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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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21 recruiting trials

for HGG

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFYยฎ+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma NCT05645107Phase 362 sites๐Ÿ“ Bullhead City๐Ÿ“ Huntington Park๐Ÿ“ St. Petersburg Grifols Therapeutics LLC ยท Tests: Xembify, Placebo A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations NCT05503797Phase 270 sites๐Ÿ“ Beverly Hills๐Ÿ“ San Francisco๐Ÿ“ Westwood, Los Angeles Fore Biotherapeutics ยท Tests: Plixorafenib CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults NCT06305910Phase 11 site๐Ÿ“ Minneapolis OX2 Therapeutics ยท Tests: Treatment with CD200AR-L A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma NCT07710690Phase 13 sites๐Ÿ“ Shanghai๐Ÿ“ Wuhan๐Ÿ“ Xi'an Neuregen Therapeutics Co., Ltd. ยท Tests: NRG-103 Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rฮฑ2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDGโ€ฆ Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) NCT04485559Phase 117 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ San Diego University of California, San Francisco ยท Tests: Everolimus, Trametinib Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection NCT06018363Phase 1, Phase 21 site๐Ÿ“ Suzhou Dushu Lake Hospital Affiliated to Soochow University ยท Tests: Allogenic B7-H3 CAR-ฮณฮดT cell(QH104) Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) NCT07210632EARLY Phase 11 site๐Ÿ“ Nashville Eben Rosenthal ยท Tests: Nivolumab, Nivolumab-IRDye800 Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Chicago Nationwide Children's Hospital ยท Tests: Ribociclib, Everolimus, Temozolomide (TMZ) Intracranial Genetically Modified Immune Cells (TGFฮฒR2KO/IL13Rฮฑ2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma NCT06815029Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Echocardiography, Fludeoxyglucose F-18, Intracranial โ€ฆ Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site๐Ÿ“ Toronto Sunnybrook Health Sciences Centre ยท Tests: Focused Ultrasound Next Generation Dome Helmet, Definityยฎ Vial for (Perflutren Lipid Microsphere) Injectable Suspension NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site๐Ÿ“ Washington D.C. Children's National Research Institute ยท Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma NCT07061626Phase 11 site๐Ÿ“ Chicago Cerenome ยท Tests: Rhenium-186 Nanoliposome A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions NCT06072586EARLY Phase 12 sites๐Ÿ“ Chandler๐Ÿ“ Phoenix St. Joseph's Hospital and Medical Center, Phoenix ยท Tests: BDTX-1535, BDTX-1535 combined with radiation therapy, BDTX-1535 combined with temozolomide and radiation therapy A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG) NCT06519682NA1 site๐Ÿ“ Toronto Daniel Morgenstern ยท Tests: Nivolumab, Radiation 18F-Fluciclovine PET-MRI in High-grade Glioma NCT05553041EARLY Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: 18F-Fluciclovine PET-MRI PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma NCT05096481Phase 213 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Miami Nationwide Children's Hospital ยท Tests: PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors NCT06528691Phase 26 sites๐Ÿ“ Memphis๐Ÿ“ Barretos๐Ÿ“ Sรฃo Paulo St. Jude Children's Research Hospital ยท Tests: Entrectinib, Cyclophosphamide, Etoposide, Carboplatin, G-CSF A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors NCT06357377Phase 11 site๐Ÿ“ Orange Neonc Technologies, Inc. ยท Tests: NEO100 Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. NCT07439172Phase 21 site๐Ÿ“ Camden The Cooper Health System ยท Tests: Pre-radiation temozolomide. Study of Olutasidenib and Temozolomide in HGG NCT06161974Phase 220 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Miami Rigel Pharmaceuticals ยท Tests: Olutasidenib + TMZ
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