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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Gastroesophageal Junction (GEJ) Adenocarcinoma

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer NCT06121700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antiโ€ฆ AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer NCT06196697Phase 21 site๐Ÿ“ Harbin Harbin Medical University ยท Tests: Cadonilimab, Ivonescimab, XELOX, SOX A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Duarte Seagen, a wholly owned subsidiary of Pfizer ยท Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) Adebrelimab Combined With Nab-paclitaxel, Oxaliplatin and Tegafur (AOS) for Perioperative Treatment of Locally Advanced Resectable GC/GEJ NCT06808971Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Adebrelimab, Nab-paclitaxel, Oxaliplatin, Tegafur Gimeracil Oteracil Potassium Capsule A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites๐Ÿ“ Clovis๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach Bristol-Myers Squibb ยท Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma NCT07023315Phase 36 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Shijiazhuang Akeso ยท Tests: Cadonilimab, SOX chemotherapy, Placebo Dual-target CLDN18.2/HER2 CAR-NK Cells for Advanced Gastric/GEJ Cancer NCT07551362Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DT-CAR-NK, Fludarabine, Cyclophosphamide Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer NCT07026149Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Apatinib+Camrelizumab+SOX, Preoperative Radiotherapy Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma NCT07569068Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Tislelizumab, LM-302 and S-1, Tislelizumab combined with oxaliplatin and S-1 A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma NCT04997837Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: PD-1 inhibitor, Oxaliplatin, Capecitabine, Tegafur-gimeracil-oteracil potassium, 5-FU Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer NCT06329973Phase 1, Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: Fruquintinib in combination with Sintilimab and CAPEOX QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ NCT07716449Phase 31 site๐Ÿ“ Beijing Qilu Pharmaceutical Co., Ltd. ยท Tests: QLS31905, Sintilimab, Oxaliplatin, Capecitabine Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma NCT06841679Phase 2, Phase 310 sites๐Ÿ“ Hialeah๐Ÿ“ Anyang๐Ÿ“ Guangzhou Beijing Biostar Pharmaceuticals Co., Ltd. ยท Tests: Utidelone Capsule, Utidelone Capsule, Utidelone Capsule, Fluoropyrimidine- and Platinum-containing Therapy, Oxaliplatin An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma NCT07018570Phase 21 site๐Ÿ“ Kashiwa National Cancer Center Hospital East ยท Tests: Pembrolizumab, Docetaxel, Oxaliplatin, Levofolinate, Fluorouracil (5-FU) Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06925243Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant apatinib combined with sintilimab and perioperative SOX, Neoadjuvant sintilimab combined with perioperativeโ€ฆ A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma NCT05687357Phase 23 sites๐Ÿ“ Wuhan๐Ÿ“ Nanjing๐Ÿ“ Taiyuan The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: Tislelizumab, S-1, Oxaliplatin, Nab paclitaxel, Radiation T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma NCT05894824Phase 1, Phase 21 site๐Ÿ“ Seoul Yonsei University ยท Tests: T-Dxd(Trastuzmab deruxtecan), Ramucirumab Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma NCT07700979Phase 325 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Denver Akeso ยท Tests: Cadonilimab, CAPOX regimen, Nivolumab, Placebo HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) NCT04447352Phase 315 sites๐Ÿ“ Aachen๐Ÿ“ Dresden๐Ÿ“ Frankfurt Krankenhaus Nordwest ยท Tests: 5-Fluorouracil, Leucovorin, Oxaliplatin, Docetaxel, Cisplatin Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma NCT07699939Phase 218 sites๐Ÿ“ Chiba๐Ÿ“ Fukuoka๐Ÿ“ Gifu National Cancer Center, Japan ยท Tests: serplulimab, Placebo A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06949033Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant cadonilimab combined with perioperative SOX, Neoadjuvant placebo plus perioperative SOX A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites๐Ÿ“ Orange๐Ÿ“ Santa Monica๐Ÿ“ Chicago Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil A Study of Sigvotatug Vedotin in Advanced Solid Tumors NCT04389632Phase 1158 sites๐Ÿ“ Anchorage๐Ÿ“ Fayetteville๐Ÿ“ Rogers Seagen, a wholly owned subsidiary of Pfizer ยท Tests: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatin A Study of PD-1 Inhibitors Combined With Fruquintinib and Chemotherapy in First-line Treatment of HER2-negative Advanced G/GEJ Cancer NCT06158919NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Fruquintinibใ€Nivolumabใ€Sintilimabใ€Oxaliplatinใ€Teysunoใ€Capecitabine Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 NCT07431281Phase 3314 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Anchorage AstraZeneca ยท Tests: Sonesitatug vedotin, Rilvegostomig, Nivolumab, Capecitabine, 5-Fluorouracil
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