🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Hypopharyngeal Squamous Cell Carcinoma

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites📍 Santa Rosa📍 Hartford📍 Washington D.C. VM Oncology, LLC · Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Res… Neoadjuvant EGFR-ADC Combined With Anti-PD-1 Monoclonal Antibody in Resectable Locally Advanced Hypopharyngeal Squamous Cell Carcinoma NCT07665190Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Becotatug Vedotin and Pucotenlimab FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC NCT06788990Phase 2, Phase 3231 sites📍 Birmingham📍 Phoenix📍 La Jolla Bicara Therapeutics · Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDA®), Placebo The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma NCT05494190NA3 sites📍 Harbin📍 Jinan📍 Shanghai Eye & ENT Hospital of Fudan University · Tests: Docetaxel, Cisplatin, Capecitabine, Concomitant chemoradiotherapy, Surgery Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Advanced Head and Neck Cancer Who Cannot Receive Cisplatin NCT07441681Phase 3150 sites📍 Birmingham📍 Anaheim📍 Baldwin Park NRG Oncology · Tests: Biospecimen Collection, Carboplatin, Cetuximab, Computed Tomography, Intensity-Modulated Radiation Therapy Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites📍 Essen📍 Hanover AIO-Studien-gGmbH · Tests: data collection Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery NCT02734537Phase 2679 sites📍 Birmingham📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: Cisplatin, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site📍 Atlanta Emory University · Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer NCT06914999EARLY Phase 11 site📍 Atlanta Emory University · Tests: Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy, Intensity-Modulated Radiation Therapy, P… Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer NCT05544136Phase 26 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: 18F-FMISO PET/CT scan, Chemoradiation therapy, Carboplatin Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites📍 Irvine📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograp… Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer NCT07058805Phase 23 sites📍 Basel📍 Bern📍 Zurich Olgun Elicin · Tests: Compartmentalized Postoperative Radiotherapy Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment NCT06589804Phase 3202 sites📍 Little Rock📍 Marysville📍 Palo Alto National Cancer Institute (NCI) · Tests: Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites📍 Nashville📍 Nashville📍 Nashville Vanderbilt University Medical Center · Tests: biologic sample preservation procedure, medical chart review Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites📍 Hanover📍 Barcelona Fundació Institut de Recerca de l'Hospital de la Santa Creu… · Tests: Afatinib SBRT Followed by Chemoimmunotherapy of Toripalimab Plus Docetaxel and Cisplatin for Larynx Preservation in Patients with Locally Regionally Advanced Squamous Cell Carcinoma of the Larynx and Hypopharynx NCT06611137Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: SBRT+Toripalimab Plus Docetaxel and Cisplatin Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy 5-Fluorouracil Response and Optimization STudy (The FROST Trial) NCT07419464Phase 21 site📍 St Louis Washington University School of Medicine · Tests: 5-Fluorouracil European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites📍 Mannheim📍 Ulm📍 München University of Leipzig · Tests: KEYTRUDA® A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) NCT07063212Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Sacituzumab Govitecan, Cetuximab De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck NCT06030440Phase 2, Phase 31 site📍 Erlangen University of Erlangen-Nürnberg Medical School · Tests: Eliminating RT to the elective neck, RT standard of care Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy NCT05337631n/a18 sites📍 Baltimore📍 New York📍 Cleveland University Hospital Freiburg Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck NCT01473784NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: transoral robotic surgery, quality of life assessment Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial NCT06636734Phase 22 sites📍 Atlanta📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Lovastatin, Magnetic Resonance Imaging, Pembrolizumab Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design NCT02128906Phase 21 site📍 Pittsburgh Christopher Wilke · Tests: Cisplatin, IMRT, Docetaxel, Cetuximab
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy