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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Grade II Glioma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma NCT04166409Phase 3132 sites📍 Birmingham📍 Mesa📍 Phoenix National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Echocardiography Test, Magnetic Resonance Imaging, Questionnaire Administration Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma NCT06410248Phase 11 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Magnetic Resonance Imaging, Questionnaire Administration, Resection, Temozolomide Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy NCT05180825Phase 225 sites📍 Amiens📍 Angers📍 Besançon University Hospital, Strasbourg, France · Tests: Trametinib, Vinblastine Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors NCT04479696NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Educational Intervention, Questionnaire Administration, Survey Administration, Video Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) NCT04485559Phase 117 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: Everolimus, Trametinib ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas NCT06838676Phase 220 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: ACT001 Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma NCT06831773NA1 site📍 Wuwei Gansu Wuwei Tumor Hospital · Tests: Carbon ion combined with photon radiotherapy Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared NCT07547163n/a1 site📍 Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Tests: Vorasidenib, Radiotherapy, active surveillance SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) NCT05303519Phase 361 sites📍 Birmingham📍 Phoenix📍 Phoenix Nuvation Bio Inc. · Tests: safusidenib, Placebo Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma NCT07091864NA3 sites📍 Phoenix📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Best Practice, Biospecimen Collection, Dietary Intervention, Glucose Measurement, Magnetic Resonance Imaging Vorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse Glioma NCT07240662n/a1 site📍 Heidelberg iOMEDICO AG · Tests: Vorasidenib Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma NCT04540107Phase 11 site📍 San Francisco Susan Chang · Tests: Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopic Imaging Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume) NCT06159478Phase 26 sites📍 Kashiwa📍 Sapporo📍 Kyoto National Cancer Center, Japan · Tests: Binimetinib 15 MG Implantable Microdevice In Primary Brain Tumors NCT04135807EARLY Phase 11 site📍 Boston Oliver Jonas · Tests: Microdevice Vorasidenib Maintenance for IDH Mutant Astrocytoma NCT06809322Phase 359 sites📍 Bedford Park📍 Camperdown📍 Heidelberg European Organisation for Research and Treatment of Cancer … · Tests: Vorasidenib, Vorasidenib Placebo Measure of the Potential Evoked by Electric Stimulation NCT02509442NA1 site📍 Montpellier University Hospital, Montpellier · Tests: Diffusion of direct electric stimulation Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas NCT05768919Phase 1, Phase 22 sites📍 Washington D.C.📍 Baltimore SignPath Pharma, Inc. · Tests: Treatment Period 1, Treatment Period 2, Treatment Period 3, Treatment Period 4a Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas NCT06687681Phase 21 site📍 Tehran Marzieh Ebrahimi · Tests: NK cell therapy Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas NCT04623931Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy, Temozolomide A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors NCT07243470Phase 1, Phase 212 sites📍 Angers📍 Angers📍 Bordeaux Centre Leon Berard · Tests: Tarlatamab, Temozolomide (TMZ) Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease NCT07703436Phase 212 sites📍 Los Angeles📍 San Francisco📍 New Haven Nuvation Bio Inc. · Tests: Safusidenib Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas NCT06381570EARLY Phase 11 site📍 Toronto Daniel Morgenstern · Tests: Tovorafenib, Vinblastine A Study of 177Lu-PSMA-617 in People With Gliomas NCT07223034Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Temozolomide, 177Lu-PSMA-617, 68Ga-PSMA-PET scan/ MRI, Quality of Life Questionnaires A Vaccine Trial for Low Grade Gliomas NCT02358187Phase 21 site📍 Pittsburgh James Felker · Tests: Experimental: HLA-A2 Restricted Glioma Antigen-Peptides with Poly-ICLC Short Term Outcomes After PRoton and PhotoN RadiOtherapy for IDH Mutated Grade 2 and 3 Gliomas NCT06180434n/a1 site📍 Rotterdam Erasmus Medical Center · Tests: proton therapy, photon therapy Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma NCT05964569Phase 21 site📍 Heidelberg University Hospital Heidelberg · Tests: model-guided optimization of treatment plan, standard treatment plan, no optimization Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma NCT06160206Phase 23 sites📍 Scottsdale📍 Jacksonville📍 Rochester Academic and Community Cancer Research United · Tests: Bevacizumab, Biospecimen Collection, Computed Tomography, Electronic Health Record Review, Hypofractionated Radiation T…
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