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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for HER2-negative Early Breast Cancer

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites📍 Birmingham📍 Scottsdale📍 Tucson QuantumLeap Healthcare Collaborative · Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Tras… Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NCT07214532NA49 sites📍 Phoenix📍 Scottsdale📍 Tucson Natera, Inc. · Tests: ctDNA-Guided Treatment Strategy Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies NCT07211178n/a16 sites📍 Birmingham📍 Whittier📍 Weston Tempus AI · Tests: There are no interventions in this observational study. Dalpicilib-Enhanced vs. Standard Endocrine Therapy in ER+ HER2- Early Breast Cancer NCT06637150Phase 31 site📍 Shanghai Fudan University · Tests: Dalpicilib, endocrine therapy A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer NCT06508216Phase 1, Phase 21 site📍 Villejuif Gustave Roussy, Cancer Campus, Grand Paris · Tests: Dato-DXd, Durvalumab Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC NCT06500208Phase 21 site📍 Shanghai Shanghai Jiao Tong University School of Medicine · Tests: Adebrelimab combined with nab-paclitaxel, epirubicin and cyclophosphamide Tirzepatide Weight Loss for MRD+ Early Breast Cancer NCT06517212Phase 21 site📍 Dallas Baylor Research Institute · Tests: Tirzepatide Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer NCT06375798n/a1 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: radiotherapy Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer NCT06341894Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Dalpiciclib, Endocrine therapy Neoadjuvant Camrelizumab and Fluzoparib and Nab-paclitaxel in Early Breast Cancer With HRR Gene Mutation NCT05761470Phase 21 site📍 Guangzhou Ying Lin · Tests: Camrelizumab, Fluzoparib, Nab-paclitaxel Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer NCT06106477NA1 site📍 Milwaukee Medical College of Wisconsin · Tests: Intermittent Fasting Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial NCT06042569Phase 23 sites📍 Duarte📍 Boston📍 Rochester City of Hope Medical Center · Tests: Cyclophosphamide, Docetaxel, Medical Chart Review, Questionnaire Administration ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer NCT06970912Phase 21 site📍 Beijing Peking University People's Hospital · Tests: Dalpiciclib + Aromatase Inhibitor with ctDNA-Guided Therapy, Taxane-Based Neoadjuvant Chemotherapy Dalpiciclib With or Without Entinostat and Letrozole in HR+/HER2- Early Breast Cancer NCT07492394Phase 21 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: entinostat, Dalpiciclib, Letrozole Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy NCT05989347Phase 11 site📍 New Haven Yale University · Tests: Dapagliflozin 10mg Chemotherapy Combined With Bevacizumab Neoadjuvant Therapy for HER2-negative Breast Cancer NCT05525767Phase 41 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: Bevacizumab Ablation Compare With Surgery for Early Breast Cancer NCT07484087NA1 site📍 Beijing Peking University People's Hospital · Tests: breast conserving surgery, cryo-thermal ablation Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial NCT07407920Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Biospecimen Collection, Hormone Therapy, Pembrolizumab, Pertuzumab, Trastuzumab A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence NCT06492616Phase 3567 sites📍 Daphne📍 Chandler📍 Gilbert Stemline Therapeutics, Inc. · Tests: Elacestrant, Anastrozole, Letrozole, Exemestane, Tamoxifen Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer NCT05020860Phase 22 sites📍 Houston📍 Houston Baylor Breast Care Center · Tests: Paclitaxel, Carboplatin, Trastuzumab, Pertuzumab, Doxorubicin fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases NCT06328465NA1 site📍 Milan European Institute of Oncology · Tests: Diffusion whole body MRI NEODOXy: Targeting Breast Cancer Stem Cells With Doxycycline NCT06452394Phase 28 sites📍 Sankt Gallen📍 Genolier📍 Winterthur Swiss Cancer Institute · Tests: Doxycyclin Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer NCT06518837Phase 27 sites📍 Elizabeth📍 Hamilton📍 Livingston Rutgers, The State University of New Jersey · Tests: Tirzepatide Addition of Cisplatin to Adjuvant Chemotherapy for Early Stage Breast Cancer in High-Risk Women NCT03201861Phase 31 site📍 Shanghai RenJi Hospital · Tests: Paclitaxel, Cisplatin, EC to docetaxel or paclitaxel Impact of Exercise on Quality of Life of EBC Patients on Treatment With Adjuvant AI With or Without CDK4/6 Inhibitors NCT07215364NA5 sites📍 L'Hospitalet de Llobregat📍 Pamplona📍 Granada Spanish Breast Cancer Research Group · Tests: Training program Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer NCT06534125NA4 sites📍 Atlanta📍 Atlanta📍 Atlanta Emory University · Tests: Acupressure Therapy, Acupuncture Therapy, Aromatase Inhibition Therapy, Discussion, Survey Administration Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for Human Epidermal Growth Factor Receptor 2 (HER2) Negative Early Breast Cancer Patients NCT04836156Phase 1, Phase 21 site📍 Beijing Peking University People's Hospital · Tests: neoadjuvant chemotherapy upon in vitro PTC drug sensitivity screening for triple negative breast cancer, neoadjuvant ch… Preoperative Immunotherapy Combined With Stereotactic Radiation Therapy Boost in the Treatment of HER2-negative Breast Cancer NCT06472583Phase 21 site📍 Gliwice Maria Sklodowska-Curie National Research Institute of Oncol… · Tests: Keytruda, Preoperative radiation therapy, Placebo Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer NCT04576143Phase 2, Phase 31 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: Epirubicin, Cyclophosphamid, Docetaxel, Paclitaxel CDK4/6 Inhibitors Combined With Endocrine Therapy for Neoadjuvant Treatment NCT07366112Phase 21 site📍 Beijing Peking University People's Hospital · Tests: CDK4/6 inhibitor with endocrine therapy
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