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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure, Systolic

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036) NCT05714085Phase 2, Phase 3111 sites📍 Los Angeles📍 Palo Alto📍 San Bernardino Merck Sharp & Dohme LLC · Tests: Vericiguat tablet, Vericiguat suspension, Placebo tablet, Placebo suspension Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure NCT07199088NA1 site📍 Chak Eighty-seven -Twelve Left University of Health Sciences Lahore · Tests: Acetazolamide, Metolazone Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Ketone Monoester (KE) Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure NCT07467668NA1 site📍 Pleasanton Kaiser Permanente · Tests: Notification Group, No Notification Group ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing NCT06324682n/a31 sites📍 Ferrara📍 Arezzo📍 Bologna University Hospital of Ferrara · Tests: Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchron… Biomarkers for Left Ventricular Reverse Remodeling in Heart Failure (REVERT-HF) NCT07701876n/a1 site📍 Shanghai Ruijin Hospital Luwan Branch Paced Heart Rate Acceleration for Cardiac Conditioning NCT06332391NA1 site📍 Iowa City Denice Hodgson-Zingman, MD · Tests: Exercise-similar cardiac pacing, Sham cardiac pacing Mechanistic Clinical Trial of Advanced Imaging for CRT NCT03398369NA1 site📍 Charlottesville University of Virginia · Tests: CMR/CTA Guidance for CRT Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD NCT03836482NA1 site📍 Ann Arbor SeaStar Medical · Tests: Selective Cytopheretic Device Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure NCT07430553NA1 site📍 London Imperial College London · Tests: Biventricular pacing, Conduction system pacing, Left bundle optimised cardiac resynchronisation therapy Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance NCT07131631n/a6 sites📍 Minneapolis📍 Charlotte📍 Cincinnati Minneapolis Heart Institute Foundation · Tests: Cardiac MRI Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure NCT07209098n/a1 site📍 Marlton Impulse Dynamics · Tests: Cardiac Contractility Modulation (CCM) A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure NCT06671015NA1 site📍 New Haven Yale University · Tests: Airvo 3 Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction NCT04703842Phase 1, Phase 25 sites📍 San Diego📍 San Francisco📍 St Louis Sardocor Corp. · Tests: SRD-001, Placebo Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) NCT07347197Phase 1, Phase 25 sites📍 Tsukuba📍 Kawasaki📍 Matsumoto Heartseed Inc. · Tests: HS-005 Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery NCT05632432NA1 site📍 Helsinki Hospital District of Helsinki and Uusimaa · Tests: Epicardial AAMs-patch transplantation, RNA-stabilized whole blood sampling, Plasma sampling, Transthoracic echocardiogr… IRONHEART: Intravenous Iron in Non-ischaemic Heart Failure NCT06542822n/a1 site📍 Southampton University Hospital Southampton NHS Foundation Trust · Tests: Ferric derisomaltose Cardiac Contractility Modulation in Chagas Heart Disease NCT05519046NA1 site📍 São Paulo InCor Heart Institute · Tests: Cardiac Contractility Modulation (CCM), CRT RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases NCT07491237n/a1 site📍 Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: speckle tracking echocardiography Echocardiography-Based Predictors of Outcomes in Hospitalized Patients With Decompensated Heart Failure (ECHO-DECOMP) NCT07439159n/a1 site📍 Istanbul Istanbul University - Cerrahpasa pErsonalised Nocebo Assessment of Beta-blockEr Symptoms in Heart Failure NCT07029906NA1 site📍 London Imperial College London · Tests: Bisoprolol 2.5 mg, Placebo A Study of LY3971297 in Participants With Heart Failure NCT07547540Phase 111 sites📍 Detroit📍 St Louis📍 Chapel Hill Eli Lilly and Company · Tests: LY3971297, LY3971297, Placebo, Placebo Digoxin After Acute Heart Failure (DIG-DICA) NCT07321509Phase 41 site📍 Buenos Aires Hospital General de Agudos "Dr. Cosme Argerich" · Tests: Usual Care, Digoxin INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery NCT06965504NA17 sites📍 Tampa📍 Indianapolis📍 Minneapolis Abiomed Inc. · Tests: Impella 5.5 SmartAssist Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation NCT06805253n/a2 sites📍 Moscow📍 Voronezh Petrovsky National Research Centre of Surgery · Tests: Not applicable - observational study Developing a Digital Aid to Improve ICD Decisions NCT07084142NA2 sites📍 San Francisco📍 Greenville Stanford University · Tests: Online, patient-facing decision-making aid (app) with personalized risk information., Implantable Cardioverter Defibril… Study to Assess Safety and Efficacy of Treating Symptomatic, Ischemic, Chronic Congestive Heart Failure Patients with an LVEF of ≤40% with Fresh, Uncultured, Autologous, Adipose-derived Regenerative Cells Isolated from Lipoaspirate. NCT06705023Phase 21 site📍 Astana Ralf Rothoerl · Tests: Uncultured, autologous, adipose-derived regenerative cells (UA-ADRCs), Continuation of patient's best guideline ba… The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) NCT05427370NA46 sites📍 Los Angeles📍 New Haven📍 Louisville Sunnybrook Health Sciences Centre · Tests: Revascularization by PCI, Revascularization by CABG Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing NCT07526896NA1 site📍 Minneapolis Medtronic Cardiac Rhythm and Heart Failure · Tests: LBBAP Therapy, LOT-CRT, ICD, LOT-CRT Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure NCT06270498Phase 41 site📍 Pisa Raffaele De Caterina · Tests: Sucrosomial iron, Placebo
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