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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure With Preserved Ejection Fraction (HFPEF)

Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction NCT06803849n/a1 site๐Ÿ“ Moscow National Medical Research Center for Therapy and Preventiveโ€ฆ Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site๐Ÿ“ Leeds University of Leeds Assessment of CCM in HF With Higher Ejection Fraction NCT05064709NA67 sites๐Ÿ“ Birmingham๐Ÿ“ Mesa๐Ÿ“ Mesa Impulse Dynamics ยท Tests: Cardiac Contractility Modulation Therapy via OPTIMIZERโ„ข Smart Mini System, OPTIMIZERโ„ข Smart Mini System Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF NCT05577819NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: 99mTc-pyrophosphate Scintigraphy Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction NCT02901184Phase 378 sites๐Ÿ“ Alexander City๐Ÿ“ Birmingham๐Ÿ“ Tucson Uppsala University ยท Tests: Spironolactone, Standard care CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation NCT06762964Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Dapagliflozin tablet, Placebo Tablet Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction NCT07178145Phase 41 site๐Ÿ“ Charlottesville University of Virginia ยท Tests: GLP-1RA AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites๐Ÿ“ Orange๐Ÿ“ Pasadena๐Ÿ“ Detroit Peerbridge Health, Inc ยท Tests: 15-minutes of sitting during COR ECG Acquistion Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF NCT04592445NA26 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ La Jolla Axon Therapies, Inc. ยท Tests: Greater Splanchnic Nerve Ablation, Sham Control MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction NCT06670001NA1 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: Gamification plus social incentive, Gamification plus competition Renal Denervation in Patients With Atrial Fibrillation and Hypertension NCT07893821NA1 site๐Ÿ“ London Pavel Antiperovitch ยท Tests: Catheter-based renal artery electrical stimulation (as a feasibility assessment for renal denervation) Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction NCT06517186n/a6 sites๐Ÿ“ Chicago๐Ÿ“ Baltimore๐Ÿ“ Boston Northwestern University UK Heart Failure With Preserved Ejection Fraction NCT05441839n/a26 sites๐Ÿ“ Abercynon๐Ÿ“ Aylesbury๐Ÿ“ Birmingham Manchester University NHS Foundation Trust Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? NCT07295522Phase 412 sites๐Ÿ“ San Donato Milanese๐Ÿ“ Ancona๐Ÿ“ Cecina IRCCS Policlinico S. Donato ยท Tests: Guideline-Directed Medical Therapy (GDMT) Copenhagen Heart Failure With Preserved Ejection Fraction NCT06685237n/a1 site๐Ÿ“ Hellerup Tor Biering-Sรธrensen Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication NCT07272902NA4 sites๐Ÿ“ Halifax๐Ÿ“ Hamilton๐Ÿ“ London Nova Scotia Health Authority ยท Tests: Catheter Ablation for Atrial Fibrillation, Rate Control Medications (beta-blockers, calcium channel blockers, digoxin) Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR NCT07185100n/a1 site๐Ÿ“ Berlin German Heart Institute SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial NCT05138575Phase 21 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) NCT06560762Phase 12 sites๐Ÿ“ Chicago๐Ÿ“ Dallas Secretome Therapeutics ยท Tests: STM01 Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants NCT05838287Phase 41 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Pioglitazone, Placebo Predictors of Poor Prognosis in HFpEF NCT06844032n/a1 site๐Ÿ“ Moscow National Medical Research Center for Cardiology, Ministry oโ€ฆ Can Tiny Bubbles Offer an Alternative to Catheters for Assessing Pressures Inside the Heart? Investigating Ultrasound Contrast Agents as Pressure Sensors Against Gold Standard Catheter Pressures in Cardiac Catheterisation Patients. NCT07416279NA1 site๐Ÿ“ London King's College London ยท Tests: Contrast Echocardiography Inspiratory Muscle Training in HFpEF NCT06510231NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Inspiratory Muscle Training Cardiovascular and Renal Endpoints With Flozins - an Observational Prospective Study in CKD HFpEF Patients NCT07237451n/a1 site๐Ÿ“ Iaศ™i Grigore T. Popa University of Medicine and Pharmacy ยท Tests: Arterial stiffness, Echocardiography, Biomarkers determination, NMR metabolomics and uremic toxins mapping Stroke Risk Assessment and Markers of Blood Clotting in Patients With Newly Diagnosed Non-valvular Atrial Fibrillation (NVAF), Who Have Not Received Oral Anticoagulation Therapy (OAC-therapy) Prior to Inclusion NCT06949319n/a1 site๐Ÿ“ Esbjerg Nedim Tojaga AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices NCT06909682n/a1 site๐Ÿ“ Salerno University of Salerno ยท Tests: Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up Incretin Therapies in Obesity-related HFpEF NCT07554638Phase 41 site๐Ÿ“ New York Columbia University ยท Tests: Tirzepatide Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction NCT07634640EARLY Phase 11 site๐Ÿ“ Gainesville University of Florida ยท Tests: Ferumoxytol infusion Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition NCT04822649NA1 site๐Ÿ“ Seoul Korea University Anam Hospital ยท Tests: Adenosine stress echocardiography with the evaluation of coronary artery blood flow A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF NCT07761117Phase 3679 sites๐Ÿ“ Fairhope๐Ÿ“ Anchorage๐Ÿ“ Gilbert AstraZeneca ยท Tests: Elecoglipron, Placebo
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