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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HFpEF - Heart Failure With Preserved Ejection Fraction

Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction NCT06803849n/a1 site📍 Moscow National Medical Research Center for Therapy and Preventive… Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site📍 Leeds University of Leeds SHort Of Pace - Heart Failure (SHOP-HF) NCT06992089NA1 site📍 Valencia Fundación para la Investigación del Hospital Clínico de Val… · Tests: Dual-chamber cardiac pacemaker (Essentio MRI L111 Boston Scientific®), Single-chamber cardiac pacemaker (Essentio MRI L… Assessment of CCM in HF With Higher Ejection Fraction NCT05064709NA67 sites📍 Birmingham📍 Mesa📍 Mesa Impulse Dynamics · Tests: Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, OPTIMIZER™ Smart Mini System Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF NCT05577819NA1 site📍 Boston Massachusetts General Hospital · Tests: 99mTc-pyrophosphate Scintigraphy Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site📍 Edegem University Hospital, Antwerp · Tests: Conduction system pacing, Right ventricular apical pacing Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction NCT02901184Phase 378 sites📍 Alexander City📍 Birmingham📍 Tucson Uppsala University · Tests: Spironolactone, Standard care CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation NCT06762964Phase 21 site📍 Rochester Mayo Clinic · Tests: Dapagliflozin tablet, Placebo Tablet Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction NCT07178145Phase 41 site📍 Charlottesville University of Virginia · Tests: GLP-1RA AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites📍 Orange📍 Pasadena📍 Detroit Peerbridge Health, Inc · Tests: 15-minutes of sitting during COR ECG Acquistion Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction NCT07401771n/a1 site📍 Rochester Mayo Clinic · Tests: Exercise Cardiovascular Magnetic Resonance Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF NCT04592445NA26 sites📍 Birmingham📍 Phoenix📍 La Jolla Axon Therapies, Inc. · Tests: Greater Splanchnic Nerve Ablation, Sham Control MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction NCT06670001NA1 site📍 Philadelphia University of Pennsylvania · Tests: Gamification plus social incentive, Gamification plus competition Renal Denervation in Patients With Atrial Fibrillation and Hypertension NCT07893821NA1 site📍 London Pavel Antiperovitch · Tests: Catheter-based renal artery electrical stimulation (as a feasibility assessment for renal denervation) Acute Heart Failure With Preserved Ejection Fraction - COngestion Discharge Evaluation NCT04343430NA1 site📍 Vandœuvre-lès-Nancy Central Hospital, Nancy, France · Tests: Clinical examination centered on congestion, Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and li… Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction NCT06517186n/a6 sites📍 Chicago📍 Baltimore📍 Boston Northwestern University The Prognostic Role and Diagnostic Efficacy of Exercise Right Heart Catheterization With a Simultaneous Echocardiography in Patients With Dyspnea on Exertion NCT05490901n/a1 site📍 Seoul Samsung Medical Center · Tests: Exercise hemodynamic test UK Heart Failure With Preserved Ejection Fraction NCT05441839n/a26 sites📍 Abercynon📍 Aylesbury📍 Birmingham Manchester University NHS Foundation Trust Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? NCT07295522Phase 412 sites📍 San Donato Milanese📍 Ancona📍 Cecina IRCCS Policlinico S. Donato · Tests: Guideline-Directed Medical Therapy (GDMT) Copenhagen Heart Failure With Preserved Ejection Fraction NCT06685237n/a1 site📍 Hellerup Tor Biering-Sørensen A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) NCT06991257Phase 2150 sites📍 Beverly Hills📍 Lake Forest📍 Santa Maria Pfizer · Tests: Placebo, Low Dose PF-07328948, Medium Dose PF-07328948, High Dose PF-07328948 Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial NCT06065124NA2 sites📍 Arnhem📍 Groningen University Medical Center Groningen · Tests: Bariatric surgery strategy SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan NCT05057806EARLY Phase 11 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Empagliflozin 25 MG, Placebo Purinergic Signaling and the Postmenopausal Heart NCT06015776n/a1 site📍 Boston Beth Israel Deaconess Medical Center · Tests: Gender Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication NCT07272902NA4 sites📍 Halifax📍 Hamilton📍 London Nova Scotia Health Authority · Tests: Catheter Ablation for Atrial Fibrillation, Rate Control Medications (beta-blockers, calcium channel blockers, digoxin) Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR NCT07185100n/a1 site📍 Berlin German Heart Institute SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial NCT05138575Phase 21 site📍 Philadelphia University of Pennsylvania · Tests: Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction NCT07123779Phase 1, Phase 23 sites📍 Kansas City📍 Greenville📍 Dallas 35Pharma Inc., a GSK company · Tests: HS235, Placebo Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) NCT06560762Phase 12 sites📍 Chicago📍 Dallas Secretome Therapeutics · Tests: STM01 Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants NCT05838287Phase 41 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Pioglitazone, Placebo
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