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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Gastroesophageal Junction Adenocarcinoma

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer NCT06121700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antiโ€ฆ To Evaluate the Efficacy of CT041 in Sequential Treatment After First-line Treatment of Advanced Gastric/Esophagogastric Junction Adenocarcinoma NCT07179484n/a1 site๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: CT041 autologous CAR T-cell injection A Prospective Study on Esophagogastrostomy by an Innovative Surgical Technique NCT06300879NA1 site๐Ÿ“ Shanghai Huashan Hospital ยท Tests: Performing totally laparoscopic proximal gastrectomy with esophagogastrostomy by fissure technique AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer NCT06196697Phase 21 site๐Ÿ“ Harbin Harbin Medical University ยท Tests: Cadonilimab, Ivonescimab, XELOX, SOX Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer NCT05671822Phase 21 site๐Ÿ“ Shanghai Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A1811 and SHR-1701, SHR-A1811 and capecitabine, SHR-A181, SHR-1701, and capecitabine, SHR-A1811, SHR-1316, and capeโ€ฆ Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer NCT06962137Phase 26 sites๐Ÿ“ Antwerp๐Ÿ“ Brussels๐Ÿ“ Brussels Universitaire Ziekenhuizen KU Leuven ยท Tests: zolbetuximab, Retrospective cohort, no intervention SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer NCT07464756Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: SHR-1701, apatinib, S-1 & Oxaliplatin Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors NCT06947291Phase 21 site๐Ÿ“ Hangzhou CSPC ZhongQi Pharmaceutical Technology Co., Ltd. ยท Tests: Glumetinib Tablets, Docetaxel for Injection (Albumin-bound) A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Duarte Seagen, a wholly owned subsidiary of Pfizer ยท Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) SHR-1701 Combined With Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis NCT07384234Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: SHR-1701, Capecitabine, S-1, Paclitaxel, Oxaliplatin A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT07043400Phase 395 sites๐Ÿ“ Chandler๐Ÿ“ Los Alamitos๐Ÿ“ Colorado Springs BeOne Medicines ยท Tests: Subcutaneous Tislelizumab, Intravenous Tislelizumab, Cisplatin, Leucovorin, 5-fluorouracil (5-FU) Adebrelimab Combined With Nab-paclitaxel, Oxaliplatin and Tegafur (AOS) for Perioperative Treatment of Locally Advanced Resectable GC/GEJ NCT06808971Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Adebrelimab, Nab-paclitaxel, Oxaliplatin, Tegafur Gimeracil Oteracil Potassium Capsule First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dongying Qilu Hospital of Shandong University ยท Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin Neoadjuvant Iparomlimab and Tuvonralimab With Nab-P-SOX in Locally Advanced Gastric or Gastroesophageal Junction Cancer NCT07867392Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Iparomlimab and Tuvonralimab (QL1706), nab-P-SOX๏ผˆnab-paclitaxel, oxaliplatin, S-1๏ผ‰ A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites๐Ÿ“ Clovis๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach Bristol-Myers Squibb ยท Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma NCT07023315Phase 36 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Shijiazhuang Akeso ยท Tests: Cadonilimab, SOX chemotherapy, Placebo Assessing Iparomlimab and Tuvonralimab in Recurrent or Metastatic MSI-H/dMMR Gastric Cancer NCT07127822Phase 210 sites๐Ÿ“ Shijiazhuang๐Ÿ“ Harbin๐Ÿ“ Zhengzhou Peking University ยท Tests: Iparomlimab and Tuvonralimab, First line chemotherapy plus PD-1/PD-L1 antibody A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma NCT07069712Phase 270 sites๐Ÿ“ Newark๐Ÿ“ Washington D.C.๐Ÿ“ Fairway AstraZeneca ยท Tests: Sonesitatug Vedotin, Rilvegostomig, Trastuzumab Deruxtecan (T-DXd), Capecitabine, 5-Fluorouracil (5-FU) A Clinical Study of Sintilimab Combined With Chemothrapy Versus Chemotherapy as Adjuvant Therapy for Gastric/Gastroesophageal Junction Adenocarcinoma NCT07492615Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Sintilimab, S-1 & Oxaliplatin A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC) NCT07289997Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Iparomlimab and Tuvonralimab Injection (QL1706) Adebrelimab Plus Apatinib Combined With SOX Regimen as Conversion Therapy for Gastric Cancer NCT07353684Phase 21 site๐Ÿ“ Beijing Beijing Friendship Hospital ยท Tests: Adebrelimab, Apatinib, SOX Chemotherapy Evaluation, in Humans, of the Correlation Between Hepatotoxicity, Neurotoxicity Induced by Oxaliplatin, and Blood Levels of HMGB1 NCT06649474NA1 site๐Ÿ“ Clermont-Ferrand University Hospital, Clermont-Ferrand ยท Tests: assess the serum HMGB1 concentrations before and after an oxaliplatin-based chemotherapy SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT06649292Phase 31 site๐Ÿ“ Guangzhou Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A1904, Paclitaxel, Docetaxel, Irinotecan Safety and Short-term Outcomes of Modular Robotic System for Siewert II/III Gastroesophageal Junction Cancer NCT07790809NA1 site๐Ÿ“ Changchun The First Hospital of Jilin University ยท Tests: Robotic-assisted radical resection for Siewert type II/III gastroesophageal junction cancer Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma NCT06340711Phase 22 sites๐Ÿ“ New York๐Ÿ“ Philadelphia Weill Medical College of Cornell University ยท Tests: OBP-301, Pembrolizumab Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05) NCT05872685Phase 25 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou๐Ÿ“ Lishui Yu jiren ยท Tests: S1, Oxaliplatin, Serplulimab, Placebo
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