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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Head and Neck Carcinoma

Tirelizumab in Combination With Carboplatin and Albumin-binding Paclitaxel for Neoadjuvant Therapy in HNSCC NCT05941338Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Tirelizumab ,+Carboplatin+albumin-bound paclitaxel VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) NCT06780111Phase 1, Phase 252 sites๐Ÿ“ Pittsburgh๐Ÿ“ Natal๐Ÿ“ Porto Alegre Merck Sharp & Dohme LLC ยท Tests: Pembrolizumab, I-DXd, Leucovorin, Levoleucovorin, 5-Fluorouracil (5-FU) A Dose Optimization/Expansion Study of SAR445877 in Adult Chinese Participants With Advanced Gastric or Gastroesophageal Junction Cancer NCT07692204Phase 21 site๐Ÿ“ Shanghai Sanofi ยท Tests: SAR445877 Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma NCT06606028n/a1 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Blood Specimen Collection, Tumor Tissue Collection, Medical Record Review Postoperative Radiotherapy Followed by Immunotherapy for Locally Advanced Esophageal Carcinoma NCT05937438Phase 1, Phase 21 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Immune Checkpoint Inhibitors Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid Carcinoma NCT07218315NA2 sites๐Ÿ“ Sarasota๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: CellFX nsPFA Percutaneous Electrode System Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002) NCT04807140Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Toripalimab, nab-paclitaxel, carboplatin, Toripalimab, Surgical resection A Study of MT-4561 in Patients With Various Advanced Solid Tumors NCT06943521Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Columbus Tanabe Pharma America, Inc. ยท Tests: MT-4561 A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma NCT06843889Phase 21 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: Toripalimab (240mg day1, Q3W*3cycle) Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers NCT05553782EARLY Phase 12 sites๐Ÿ“ Boston๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Implantable Microdevice (IMD) 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors NCT07557225NA1 site๐Ÿ“ Beijing Peking University First Hospital ยท Tests: 18F-T2 PET/CT Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC) NCT07485296Phase 21 site๐Ÿ“ Rozzano Gruppo Oncologico del Nord-Ovest ยท Tests: Postbiotix-HLAโ„ข is a food supplement based on fermented FOS from Lactobacillus paracasei CNCM I-5220 postbiotic., placeโ€ฆ Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma NCT06476067n/a2 sites๐Ÿ“ Nagoya๐Ÿ“ Chลซล City of Hope Medical Center ยท Tests: Surgery A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer NCT06385080Phase 1, Phase 256 sites๐Ÿ“ La Jolla๐Ÿ“ Aurora๐Ÿ“ New Haven Janssen Research & Development, LLC ยท Tests: Amivantamab, Pembrolizumab, Paclitaxel, Carboplatin Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers NCT04747054Phase 326 sites๐Ÿ“ Avignon๐Ÿ“ Besanรงon๐Ÿ“ Bordeaux UNICANCER ยท Tests: Pembrolizumab, Loco-regional radiotherapy, Chemotherapy Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus NCT05918510n/a1 site๐Ÿ“ Rome Regina Elena Cancer Institute ยท Tests: Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy NCT05892354NA20 sites๐Ÿ“ Fuzhou๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou First Affiliated Hospital of Guangxi Medical University ยท Tests: Enteral immunonutrition, Standard enteral nutrition Epstein-Barr Virus Antibody and Epstein-Barr Virus DNA for Nasopharyngeal Carcinoma Screening NCT05447169n/a1 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: EBV antibodies test, EBV DNA test Establishment of a Microfluidic Based Liquid Biopsy Platform for Recurrent/Metastatic Head and Neck Cancers Prognostication Using NK Cell IFN-ฮณ Expression and CTM Correlation With DS-SACA Chip NCT06678724n/a1 site๐Ÿ“ Zhubei National Taiwan University Hospital Toripalimab Plus Surgery vs Surgery Alone for Resectable Recurrent Nasopharyngeal Carcinoma NCT04778956Phase 37 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab, salvage surgery CONFIRM: Magnetic Resonance Guided Radiation Therapy NCT04368702NA2 sites๐Ÿ“ Boston๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Viewray MRIdianยฎ Linac AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy NCT06494995Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Cadonilimab, Low-dose radiotherapy, SBRT, Capecitabine Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell Carcinoma NCT06988956Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Nimotuzumab, Tegafur, radiotherapy AB122 Platform Study NCT04999761Phase 19 sites๐Ÿ“ Aichi๐Ÿ“ Chiba๐Ÿ“ Ehime Taiho Pharmaceutical Co., Ltd. ยท Tests: AB122, AB122, TAS-116, TAS-120, TAS-115 A Phase II Study of Anlotinib + PD-1 Inhibitor vs. PD-1 Inhibitor Maintenance After First-Line Chemoimmunotherapy in Advanced ESCC (Esophageal Squamous Cell Carcinoma) NCT07863141Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: anlotinib + PD-1 inhibitor, PD-1 inhibitor Surufatinib Combined with Envolizumab As Second-line Treatment for Recurrent/Metastatic HNSCC NCT06876844Phase 21 site๐Ÿ“ Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaโ€ฆ ยท Tests: combination of Surufatinib and Envolizumab A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors NCT07814248Phase 13 sites๐Ÿ“ Maumee๐Ÿ“ Portland๐Ÿ“ Fairfax TwoStep Therapeutics, Inc. ยท Tests: TS-104 Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT)
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