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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Intrathecal Drug Delivery

Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty NCT06837844NA1 site📍 Kafr ash Shaykh Kafrelsheikh University · Tests: Intrathecal Dexmedetomidine, Adductor Canal Block, Intrathecal Dexmedetomidine + Adductor Canal Block Outcomes of Neurosurgical Tone Management NCT07817745n/a1 site📍 Boston Boston Children's Hospital Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls. NCT06692712Phase 32 sites📍 Dallas📍 Barcelona Elpida Therapeutics SPC · Tests: MELPIDA Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases NCT07304739Phase 23 sites📍 Cangzhou📍 Tianjin📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Furmonertinib, Intrathecal chemotherapy, Stereotactic radiotherapy Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia NCT07386353Phase 41 site📍 Funchal Hospital Central do Funchal · Tests: Intrathecal Morphine, Epidural Morphine Intrathecal Therapy Versus Standard Care for Severe Cancer Pain NCT07691840NA1 site📍 Jette Universitair Ziekenhuis Brussel · Tests: Intrathecal Drug Delivery, Comprehensive Medical Management Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC NCT05805631Phase 21 site📍 Taipei Taipei Veterans General Hospital, Taiwan · Tests: Pemetrexed Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC NCT06663306Phase 11 site📍 Shanghai Shanghai Chest Hospital · Tests: Pemetrexed, Bevacizumab Treatment of Vasospasm of Aneurysmal Subarachnoid Hemorrhage With Intrathecal Nicardipine - FAST-IT Trial NCT06329635NA28 sites📍 Hefei📍 Beijing📍 Chongqing The Affiliated Hospital Of Guizhou Medical University · Tests: Intrathecal Nicardipine, No intervention Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL NCT02836158Phase 2, Phase 31 site📍 Beijing Navy General Hospital, Beijing · Tests: R-IDARAM plus intrathecal chemotherapy Safety of Cultured Allogeneic Adult Umbilical-cord or Placental Derived Mesenchymal Stem Cell Intrathecal Injection for SCI NCT05018793Phase 12 sites📍 Naples📍 Athens The Foundation for Orthopaedics and Regenerative Medicine · Tests: Cultured Allogeneic Adult Umbilical-cord or Placental Derived Mesenchymal Stem Cell Intrathecal injection Double-Dose Third-Generation EGFR-TKI Plus Bevacizumab and Intrathecal Chemotherapy for Refractory Leptomeningeal Metastatic NSCLC: A Phase II Study NCT07398599NA1 site📍 Nanchang Second Affiliated Hospital of Nanchang University · Tests: a combined regimen consisting of double-dose third-generation EGFR-TKI, bevacizumab, and intrathecal chemotherapy in pa… Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26) NCT05112549Phase 19 sites📍 Bonn📍 Freiburg im Breisgau📍 Heidelberg University Hospital Tuebingen · Tests: Nivolumab [Opdivo] Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T) NCT07215416Phase 1, Phase 21 site📍 Boston Timothy Yu · Tests: Antisense oligonucleotide targeting the ATM gene Patient Preference and Long-term Outcomes in Persistent Spinal Pain Syndrome: A Prospective Study Comparing Spinal Cord Stimulation to Intrathecal Drug Delivery. NCT07091123Phase 41 site📍 Cleveland University Hospitals Cleveland Medical Center · Tests: Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS) Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) NCT05518188Phase 1, Phase 21 site📍 Dallas Elpida Therapeutics SPC · Tests: MELPIDA Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery NCT06935708Phase 41 site📍 Split Meri Mirceta · Tests: Intrathecal Morphine, Epidural Analgesia A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease NCT06585449Phase 119 sites📍 Edmonton📍 Montreal📍 Ottawa Alnylam Pharmaceuticals · Tests: ALN-HTT02, Placebo Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation NCT06942039EARLY Phase 112 sites📍 Calgary📍 Vancouver📍 Winnipeg C17 Council · Tests: Cytarabine IT, hydrocortisone, Cisplatin, Vincristine, Etoposide Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer NCT06431685Phase 11 site📍 Chengdu Sichuan University · Tests: Whole Brain Low Dose Radiotherapy, Pemetrexed, Sintilimab, Chemotherapy Intrathecal Morphine Versus Intravenous Methadone for Postoperative Analgesia Following Retroperitoneal Lymph Node Dissection. NCT06593665Phase 32 sites📍 Indianapolis📍 Indianapolis Indiana University · Tests: Inrathecal Morphine, Intravenous Methadone R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse NCT05257018Phase 22 sites📍 Shanghai📍 Ürümqi Fudan University · Tests: R-CDOP+intrathecal MTX The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment NCT07203742NA1 site📍 Izmir Ege University · Tests: mandala painting Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy NCT05866419NA21 sites📍 Phoenix📍 Orange📍 Palo Alto Alcyone Therapeutics, Inc · Tests: ThecaFlex DRx System Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III NCT06971094Phase 37 sites📍 Beijing📍 Beijing📍 Beijing GeneCradle Inc · Tests: GC101 adeno-associated virus injection Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery NCT06525740Phase 41 site📍 Rochester Mayo Clinic · Tests: Hydromorphone, Methadone, Questionnaire Administration Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib. NCT06296745Phase 21 site📍 Huizhou Guangzhou Medical University · Tests: Pemetrexed Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN) NCT06980948Phase 1, Phase 211 sites📍 Scottsdale📍 Little Rock📍 La Jolla Sangamo Therapeutics · Tests: ST-503, Sham (No Treatment) Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases NCT07092202Phase 41 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: Firmonertinib, Intrathecal injection of pemetrexed A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS) NCT07290062Phase 17 sites📍 La Jolla📍 Palo Alto📍 Baltimore Insmed Gene Therapy LLC · Tests: INS1202
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