatinib+Camrelizumab+SOX, Preoperative Radiotherapy Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma NCT07569068Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Tislelizumab, LM-302 and S-1, Tislelizumab combined with oxaliplatin and S-1 A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma NCT04997837Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: PD-1 inhibitor, Oxaliplatin, Capecitabine, Tegafur-gimeracil-oteracil potassium, 5-FU Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma NCT06841679Phase 2, Phase 310 sites๐Ÿ“ Hialeah๐Ÿ“ Anyang๐Ÿ“ Guangzhou Beijing Biostar Pharmaceuticals Co., Ltd. ยท Tests: Utidelone Capsule, Utidelone Capsule, Utidelone Capsule, Fluoropyrimidine- and Platinum-containing Therapy, Oxaliplatin Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06925243Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant apatinib combined with sintilimab and perioperative SOX, Neoadjuvant sintilimab combined with perioperativeโ€ฆ A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma NCT05894824Phase 1, Phase 21 site๐Ÿ“ Seoul Yonsei University ยท Tests: T-Dxd(Trastuzmab deruxtecan), Ramucirumab HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) NCT04447352Phase 315 sites๐Ÿ“ Aachen๐Ÿ“ Dresden๐Ÿ“ Frankfurt Krankenhaus Nordwest ยท Tests: 5-Fluorouracil, Leucovorin, Oxaliplatin, Docetaxel, Cisplatin Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma NCT07699939Phase 218 sites๐Ÿ“ Chiba๐Ÿ“ Fukuoka๐Ÿ“ Gifu National Cancer Center, Japan ยท Tests: serplulimab, Placebo A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06949033Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant cadonilimab combined with perioperative SOX, Neoadjuvant placebo plus perioperative SOX A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites๐Ÿ“ Orange๐Ÿ“ Santa Monica๐Ÿ“ Chicago Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil A Study of Sigvotatug Vedotin in Advanced Solid Tumors NCT04389632Phase 1158 sites๐Ÿ“ Anchorage๐Ÿ“ Fayetteville๐Ÿ“ Rogers Seagen, a wholly owned subsidiary of Pfizer ยท Tests: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatin A Study of PD-1 Inhibitors Combined With Fruquintinib and Chemotherapy in First-line Treatment of HER2-negative Advanced G/GEJ Cancer NCT06158919NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Fruquintinibใ€Nivolumabใ€Sintilimabใ€Oxaliplatinใ€Teysunoใ€Capecitabine Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 NCT07431281Phase 3314 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Anchorage AstraZeneca ยท Tests: Sonesitatug vedotin, Rilvegostomig, Nivolumab, Capecitabine, 5-Fluorouracil A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer NCT07673887Phase 38 sites๐Ÿ“ Saint Louis Park๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Capecitabine, Folinic acid Adebrelimab With Chemoradiotherapy and Surgery for G/GEJ NCT06985602Phase 21 site๐Ÿ“ Nanjing Jiangsu Cancer Institute & Hospital ยท Tests: Arm 1: Adebrelimab Combined with Chemoradiotherapy Followed by Surgery A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer NCT07631000Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Cadonilimab Phase II Trial of Iparomlimab/Tuvonralimab (QL1706) + XELOX in HER2-Negative, Low PD-L1 G/GEJ Adenocarcinoma NCT06932068Phase 229 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dezhou Qilu Hospital of Shandong University ยท Tests: Iparomlimab and Tuvonralimab (QL1706), Oxallplation, Capectitabine Tablets M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. NCT06177041Phase 31 site๐Ÿ“ Beijing FutureGen Biopharmaceutical (Beijing) Co., Ltd ยท Tests: M108 monoclonal antibody, Placebo, Oxaliplatin, Capecitabine First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors NCT07284186Phase 110 sites๐Ÿ“ Scottsdale๐Ÿ“ Duarte๐Ÿ“ Orange Plexium, Inc. ยท Tests: PLX-61639 Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT05702229Phase 244 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Baton Rouge AstraZeneca ยท Tests: Rilvegostomig, Volrustomig, FOLFOX, XELOX, AZD0901 BC001 in Combination with Sintilimab and XELOX in the Treatment of HER-2 Negative Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma. NCT06773312Phase 11 site๐Ÿ“ Beijing Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. ยท Tests: BC001+Sintilimab+XELOX
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