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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure With Reduced Ejection Fraction (HFrEF)

S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction NCT05553886Phase 31 site📍 Shenzhen Shenzhen People's Hospital · Tests: To evaluate whether the efficacy of the study drug is noninferior to that of the positive control drug Vericiguat and Reverse Remodeling Indices in Heart Failure NCT07405944Phase 44 sites📍 Izola📍 Ljubljana📍 Ljubljana University Medical Centre Ljubljana · Tests: Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT) Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site📍 Leeds University of Leeds Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL) NCT07269366NA1 site📍 Groningen University Medical Center Groningen · Tests: CABG, PCI Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF) NCT07702760n/a1 site📍 Rotterdam Jasper Brugts MD PhD Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure NCT07259512Phase 41 site📍 Kartasura Evi Liliek Wulandari · Tests: Ramipril Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Ketone Monoester (KE) Alleviant ALLAY-HFrEF Study NCT06812533NA70 sites📍 Los Angeles📍 Los Angeles📍 Sacramento Alleviant Medical, Inc. · Tests: Alleviant ALV1 System, Sham-Control Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction NCT07644806NA1 site📍 Norfolk Old Dominion University · Tests: Extra-virgin olive oil AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites📍 Orange📍 Pasadena📍 Detroit Peerbridge Health, Inc · Tests: 15-minutes of sitting during COR ECG Acquistion Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site📍 Edegem University Hospital, Antwerp · Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dy… Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? NCT07295522Phase 412 sites📍 San Donato Milanese📍 Ancona📍 Cecina IRCCS Policlinico S. Donato · Tests: Guideline-Directed Medical Therapy (GDMT) Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF NCT06384963NA3 sites📍 Adelaide📍 Melbourne📍 Hamilton Ceryx Medical Australia · Tests: Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting NCT06148935n/a1 site📍 Multiple Locations Bayer · Tests: Vericiguat (Verquvo, BAY1021189) Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With Reduced and Mildly Reduced Ejection Fraction NCT07741305n/a5 sites📍 Bari📍 Milan📍 Pavia Istituti Clinici Scientifici Maugeri SpA Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp) NCT06689111NA1 site📍 Pátrai University Hospital of Patras · Tests: Left bundle branch pacing lead, CRT with the standard method through cs Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF NCT06078436NA1 site📍 Seoul Min-Seok Kim · Tests: Pulmonary artery catheter Atrial Shunt for the Treatment of Heart Failure With Reduced Ejection Fraction NCT07820410Phase 2, Phase 31 site📍 Beijing Beijing Anzhen Hospital · Tests: D-shant Atrial Shunt, Guideline-Directed Medical Therapy (GDMT) for heart failure with reduced ejection fraction Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction NCT04703842Phase 1, Phase 25 sites📍 San Diego📍 San Francisco📍 St Louis Sardocor Corp. · Tests: SRD-001, Placebo Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure NCT06831825Phase 11 site📍 Houston Medley Therapeutics · Tests: YAP101 (AAV9-Sav-shRNA) AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices NCT06909682n/a1 site📍 Salerno University of Salerno · Tests: Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up Heart Failure Management for Patient With CIED Remotely Monitored NCT07247032NA1 site📍 Paris Implicity · Tests: SmartSignalHF, HF RM standard of care Telemedicine-guided Uptitration of Therapy in Chronic Heart Failure NCT07518030NA1 site📍 Piacenza Azienda Unita Sanitaria Locale di Piacenza · Tests: Telemedicine-based follow-up, Standard follow-up HFrEF Polypill in Sri Lanka RCT NCT07569640Phase 312 sites📍 Kandy📍 Anuradhapura📍 Kurunegala Washington University School of Medicine · Tests: Usual Care, HFrEF Polypill Telemonitoring to Optimize Medication Titration for Heart Failure: a Feasibility Study NCT07016815NA2 sites📍 Hong Kong📍 Hong Kong Chinese University of Hong Kong · Tests: Wearable wrist heart rate and activity monitor, Bluetooth enabled body weight scale with bioimpedance analysis, Bluetoo… Impact of Barostimulation on Hemodynamics in Adults With Heart Failure NCT07335510NA7 sites📍 San Francisco📍 Washington D.C.📍 Chicago Columbia University · Tests: Baroreflex Activation Therapy Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients NCT07167368NA1 site📍 Nantong Haiyan Pan · Tests: Standardized Basic Drug Therapy for HFrEF with Chronic Kidney Dysfunction, Home-based Personalized Exercise Rehabilitat… Vsling™ III: Clinical Evaluation of the Vsling™ Device for Ventricular Repair in Patients With Heart Failure NCT06002386NA1 site📍 Krakow Cardiac Success · Tests: Vsling Ketones, SGLT2, HFrEF NCT06229678EARLY Phase 11 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Empagliflozin 25 MG Oral Tablet, Placebo, Acipimox 250 Mg Oral Capsule Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF NCT07347925n/a1 site📍 Al Mansurah Future University in Egypt · Tests: Prehospital ARNI use, No prehospital ARNI use
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