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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for High-risk Prostate Cancer

24 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer NCT05936736NA1 site📍 Milan IRCCS San Raffaele · Tests: prostate SBRT SRT Versus SRT+ADT in Prostate Cancer NCT05019846Phase 31 site📍 Brescia Marco Lorenzo Bonu · Tests: Triptorelin Embonate, Bicalutamide 50 mg Delayed Pelvic Imaging With [68]Ga-PSMA PET/CT in a Patient With High-risk Prostate Cancer. NCT07357259NA1 site📍 Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna · Tests: Intervention Group Adjuvant Rezvilutamide Monotherapy for High-Risk Prostate Cancer After Radical Prostatectomy NCT07711314Phase 21 site📍 Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Unive… · Tests: Rezvilutamide Tablets Phase III Adaptive Adaptive Stereostactic Body Radiotherapy (SBRT) With Dose Escalation for High-Risk Prostate Cancer NCT07189598NA1 site📍 Rennes Center Eugene Marquis · Tests: Adaptive Stereostatic Body RadioTherapy (SBRT) including both Whole Pelvic RadioTherapy (WPRT) and dose-escalation on t… Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer NCT07325721Phase 21 site📍 Charleston Medical University of South Carolina · Tests: Hypofractionated radiation with a microboost High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins NCT06835426NA1 site📍 Ghent Algemeen Ziekenhuis Maria Middelares · Tests: Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen im… Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy NCT06056830Phase 334 sites📍 Birmingham📍 Phoenix📍 Little Rock Clarity Pharmaceuticals Ltd · Tests: 64Cu-SAR-bisPSMA Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era NCT06508567NA1 site📍 Toronto University Health Network, Toronto · Tests: High Dose Rate Brachytherapy Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer NCT04725903NA1 site📍 Atlanta Emory University · Tests: High-Dose Rate Brachytherapy, Proton Beam Radiation Therapy, Quality-of-Life Assessment, Survey Administration Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial NCT06499870Phase 21 site📍 Chicago Sean Sachdev · Tests: Biopsy, Biospecimen Collection, Computed Tomography, Enzalutamide, Fluorine F 18 Piflufolastat Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease NCT03836196NA1 site📍 Vancouver British Columbia Cancer Agency · Tests: LDR Brachytherapy and External Beam Radiation Therapy Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI NCT04954599Phase 1, Phase 25 sites📍 Brussels📍 Ghent📍 Maastricht Maastricht University Medical Center · Tests: CP-506, Carboplatin, Immune checkpoint inhibitor ¹⁸F-PSMA-1007 PET-CT-Directed Focal Therapy for MRI-Invisible Prostate Cancer NCT07788625NA1 site📍 Hong Kong The University of Hong Kong · Tests: Focal Therapy for Prostate Cancer Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer NCT02526368EARLY Phase 11 site📍 San Francisco Ivan de Kouchkovsky, MD · Tests: Hyperpolarized 13C-Pyruvate, Hyperpolarized 13C,15N2-urea, Magnetic Resonance Spectroscopic Imaging High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe) NCT07223385Phase 21 site📍 Los Angeles Cedars-Sinai Medical Center · Tests: Cardio-Oncology Referral, Notification to PCP/General Cardiologist Safety and Early Efficacy of Radical Prostatectomy for Newly Diagnosed Very High Risk Locally Advanced and Oligometastatic Prostate Cancer NCT02971358NA1 site📍 Vienna Medical University of Vienna · Tests: Radical prostatectomy Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer NCT06059118Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: DFMO, testosterone cypionate, Luteinizing hormone-releasing hormone (LHRH) analogue, Enzalutamide Salvage HDR for Locally Recurrent Prostate Cancer NCT04231006NA1 site📍 Aarhus Aarhus University Hospital · Tests: High dose rate brachytherapy Focal Micro-boost Strategy in Patients With Intermediate- to High-risk Prostate Cancer (IR-HR PCa) Undergoing Hypofractionated Radiotherapy NCT07792993n/a1 site📍 Rome Regina Elena Cancer Institute Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery. NCT07483658NA4 sites📍 Gatineau📍 Montreal📍 Montreal CHU de Quebec-Universite Laval · Tests: Standard Fractionation Post-Operative Salvage Radiotherapy (25 fractions), Hypofractionated Post-Operative Salvage Radi… 177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer NCT06449781Phase 21 site📍 Gliwice Maria Sklodowska-Curie National Research Institute of Oncol… · Tests: Lutetium (177Lu) vipivotide tetraxetan Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer NCT06631521Phase 11 site📍 Orlando AdventHealth · Tests: Darolutamide, Relugolix, Radical Prostatectomy Evaluation of PSMA-PET and mpMRI in High-risk Prostate Cancer - Using Histopathologic Validation NCT06565247Phase 32 sites📍 Malmö📍 Umeå Region Västerbotten · Tests: [18F]PSMA-PET, MRI sequences optimized for prostate cancer examinations A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation NCT06952803Phase 3346 sites📍 Phoenix📍 Tucson📍 La Jolla AstraZeneca · Tests: Saruparib, Placebo, Abiraterone + Prednisolone/Prednisone, Androgen Deprivation Therapy (ADT) Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer NCT06613100Phase 19 sites📍 San Francisco📍 St Louis📍 Columbus Amgen · Tests: Xaluritamig, GnRH Antagonist Tb-PSMA-I&T Radionuclide Before Radical Prostatectomy in Patients With Locally Advanced Prostate Cancer - TbeforePROST Trial. NCT07208240Phase 1, Phase 21 site📍 Petah Tikva Rabin Medical Center · Tests: Tb-PSMA-I&T (Tb-PSMA) High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma NCT04945642NA1 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: High-Dose Rate Brachytherapy, Stereotactic Body Radiation Therapy Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial NCT06067269Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Apalutamide, Biospecimen Collection, Computed Tomography, Gallium Ga 68 Gozetotide, Guided Stereotactic Body Radiation … Detection of Minimal Residual Disease Post-prostatectomy NCT07334275n/a1 site📍 Nijmegen Radboud University Medical Center
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