🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Langerhans Cell Histiocytosis

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET NCT05093335EARLY Phase 11 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: [68Ga]-Pentixafor Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD) NCT06192576n/a6 sites📍 Chicago📍 Cincinnati📍 Columbus Sanofi · Tests: Olipudase alfa Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children NCT07022834Phase 21 site📍 Chengdu West China Second University Hospital · Tests: Dabrafenib or Trametinib and Clofarabine Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions NCT07371182NA11 sites📍 Hefei📍 Nanning📍 Guiyang West China Second University Hospital · Tests: Luvometinib Biomarkers for Diagnostic, Prognostic and of Response to Treatment in Adult Langerhans Cell Histiocytosis NCT06197204n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Blood sampling, Biopsy, Blood sampling A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis NCT07054515Phase 339 sites📍 Oakland📍 Minneapolis📍 Rochester Azafaros B.V. · Tests: AZ-3102, Placebo Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT NCT01962415Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: Hydroxyurea, Alemtuzumab, Fludarabine, Melphalan, Thiotepa Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study NCT04665674n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Standard of care Establishing a National Egyptian HLH Registry (NEHR) NCT07800234n/a2 sites📍 Cairo📍 Cairo Ain Shams University CytOSorb TreatMent Of Critically Ill PatientS Registry NCT05146336n/a28 sites📍 Klagenfurt📍 Vienna📍 Aachen CytoSorbents, Inc · Tests: CytoSorb Supportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic Diseases NCT03990428n/a1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: online surveys DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. NCT07440290Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Dabrafenib, Trametinib Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) NCT06160791Phase 24 sites📍 Irvine📍 Sacramento📍 San Diego Jerry Lee, MD, MSc, MPhil · Tests: Ruxolitinib, Etoposide, Dexamethasone, Non-interventional Imaging, Research Biopsy A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC) NCT07082725Phase 334 sites📍 Oakland📍 Minneapolis📍 Rochester Azafaros B.V. · Tests: Nizubaglustat, Placebo Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib NCT06582745Phase 21 site📍 Fort Worth Cook Children's Health Care System · Tests: Trametinib Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses NCT03329274n/a1 site📍 New York Memorial Sloan Kettering Cancer Center A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis NCT05828069Phase 2123 sites📍 Birmingham📍 Little Rock📍 Downey National Cancer Institute (NCI) · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test Prospective Cohort for Adult Hemophagocytosis NCT03117010n/a1 site📍 Seoul Samsung Medical Center · Tests: Steroids, Etoposide Mirdametinib in Histiocytic Disorders NCT06153173Phase 21 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati · Tests: Mirdametinib Study of the Prevalence of Acid Sphingomyelinase Deficiency/Niemann Pick AB and B Disease in Patients With Diffuse Interstitial Lung Disease NCT06869499NA1 site📍 Paris Wladimir MAUHIN, Dr · Tests: Blood sampling for dosage Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site📍 Pittsburgh Paul Szabolcs · Tests: data collection Surveillance and Tracking the Outcomes of Chronic Latent EBV Infection NCT03491605n/a1 site📍 Wuhan Huazhong University of Science and Technology · Tests: peripheral EBV-DNA load GammaGA: Prevalence of Acid Sphingomyelinase Deficiency Disease (ASMD) and Gaucher Disease in Patients With Monoclonal Gammopathies and/or Multiple Myeloma NCT05992532n/a23 sites📍 Vitoria-Gasteiz📍 Almería📍 Palma de Mallorca Fundación Española de Hematología y Hemoterapía ECD-Score: a Study on Erdheim-Chester Disease NCT07454343n/a7 sites📍 Bethesda📍 Rochester📍 New York Meyer Children's Hospital IRCCS Hemophagocytic Lymphohistiocytosis After Allogeneic Stem Cell Transplantation NCT07905066n/a1 site📍 Beijing Peking University People's Hospital Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites📍 Scottsdale📍 Rochester Mayo Clinic · Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Assessing the Presence of CT-DNA in Lymphoma Associated HLH NCT05702502n/a1 site📍 Nottingham Nottingham University Hospitals NHS Trust Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma NCT07270835Phase 41 site📍 Suzhou The First Affiliated Hospital of Soochow University · Tests: Rituximab, Zanubrutinib Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH) NCT02670707Phase 311 sites📍 Palo Alto📍 San Diego📍 Minneapolis Baylor College of Medicine · Tests: Cytarabine, Vinblastine/prednisone
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy